Matches in SemOpenAlex for { <https://semopenalex.org/work/W2105393912> ?p ?o ?g. }
- W2105393912 abstract "Bisphosphonates (BPs) are approved as standard therapy in breast cancer for the treatment of bone metastases, since they were demonstrated to reduce the prevalence of skeletal-related events including fractures and hypercalcemia. In the adjuvant setting, BPs can be given to prevent and treat tumor therapy-induced bone loss in premenopausal and postmenopausal women and, owing to their beneficial effect on bone turnover, have also been evaluated for prevention of bone metastases occurrence. In this article we will review the mechanisms through which BPs have been demonstrated to prevent premetastatic niche formation and cell proliferation in bone lesions. Moreover, preclinical evidence of antitumoral effects of BPs will be presented and results from the most important clinical trials will be described critically. BPs may clearly play a clinically important role in early breast cancer in a postmenopausal adjuvant setting." @default.
- W2105393912 created "2016-06-24" @default.
- W2105393912 creator A5003744289 @default.
- W2105393912 creator A5008719596 @default.
- W2105393912 creator A5011919076 @default.
- W2105393912 creator A5013144248 @default.
- W2105393912 creator A5021735327 @default.
- W2105393912 creator A5029788016 @default.
- W2105393912 creator A5035261012 @default.
- W2105393912 creator A5059367989 @default.
- W2105393912 creator A5068836613 @default.
- W2105393912 creator A5075514238 @default.
- W2105393912 creator A5081202080 @default.
- W2105393912 creator A5091765229 @default.
- W2105393912 date "2015-09-02" @default.
- W2105393912 modified "2023-10-17" @default.
- W2105393912 title "Bisphosphonates as anticancer agents in early breast cancer: preclinical and clinical evidence" @default.
- W2105393912 cites W1495945591 @default.
- W2105393912 cites W1880057253 @default.
- W2105393912 cites W1938796902 @default.
- W2105393912 cites W1947874101 @default.
- W2105393912 cites W1965570423 @default.
- W2105393912 cites W1982915376 @default.
- W2105393912 cites W1983473247 @default.
- W2105393912 cites W1985727076 @default.
- W2105393912 cites W1985760249 @default.
- W2105393912 cites W1995840759 @default.
- W2105393912 cites W2003213153 @default.
- W2105393912 cites W2006825597 @default.
- W2105393912 cites W2007001439 @default.
- W2105393912 cites W2013107571 @default.
- W2105393912 cites W2026290443 @default.
- W2105393912 cites W2041868422 @default.
- W2105393912 cites W2045031638 @default.
- W2105393912 cites W2046829925 @default.
- W2105393912 cites W2054923667 @default.
- W2105393912 cites W2067509900 @default.
- W2105393912 cites W2068503417 @default.
- W2105393912 cites W2068530253 @default.
- W2105393912 cites W2073380111 @default.
- W2105393912 cites W2076412866 @default.
- W2105393912 cites W2078354251 @default.
- W2105393912 cites W2081839216 @default.
- W2105393912 cites W2090832878 @default.
- W2105393912 cites W2092491985 @default.
- W2105393912 cites W2100251610 @default.
- W2105393912 cites W2104032698 @default.
- W2105393912 cites W2104872826 @default.
- W2105393912 cites W2121015279 @default.
- W2105393912 cites W2125014991 @default.
- W2105393912 cites W2126357214 @default.
- W2105393912 cites W2127286421 @default.
- W2105393912 cites W2138067032 @default.
- W2105393912 cites W2141815918 @default.
- W2105393912 cites W2142421083 @default.
- W2105393912 cites W2143939516 @default.
- W2105393912 cites W2144860907 @default.
- W2105393912 cites W2148096512 @default.
- W2105393912 cites W2148378495 @default.
- W2105393912 cites W2150449240 @default.
- W2105393912 cites W2150601004 @default.
- W2105393912 cites W2153657104 @default.
- W2105393912 cites W2153711239 @default.
- W2105393912 cites W2154403560 @default.
- W2105393912 cites W2154720522 @default.
- W2105393912 cites W2155937162 @default.
- W2105393912 cites W2156683343 @default.
- W2105393912 cites W2159436449 @default.
- W2105393912 cites W2163949875 @default.
- W2105393912 cites W2172170054 @default.
- W2105393912 cites W2186929477 @default.
- W2105393912 cites W2599204719 @default.
- W2105393912 cites W3012557015 @default.
- W2105393912 cites W4210331534 @default.
- W2105393912 cites W4242024627 @default.
- W2105393912 doi "https://doi.org/10.1186/s13058-015-0634-8" @default.
- W2105393912 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4557314" @default.
- W2105393912 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26328589" @default.
- W2105393912 hasPublicationYear "2015" @default.
- W2105393912 type Work @default.
- W2105393912 sameAs 2105393912 @default.
- W2105393912 citedByCount "26" @default.
- W2105393912 countsByYear W21053939122016 @default.
- W2105393912 countsByYear W21053939122017 @default.
- W2105393912 countsByYear W21053939122018 @default.
- W2105393912 countsByYear W21053939122019 @default.
- W2105393912 countsByYear W21053939122020 @default.
- W2105393912 countsByYear W21053939122021 @default.
- W2105393912 countsByYear W21053939122022 @default.
- W2105393912 countsByYear W21053939122023 @default.
- W2105393912 crossrefType "journal-article" @default.
- W2105393912 hasAuthorship W2105393912A5003744289 @default.
- W2105393912 hasAuthorship W2105393912A5008719596 @default.
- W2105393912 hasAuthorship W2105393912A5011919076 @default.
- W2105393912 hasAuthorship W2105393912A5013144248 @default.
- W2105393912 hasAuthorship W2105393912A5021735327 @default.
- W2105393912 hasAuthorship W2105393912A5029788016 @default.
- W2105393912 hasAuthorship W2105393912A5035261012 @default.
- W2105393912 hasAuthorship W2105393912A5059367989 @default.
- W2105393912 hasAuthorship W2105393912A5068836613 @default.