FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2105279305> ?p ?o ?g. }

• W2105279305 abstract "Superoxide anion plays important roles in vascular disease states. Increased superoxide production contributes to reduced nitric oxide (NO) bioactivity and endothelial dysfunction in experimental models of vascular disease. We measured superoxide production by NAD(P)H oxidase in human blood vessels and examined the relationships between NAD(P)H oxidase activity, NO-mediated endothelial function, and clinical risk factors for atherosclerosis. Endothelium-dependent vasorelaxations and direct measurements of vascular superoxide production were determined in human saphenous veins obtained from 133 patients with coronary artery disease and identified risk factors. The predominant source of vascular superoxide production was an NAD(P)H-dependent oxidase. Increased vascular NAD(P)H oxidase activity was associated with reduced NO-mediated vasorelaxation. Furthermore, reduced endothelial vasorelaxations and increased vascular NAD(P)H oxidase activity were both associated with increased clinical risk factors for atherosclerosis. Diabetes and hypercholesterolemia were independently associated with increased NADH-dependent superoxide production. The association of increased vascular NAD(P)H oxidase activity with endothelial dysfunction and with clinical risk factors suggests an important role for NAD(P)H oxidase-mediated superoxide production in human atherosclerosis. The full text of this article is available at http://www.circresaha.org." @default.
• W2105279305 created "2016-06-24" @default.
• W2105279305 creator A5000195279 @default.
• W2105279305 creator A5021351903 @default.
• W2105279305 creator A5022528873 @default.
• W2105279305 creator A5036938446 @default.
• W2105279305 creator A5038463084 @default.
• W2105279305 creator A5070934854 @default.
• W2105279305 creator A5078481114 @default.
• W2105279305 date "2000-05-12" @default.
• W2105279305 modified "2023-10-10" @default.
• W2105279305 title "Vascular Superoxide Production by NAD(P)H Oxidase" @default.
• W2105279305 cites W143010615 @default.
• W2105279305 cites W1767469279 @default.
• W2105279305 cites W1976555160 @default.
• W2105279305 cites W1997367079 @default.
• W2105279305 cites W2012018808 @default.
• W2105279305 cites W2014083905 @default.
• W2105279305 cites W2022264732 @default.
• W2105279305 cites W2026425756 @default.
• W2105279305 cites W2041394247 @default.
• W2105279305 cites W2050420714 @default.
• W2105279305 cites W2060466526 @default.
• W2105279305 cites W2067372623 @default.
• W2105279305 cites W2093518775 @default.
• W2105279305 cites W2101745219 @default.
• W2105279305 cites W2110676635 @default.
• W2105279305 cites W2135633069 @default.
• W2105279305 cites W2139491374 @default.
• W2105279305 cites W2144188723 @default.
• W2105279305 cites W2156490538 @default.
• W2105279305 cites W2161420495 @default.
• W2105279305 cites W2166662752 @default.
• W2105279305 doi "https://doi.org/10.1161/01.res.86.9.e85" @default.
• W2105279305 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10807876" @default.
• W2105279305 hasPublicationYear "2000" @default.
• W2105279305 type Work @default.
• W2105279305 sameAs 2105279305 @default.
• W2105279305 citedByCount "420" @default.
• W2105279305 countsByYear W21052793052012 @default.
• W2105279305 countsByYear W21052793052013 @default.
• W2105279305 countsByYear W21052793052014 @default.
• W2105279305 countsByYear W21052793052015 @default.
• W2105279305 countsByYear W21052793052016 @default.
• W2105279305 countsByYear W21052793052017 @default.
• W2105279305 countsByYear W21052793052018 @default.
• W2105279305 countsByYear W21052793052019 @default.
• W2105279305 countsByYear W21052793052020 @default.
• W2105279305 countsByYear W21052793052021 @default.
• W2105279305 countsByYear W21052793052022 @default.
• W2105279305 countsByYear W21052793052023 @default.
• W2105279305 crossrefType "journal-article" @default.
• W2105279305 hasAuthorship W2105279305A5000195279 @default.
• W2105279305 hasAuthorship W2105279305A5021351903 @default.
• W2105279305 hasAuthorship W2105279305A5022528873 @default.
• W2105279305 hasAuthorship W2105279305A5036938446 @default.
• W2105279305 hasAuthorship W2105279305A5038463084 @default.
• W2105279305 hasAuthorship W2105279305A5070934854 @default.
• W2105279305 hasAuthorship W2105279305A5078481114 @default.
• W2105279305 hasBestOaLocation W21052793051 @default.
• W2105279305 hasConcept C126322002 @default.
• W2105279305 hasConcept C134018914 @default.
• W2105279305 hasConcept C181199279 @default.
• W2105279305 hasConcept C185592680 @default.
• W2105279305 hasConcept C2776992346 @default.
• W2105279305 hasConcept C2780795997 @default.
• W2105279305 hasConcept C2781252958 @default.
• W2105279305 hasConcept C38485361 @default.
• W2105279305 hasConcept C519581460 @default.
• W2105279305 hasConcept C55493867 @default.
• W2105279305 hasConcept C71924100 @default.
• W2105279305 hasConcept C75520062 @default.
• W2105279305 hasConcept C86803240 @default.
• W2105279305 hasConceptScore W2105279305C126322002 @default.
• W2105279305 hasConceptScore W2105279305C134018914 @default.
• W2105279305 hasConceptScore W2105279305C181199279 @default.
• W2105279305 hasConceptScore W2105279305C185592680 @default.
• W2105279305 hasConceptScore W2105279305C2776992346 @default.
• W2105279305 hasConceptScore W2105279305C2780795997 @default.
• W2105279305 hasConceptScore W2105279305C2781252958 @default.
• W2105279305 hasConceptScore W2105279305C38485361 @default.
• W2105279305 hasConceptScore W2105279305C519581460 @default.
• W2105279305 hasConceptScore W2105279305C55493867 @default.
• W2105279305 hasConceptScore W2105279305C71924100 @default.
• W2105279305 hasConceptScore W2105279305C75520062 @default.
• W2105279305 hasConceptScore W2105279305C86803240 @default.
• W2105279305 hasIssue "9" @default.
• W2105279305 hasLocation W21052793051 @default.
• W2105279305 hasLocation W21052793052 @default.
• W2105279305 hasOpenAccess W2105279305 @default.
• W2105279305 hasPrimaryLocation W21052793051 @default.
• W2105279305 hasRelatedWork W1964628067 @default.
• W2105279305 hasRelatedWork W1971463556 @default.
• W2105279305 hasRelatedWork W2000155150 @default.
• W2105279305 hasRelatedWork W2006945041 @default.
• W2105279305 hasRelatedWork W2033062120 @default.
• W2105279305 hasRelatedWork W2046543299 @default.
• W2105279305 hasRelatedWork W2085137779 @default.
• W2105279305 hasRelatedWork W2095119186 @default.
• W2105279305 hasRelatedWork W2105279305 @default.

• next