FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2105440994> ?p ?o ?g. }

• W2105440994 endingPage "1726" @default.
• W2105440994 startingPage "1719" @default.
• W2105440994 abstract "Glutathione is an important natural tripeptide mainly used because of its antioxidative properties. Commercial glutathione is microbially synthesized by yeasts and the growing demand requires the development of new production strains. An adaptive laboratory evolution strategy using acrolein as a selection agent was employed to obtain strains with an enhanced glutathione accumulation phenotype accompanied by an acrolein resistance phenotype. Two particularly interesting isolates were obtained: one with a high volumetric productivity for glutathione reaching 8.3 mg(glutathione)/L h, which is twice as high as the volumetric productivity of its parental strain. This strain reached an elevated intracellular glutathione content of 3.9%. A second isolate with an even higher acrolein tolerance exhibited a lower volumetric productivity of 5.8 mg(glutathione)/L h due to a growth phenotype. However, this evolved strain accumulated glutathione in 3.3-fold higher concentration compared to its parental strain and reached a particularly high glutathione content of almost 6%. The presented results demonstrate that acrolein is a powerful selection agent to obtain high glutathione accumulation strains in an adaptive laboratory evolution experiment." @default.
• W2105440994 created "2016-06-24" @default.
• W2105440994 creator A5002153940 @default.
• W2105440994 creator A5021155987 @default.
• W2105440994 creator A5046460477 @default.
• W2105440994 creator A5048402796 @default.
• W2105440994 creator A5050115274 @default.
• W2105440994 creator A5062330182 @default.
• W2105440994 date "2015-05-26" @default.
• W2105440994 modified "2023-09-24" @default.
• W2105440994 title "Enhanced glutathione production by evolutionary engineering of <i>Saccharomyces cerevisiae</i> strains" @default.
• W2105440994 cites W1838774522 @default.
• W2105440994 cites W1858024074 @default.
• W2105440994 cites W1979379297 @default.
• W2105440994 cites W1987196385 @default.
• W2105440994 cites W1998853178 @default.
• W2105440994 cites W2006690337 @default.
• W2105440994 cites W2027945470 @default.
• W2105440994 cites W2030072720 @default.
• W2105440994 cites W2034848996 @default.
• W2105440994 cites W2062766197 @default.
• W2105440994 cites W2066831198 @default.
• W2105440994 cites W2069518894 @default.
• W2105440994 cites W2082062618 @default.
• W2105440994 cites W2094076114 @default.
• W2105440994 cites W2096258216 @default.
• W2105440994 cites W2114270359 @default.
• W2105440994 cites W2115941371 @default.
• W2105440994 cites W2119059442 @default.
• W2105440994 cites W2133568950 @default.
• W2105440994 cites W2156931352 @default.
• W2105440994 cites W2161000162 @default.
• W2105440994 cites W92313992 @default.
• W2105440994 doi "https://doi.org/10.1002/biot.201400809" @default.
• W2105440994 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25914400" @default.
• W2105440994 hasPublicationYear "2015" @default.
• W2105440994 type Work @default.
• W2105440994 sameAs 2105440994 @default.
• W2105440994 citedByCount "30" @default.
• W2105440994 countsByYear W21054409942015 @default.
• W2105440994 countsByYear W21054409942016 @default.
• W2105440994 countsByYear W21054409942017 @default.
• W2105440994 countsByYear W21054409942018 @default.
• W2105440994 countsByYear W21054409942019 @default.
• W2105440994 countsByYear W21054409942020 @default.
• W2105440994 countsByYear W21054409942021 @default.
• W2105440994 countsByYear W21054409942022 @default.
• W2105440994 countsByYear W21054409942023 @default.
• W2105440994 crossrefType "journal-article" @default.
• W2105440994 hasAuthorship W2105440994A5002153940 @default.
• W2105440994 hasAuthorship W2105440994A5021155987 @default.
• W2105440994 hasAuthorship W2105440994A5046460477 @default.
• W2105440994 hasAuthorship W2105440994A5048402796 @default.
• W2105440994 hasAuthorship W2105440994A5050115274 @default.
• W2105440994 hasAuthorship W2105440994A5062330182 @default.
• W2105440994 hasConcept C104317684 @default.
• W2105440994 hasConcept C105702510 @default.
• W2105440994 hasConcept C127716648 @default.
• W2105440994 hasConcept C161790260 @default.
• W2105440994 hasConcept C167392928 @default.
• W2105440994 hasConcept C181199279 @default.
• W2105440994 hasConcept C185592680 @default.
• W2105440994 hasConcept C2777576037 @default.
• W2105440994 hasConcept C2778022156 @default.
• W2105440994 hasConcept C2779222958 @default.
• W2105440994 hasConcept C2780422782 @default.
• W2105440994 hasConcept C515207424 @default.
• W2105440994 hasConcept C538909803 @default.
• W2105440994 hasConcept C55493867 @default.
• W2105440994 hasConcept C86803240 @default.
• W2105440994 hasConceptScore W2105440994C104317684 @default.
• W2105440994 hasConceptScore W2105440994C105702510 @default.
• W2105440994 hasConceptScore W2105440994C127716648 @default.
• W2105440994 hasConceptScore W2105440994C161790260 @default.
• W2105440994 hasConceptScore W2105440994C167392928 @default.
• W2105440994 hasConceptScore W2105440994C181199279 @default.
• W2105440994 hasConceptScore W2105440994C185592680 @default.
• W2105440994 hasConceptScore W2105440994C2777576037 @default.
• W2105440994 hasConceptScore W2105440994C2778022156 @default.
• W2105440994 hasConceptScore W2105440994C2779222958 @default.
• W2105440994 hasConceptScore W2105440994C2780422782 @default.
• W2105440994 hasConceptScore W2105440994C515207424 @default.
• W2105440994 hasConceptScore W2105440994C538909803 @default.
• W2105440994 hasConceptScore W2105440994C55493867 @default.
• W2105440994 hasConceptScore W2105440994C86803240 @default.
• W2105440994 hasFunder F4320323031 @default.
• W2105440994 hasIssue "11" @default.
• W2105440994 hasLocation W21054409941 @default.
• W2105440994 hasLocation W21054409942 @default.
• W2105440994 hasOpenAccess W2105440994 @default.
• W2105440994 hasPrimaryLocation W21054409941 @default.
• W2105440994 hasRelatedWork W1753932900 @default.
• W2105440994 hasRelatedWork W1977021374 @default.
• W2105440994 hasRelatedWork W2029793439 @default.
• W2105440994 hasRelatedWork W2110234289 @default.
• W2105440994 hasRelatedWork W2116005407 @default.
• W2105440994 hasRelatedWork W2378635774 @default.
• W2105440994 hasRelatedWork W2388645123 @default.

• next