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• W2105256594 abstract "An outbreak of infections due to multiple antibiotic-resistant bacteria took place over a period of approximately 18 months in a renal unit. Strains of Escherichia coli, Enterobacter aerogenes, Klebsiella pneumoniae, Citrobacter spp. and Pseudomonas spp. were involved, and a variety of antibiotic resistances was encountered. Closely related plasmids encoding resistance to aztreonam, ceftazidime and piperacillin, possibly derived from an archetypal plasmid of 105 kb were found in the majority of isolates examined. After limiting the use of aztreonam the incidence of new patient isolates of multiple-resistant organisms was greatly reduced. This study demonstrated how molecular studies can contribute to the control of an outbreak situation in a hospital unit by providing an impetus to reduce the use of specific antibiotics." @default.
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• W2105256594 date "1995-08-01" @default.
• W2105256594 modified "2023-09-26" @default.
• W2105256594 title "Control of infection with multiple antibiotic resistant bacteria in a hospital renal unit: the value of plasmid characterization" @default.
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• W2105256594 doi "https://doi.org/10.1017/s095026880005812x" @default.
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