Matches in SemOpenAlex for { <https://semopenalex.org/work/W2105343513> ?p ?o ?g. }
- W2105343513 endingPage "5582" @default.
- W2105343513 startingPage "5572" @default.
- W2105343513 abstract "Despite the antioxidant potential of vitamin A, recent studies reported that chronic retinol ester supplementation can also exert pro-oxidant effects and neurotoxicity in vivo and raises the mortality rates among healthy subjects. Our aim was to find evidence for a safer (i.e., less toxic) molecule with provitamin A activity. Therefore, we investigated whether chronic supplementation of healthy Wistar rats with β-carotene (0.6, 3, and 6 mg/kg/day) would demonstrate antioxidant characteristics without leading to pro-oxidant side effects in the brain. Total reactive antioxidant potential (TRAP), thiobarbituric reactive species level (TBARS), and total reduced thiol content (SH) were evaluated in plasma. TBARS and SH were additionally evaluated in selected brain regions together with superoxide dismutase (SOD) and catalase (CAT) activity. In the present study, we show that β-carotene is able to exert antioxidant activity in plasma without triggering pro-oxidant events in the brain, providing evidence that may justify its further evaluation as a safer nutritional supplement with provitamin A activity." @default.
- W2105343513 created "2016-06-24" @default.
- W2105343513 creator A5003201985 @default.
- W2105343513 creator A5052970692 @default.
- W2105343513 creator A5056281232 @default.
- W2105343513 creator A5065172877 @default.
- W2105343513 creator A5075209354 @default.
- W2105343513 creator A5088853716 @default.
- W2105343513 date "2014-12-01" @default.
- W2105343513 modified "2023-10-12" @default.
- W2105343513 title "Supplementation of Adult Rats with Moderate Amounts of β-Carotene Modulates the Redox Status in Plasma without Exerting Pro-Oxidant Effects in the Brain: A Safer Alternative to Food Fortification with Vitamin A?" @default.
- W2105343513 cites W1525444530 @default.
- W2105343513 cites W1526677845 @default.
- W2105343513 cites W1538399032 @default.
- W2105343513 cites W1567351354 @default.
- W2105343513 cites W1598777337 @default.
- W2105343513 cites W1750690213 @default.
- W2105343513 cites W1775749144 @default.
- W2105343513 cites W1825554421 @default.
- W2105343513 cites W1914316152 @default.
- W2105343513 cites W191793640 @default.
- W2105343513 cites W1929245453 @default.
- W2105343513 cites W1965336187 @default.
- W2105343513 cites W1969802341 @default.
- W2105343513 cites W1974380679 @default.
- W2105343513 cites W1993383247 @default.
- W2105343513 cites W1998047704 @default.
- W2105343513 cites W1999863641 @default.
- W2105343513 cites W2006370393 @default.
- W2105343513 cites W2007649442 @default.
- W2105343513 cites W2018829895 @default.
- W2105343513 cites W2038213763 @default.
- W2105343513 cites W2038460919 @default.
- W2105343513 cites W2052257773 @default.
- W2105343513 cites W2059167445 @default.
- W2105343513 cites W2081000970 @default.
- W2105343513 cites W2086169535 @default.
- W2105343513 cites W2094399331 @default.
- W2105343513 cites W2111292506 @default.
- W2105343513 cites W2112679668 @default.
- W2105343513 cites W2115327946 @default.
- W2105343513 cites W2116424646 @default.
- W2105343513 cites W2117825326 @default.
- W2105343513 cites W2129491949 @default.
- W2105343513 cites W2138744792 @default.
- W2105343513 cites W2144548956 @default.
- W2105343513 cites W2149697700 @default.
- W2105343513 cites W2150108820 @default.
- W2105343513 cites W2154441568 @default.
- W2105343513 cites W2163641344 @default.
- W2105343513 cites W2165201727 @default.
- W2105343513 cites W2171469783 @default.
- W2105343513 cites W2174121794 @default.
- W2105343513 cites W2315403385 @default.
- W2105343513 cites W2317242858 @default.
- W2105343513 cites W4210988566 @default.
- W2105343513 cites W4238506171 @default.
- W2105343513 doi "https://doi.org/10.3390/nu6125572" @default.
- W2105343513 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4276984" @default.
- W2105343513 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25470379" @default.
- W2105343513 hasPublicationYear "2014" @default.
- W2105343513 type Work @default.
- W2105343513 sameAs 2105343513 @default.
- W2105343513 citedByCount "11" @default.
- W2105343513 countsByYear W21053435132015 @default.
- W2105343513 countsByYear W21053435132016 @default.
- W2105343513 countsByYear W21053435132018 @default.
- W2105343513 countsByYear W21053435132020 @default.
- W2105343513 countsByYear W21053435132023 @default.
- W2105343513 crossrefType "journal-article" @default.
- W2105343513 hasAuthorship W2105343513A5003201985 @default.
- W2105343513 hasAuthorship W2105343513A5052970692 @default.
- W2105343513 hasAuthorship W2105343513A5056281232 @default.
- W2105343513 hasAuthorship W2105343513A5065172877 @default.
- W2105343513 hasAuthorship W2105343513A5075209354 @default.
- W2105343513 hasAuthorship W2105343513A5088853716 @default.
- W2105343513 hasBestOaLocation W21053435131 @default.
- W2105343513 hasConcept C126322002 @default.
- W2105343513 hasConcept C134018914 @default.
- W2105343513 hasConcept C185592680 @default.
- W2105343513 hasConcept C2775838275 @default.
- W2105343513 hasConcept C2776151105 @default.
- W2105343513 hasConcept C2776573510 @default.
- W2105343513 hasConcept C2776940978 @default.
- W2105343513 hasConcept C2777352226 @default.
- W2105343513 hasConcept C2777551382 @default.
- W2105343513 hasConcept C2778004101 @default.
- W2105343513 hasConcept C2778979269 @default.
- W2105343513 hasConcept C2779491297 @default.
- W2105343513 hasConcept C2779573558 @default.
- W2105343513 hasConcept C2780829032 @default.
- W2105343513 hasConcept C28781525 @default.
- W2105343513 hasConcept C29730261 @default.
- W2105343513 hasConcept C31903555 @default.
- W2105343513 hasConcept C55493867 @default.
- W2105343513 hasConcept C71924100 @default.
- W2105343513 hasConcept C98274493 @default.
- W2105343513 hasConceptScore W2105343513C126322002 @default.