FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2105397580> ?p ?o ?g. }

• W2105397580 abstract "The CCR5 gene encodes one of the major human immunodeficiency virus type 1 (HIV-1) coreceptors. A 32-bp deletion in this gene (delta ccr5) is associated with relative resistance to disease progression in heterozygous HIV-1-infected persons. The effect of this mutation on virologic and immunologic parameters was determined in a cohort of 45 perinatally HIV-1-infected children prospectively followed after 5 years of age. At a median age of 8.3 years, heterozygous children had significantly lower virus load than homozygous children (median, 3.3 vs. 4.1 log copies/mL, P < .009) and higher percentages of CD4 T cells (median, 26% vs. 17%, P < .07). However, there was no discernible influence of the CCR5 genotype on the percentages of CD8 T cells (P < .27) or on HIV-specific cytotoxic T lymphocyte activities (P < .65). There was a trend for lower rates of progression to AIDS (CDC stage C) in heterozygous children. These data confirm a major role for the CCR5 coreceptor in HIV-1 pathogenesis in children." @default.
• W2105397580 created "2016-06-24" @default.
• W2105397580 creator A5027866615 @default.
• W2105397580 creator A5035724583 @default.
• W2105397580 creator A5038687789 @default.
• W2105397580 creator A5045000319 @default.
• W2105397580 creator A5051621566 @default.
• W2105397580 creator A5057634158 @default.
• W2105397580 creator A5063105861 @default.
• W2105397580 creator A5063808208 @default.
• W2105397580 creator A5064920781 @default.
• W2105397580 creator A5090409232 @default.
• W2105397580 date "1998-10-01" @default.
• W2105397580 modified "2023-10-15" @default.
• W2105397580 title "Impact of Heterozygosity for the Chemokine Receptor CCR5 32‐bp‐Deleted Allele on Plasma Virus Load and CD4 T Lymphocytes in Perinatally Human Immunodeficiency Virus‐Infected Children at 8 Years of Age" @default.
• W2105397580 cites W1664573657 @default.
• W2105397580 cites W1789164989 @default.
• W2105397580 cites W1963984954 @default.
• W2105397580 cites W1965019797 @default.
• W2105397580 cites W1981440980 @default.
• W2105397580 cites W1981644527 @default.
• W2105397580 cites W1989035987 @default.
• W2105397580 cites W1991676347 @default.
• W2105397580 cites W1996183144 @default.
• W2105397580 cites W2007021820 @default.
• W2105397580 cites W2021932640 @default.
• W2105397580 cites W2033928634 @default.
• W2105397580 cites W2062148688 @default.
• W2105397580 cites W2063023106 @default.
• W2105397580 cites W2080350299 @default.
• W2105397580 cites W2082737563 @default.
• W2105397580 cites W2085724830 @default.
• W2105397580 cites W2088287053 @default.
• W2105397580 cites W2088874312 @default.
• W2105397580 cites W2108256128 @default.
• W2105397580 cites W2131376910 @default.
• W2105397580 cites W2149579640 @default.
• W2105397580 cites W2149663244 @default.
• W2105397580 cites W2168905701 @default.
• W2105397580 cites W2418336253 @default.
• W2105397580 cites W36895208 @default.
• W2105397580 doi "https://doi.org/10.1086/515660" @default.
• W2105397580 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9806029" @default.
• W2105397580 hasPublicationYear "1998" @default.
• W2105397580 type Work @default.
• W2105397580 sameAs 2105397580 @default.
• W2105397580 citedByCount "47" @default.
• W2105397580 countsByYear W21053975802012 @default.
• W2105397580 countsByYear W21053975802013 @default.
• W2105397580 countsByYear W21053975802015 @default.
• W2105397580 countsByYear W21053975802017 @default.
• W2105397580 countsByYear W21053975802018 @default.
• W2105397580 crossrefType "journal-article" @default.
• W2105397580 hasAuthorship W2105397580A5027866615 @default.
• W2105397580 hasAuthorship W2105397580A5035724583 @default.
• W2105397580 hasAuthorship W2105397580A5038687789 @default.
• W2105397580 hasAuthorship W2105397580A5045000319 @default.
• W2105397580 hasAuthorship W2105397580A5051621566 @default.
• W2105397580 hasAuthorship W2105397580A5057634158 @default.
• W2105397580 hasAuthorship W2105397580A5063105861 @default.
• W2105397580 hasAuthorship W2105397580A5063808208 @default.
• W2105397580 hasAuthorship W2105397580A5064920781 @default.
• W2105397580 hasAuthorship W2105397580A5090409232 @default.
• W2105397580 hasBestOaLocation W21053975801 @default.
• W2105397580 hasConcept C104317684 @default.
• W2105397580 hasConcept C12823836 @default.
• W2105397580 hasConcept C13373296 @default.
• W2105397580 hasConcept C135763542 @default.
• W2105397580 hasConcept C142462285 @default.
• W2105397580 hasConcept C143589142 @default.
• W2105397580 hasConcept C159047783 @default.
• W2105397580 hasConcept C167672396 @default.
• W2105397580 hasConcept C180754005 @default.
• W2105397580 hasConcept C203014093 @default.
• W2105397580 hasConcept C2522874641 @default.
• W2105397580 hasConcept C2776452011 @default.
• W2105397580 hasConcept C2779690655 @default.
• W2105397580 hasConcept C2780727368 @default.
• W2105397580 hasConcept C2780942790 @default.
• W2105397580 hasConcept C45635710 @default.
• W2105397580 hasConcept C54355233 @default.
• W2105397580 hasConcept C86803240 @default.
• W2105397580 hasConcept C8891405 @default.
• W2105397580 hasConceptScore W2105397580C104317684 @default.
• W2105397580 hasConceptScore W2105397580C12823836 @default.
• W2105397580 hasConceptScore W2105397580C13373296 @default.
• W2105397580 hasConceptScore W2105397580C135763542 @default.
• W2105397580 hasConceptScore W2105397580C142462285 @default.
• W2105397580 hasConceptScore W2105397580C143589142 @default.
• W2105397580 hasConceptScore W2105397580C159047783 @default.
• W2105397580 hasConceptScore W2105397580C167672396 @default.
• W2105397580 hasConceptScore W2105397580C180754005 @default.
• W2105397580 hasConceptScore W2105397580C203014093 @default.
• W2105397580 hasConceptScore W2105397580C2522874641 @default.
• W2105397580 hasConceptScore W2105397580C2776452011 @default.
• W2105397580 hasConceptScore W2105397580C2779690655 @default.
• W2105397580 hasConceptScore W2105397580C2780727368 @default.
• W2105397580 hasConceptScore W2105397580C2780942790 @default.
• W2105397580 hasConceptScore W2105397580C45635710 @default.
• W2105397580 hasConceptScore W2105397580C54355233 @default.

• next