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- W2105364144 endingPage "1056" @default.
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- W2105364144 abstract "Alloantibodies to HLA class I or II and other antigens expressed by endothelium cause a variety of effects on renal transplants, ranging from acute to chronic rejection, and even apparent graft acceptance (accommodation). Recognition of these conditions and appropriate therapy requires demonstration of C4d in biopsies, commonly confirmed by tests for circulating alloantibody. Substantial practical experience by pathologists in the interpretation and pitfalls of C4d stains are reviewed along with considerations of the clinical significance and pathologic mechanisms of the different effects of antibody on the endothelium of the renal allograft. Clinical trials will be needed to ascertain the optimal treatment for the newly appreciated conditions chronic humoral rejection and accommodation." @default.
- W2105364144 created "2016-06-24" @default.
- W2105364144 creator A5019248592 @default.
- W2105364144 date "2007-04-01" @default.
- W2105364144 modified "2023-10-15" @default.
- W2105364144 title "Antibody-Mediated Renal Allograft Rejection" @default.
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- W2105364144 doi "https://doi.org/10.1681/asn.2007010073" @default.
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