FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2105322402> ?p ?o ?g. }

• W2105322402 endingPage "P27" @default.
• W2105322402 startingPage "P27" @default.
• W2105322402 abstract "Although Health Canada approved generic warfarins in Year 2000, there is still controversy over the interchangeability of these products with brand-name Coumadin. Since a large population of patients require warfarin and it has a narrow margin of efficacy and safety, it is vital to ensure that generic brands can be safely interchanged with Coumadin. Multiple N-of-1 randomized double blind crossover trials switched outpatients between generic warfarin and Coumadin over a period of thirty weeks. Study patients were on each drug for 5 × 3-week periods with International Normalized Ratio (INR) measurements twice per period. Outcomes included mean INR results and proportion of dosage adjustments that were required with each brand. Inter-patient and intra-patient differences between generic warfarin and Coumadin were compared. Study patient results were also compared with those of a retrospective control group, maintained on Coumadin only. The 6 patients (96% power to detect a difference of greater than 0.5 INR units between warfarin brands) showed no significant difference between warfarin brands in terms of mean INR results (p = 0.485) and proportion of dosage adjustments required with each brand (p = 0.264). Study patients experienced less inter- and intra-subject INR variation than the historical control group, though the difference was not statistically significant. Patients can safely and effectively switch between generic warfarin and Coumadin. Clinical Pharmacology & Therapeutics (2004) 75, P27–P27; doi: 10.1016/j.clpt.2003.11.103" @default.
• W2105322402 created "2016-06-24" @default.
• W2105322402 creator A5006802149 @default.
• W2105322402 creator A5015707477 @default.
• W2105322402 creator A5018878339 @default.
• W2105322402 creator A5028992865 @default.
• W2105322402 creator A5029801001 @default.
• W2105322402 creator A5037848403 @default.
• W2105322402 creator A5045765865 @default.
• W2105322402 creator A5069466103 @default.
• W2105322402 creator A5079941141 @default.
• W2105322402 date "2004-02-01" @default.
• W2105322402 modified "2023-09-26" @default.
• W2105322402 title "Are brand-name and generic warfarin interchangeable?" @default.
• W2105322402 cites W1484864026 @default.
• W2105322402 cites W1569288582 @default.
• W2105322402 cites W166273424 @default.
• W2105322402 cites W173430487 @default.
• W2105322402 cites W1992841330 @default.
• W2105322402 cites W2019436402 @default.
• W2105322402 cites W2030262988 @default.
• W2105322402 cites W2031149324 @default.
• W2105322402 cites W2057484890 @default.
• W2105322402 cites W2075206329 @default.
• W2105322402 cites W2106318464 @default.
• W2105322402 cites W2125650394 @default.
• W2105322402 cites W2133206482 @default.
• W2105322402 cites W2157932545 @default.
• W2105322402 cites W2160787317 @default.
• W2105322402 cites W2170931442 @default.
• W2105322402 cites W2440222688 @default.
• W2105322402 doi "https://doi.org/10.1016/j.clpt.2003.11.103" @default.
• W2105322402 hasPublicationYear "2004" @default.
• W2105322402 type Work @default.
• W2105322402 sameAs 2105322402 @default.
• W2105322402 citedByCount "7" @default.
• W2105322402 countsByYear W21053224022018 @default.
• W2105322402 countsByYear W21053224022021 @default.
• W2105322402 crossrefType "journal-article" @default.
• W2105322402 hasAuthorship W2105322402A5006802149 @default.
• W2105322402 hasAuthorship W2105322402A5015707477 @default.
• W2105322402 hasAuthorship W2105322402A5018878339 @default.
• W2105322402 hasAuthorship W2105322402A5028992865 @default.
• W2105322402 hasAuthorship W2105322402A5029801001 @default.
• W2105322402 hasAuthorship W2105322402A5037848403 @default.
• W2105322402 hasAuthorship W2105322402A5045765865 @default.
• W2105322402 hasAuthorship W2105322402A5069466103 @default.
• W2105322402 hasAuthorship W2105322402A5079941141 @default.
• W2105322402 hasConcept C112698675 @default.
• W2105322402 hasConcept C126322002 @default.
• W2105322402 hasConcept C142724271 @default.
• W2105322402 hasConcept C144133560 @default.
• W2105322402 hasConcept C199360897 @default.
• W2105322402 hasConcept C204787440 @default.
• W2105322402 hasConcept C27081682 @default.
• W2105322402 hasConcept C2776301958 @default.
• W2105322402 hasConcept C2776396487 @default.
• W2105322402 hasConcept C2779161974 @default.
• W2105322402 hasConcept C2779606619 @default.
• W2105322402 hasConcept C2780035454 @default.
• W2105322402 hasConcept C2908647359 @default.
• W2105322402 hasConcept C2992181568 @default.
• W2105322402 hasConcept C41008148 @default.
• W2105322402 hasConcept C42219234 @default.
• W2105322402 hasConcept C63433958 @default.
• W2105322402 hasConcept C71924100 @default.
• W2105322402 hasConcept C87813604 @default.
• W2105322402 hasConcept C98274493 @default.
• W2105322402 hasConcept C99454951 @default.
• W2105322402 hasConceptScore W2105322402C112698675 @default.
• W2105322402 hasConceptScore W2105322402C126322002 @default.
• W2105322402 hasConceptScore W2105322402C142724271 @default.
• W2105322402 hasConceptScore W2105322402C144133560 @default.
• W2105322402 hasConceptScore W2105322402C199360897 @default.
• W2105322402 hasConceptScore W2105322402C204787440 @default.
• W2105322402 hasConceptScore W2105322402C27081682 @default.
• W2105322402 hasConceptScore W2105322402C2776301958 @default.
• W2105322402 hasConceptScore W2105322402C2776396487 @default.
• W2105322402 hasConceptScore W2105322402C2779161974 @default.
• W2105322402 hasConceptScore W2105322402C2779606619 @default.
• W2105322402 hasConceptScore W2105322402C2780035454 @default.
• W2105322402 hasConceptScore W2105322402C2908647359 @default.
• W2105322402 hasConceptScore W2105322402C2992181568 @default.
• W2105322402 hasConceptScore W2105322402C41008148 @default.
• W2105322402 hasConceptScore W2105322402C42219234 @default.
• W2105322402 hasConceptScore W2105322402C63433958 @default.
• W2105322402 hasConceptScore W2105322402C71924100 @default.
• W2105322402 hasConceptScore W2105322402C87813604 @default.
• W2105322402 hasConceptScore W2105322402C98274493 @default.
• W2105322402 hasConceptScore W2105322402C99454951 @default.
• W2105322402 hasIssue "2" @default.
• W2105322402 hasLocation W21053224021 @default.
• W2105322402 hasOpenAccess W2105322402 @default.
• W2105322402 hasPrimaryLocation W21053224021 @default.
• W2105322402 hasRelatedWork W1663023987 @default.
• W2105322402 hasRelatedWork W1995771806 @default.
• W2105322402 hasRelatedWork W2095722916 @default.
• W2105322402 hasRelatedWork W2105322402 @default.

• next