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• W2105294966 abstract "Aim: To investigate serum levels of B-cell activating factor (BAFF) in the patients with polymyositis (PM) and dermatomyositis (DM), and to systematically examine the association between serum BAFF levels and disease activity in PM/DM patients. Patients & methods: A cross-sectional analysis included 92 PM/DM patients and 25 healthy control subjects. A longitudinal study followed 24 patients. Serum BAFF concentrations were detected by the ELISA method. Results: Serum BAFF levels in PM/DM patients were significantly higher than those in healthy controls. A cross-sectional assessment revealed a modest correlation between serum BAFF levels and global disease activity and a mild correlation between serum BAFF levels and muscle disease activity. The longitudinal study showed that serum BAFF levels modestly correlated with global disease activity and muscle disease activity. Conclusion: Resulting data showed high serum BAFF levels in PM/DM patients and suggested BAFF as a serological biomarker for PM/DM disease activity." @default.
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• W2105294966 date "2014-03-01" @default.
• W2105294966 modified "2023-09-30" @default.
• W2105294966 title "B-cell activating factor as a serological biomarker for polymyositis and dermatomyositis" @default.
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• W2105294966 doi "https://doi.org/10.2217/bmm.13.124" @default.
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