Matches in SemOpenAlex for { <https://semopenalex.org/work/W2105448443> ?p ?o ?g. }
- W2105448443 endingPage "699" @default.
- W2105448443 startingPage "689" @default.
- W2105448443 abstract "Abstract: Donor‐specific antibodies (DSA) form a significant barrier in solid organ transplantation of highly pre‐sensitized candidates. Although avoiding transplantation over a positive cross‐match test can largely prevent the occurrence of hyperacute antibody‐mediated rejection, transplantation of highly pre‐sensitized candidates is often complicated by the occurrence of acute and chronic antibody‐mediated graft rejection leading to diminished graft function and survival. The pre‐existent HLA and/or non‐HLA‐specific antibodies are without any doubt important contributing factors underlying humoral‐mediated graft injury. Furthermore, increasing evidence underlines the association of newly formed de novo DSA after transplantation with poor graft function and survival. There is still a need to further develop desensitizing therapies not only to make transplantation of highly pre‐sensitized candidates feasible, but also to reduce the new formation of allo‐antibodies. Here, we summarize current views on desensitization therapies and the impact of the presence of DSA on the fate of the kidney graft." @default.
- W2105448443 created "2016-06-24" @default.
- W2105448443 creator A5041133240 @default.
- W2105448443 creator A5077226244 @default.
- W2105448443 creator A5090883710 @default.
- W2105448443 creator A5091458149 @default.
- W2105448443 date "2008-11-01" @default.
- W2105448443 modified "2023-10-11" @default.
- W2105448443 title "Humoral immunity in renal transplantation: clinical significance and therapeutic approach" @default.
- W2105448443 cites W1538362536 @default.
- W2105448443 cites W1560633215 @default.
- W2105448443 cites W1592986484 @default.
- W2105448443 cites W1964180982 @default.
- W2105448443 cites W1966509356 @default.
- W2105448443 cites W1968094833 @default.
- W2105448443 cites W1971278669 @default.
- W2105448443 cites W1973385524 @default.
- W2105448443 cites W1976694455 @default.
- W2105448443 cites W1978358597 @default.
- W2105448443 cites W1978925768 @default.
- W2105448443 cites W1980073060 @default.
- W2105448443 cites W1986037486 @default.
- W2105448443 cites W1987235930 @default.
- W2105448443 cites W1991668324 @default.
- W2105448443 cites W1992563074 @default.
- W2105448443 cites W1994624792 @default.
- W2105448443 cites W1996611927 @default.
- W2105448443 cites W1997244864 @default.
- W2105448443 cites W1998522073 @default.
- W2105448443 cites W2003798082 @default.
- W2105448443 cites W2006326109 @default.
- W2105448443 cites W2007350320 @default.
- W2105448443 cites W2011890445 @default.
- W2105448443 cites W2014955040 @default.
- W2105448443 cites W2016280339 @default.
- W2105448443 cites W2018523148 @default.
- W2105448443 cites W2021005241 @default.
- W2105448443 cites W2023377972 @default.
- W2105448443 cites W2026637830 @default.
- W2105448443 cites W2028913335 @default.
- W2105448443 cites W2037803467 @default.
- W2105448443 cites W2038604784 @default.
- W2105448443 cites W2041288261 @default.
- W2105448443 cites W2041331235 @default.
- W2105448443 cites W2045251171 @default.
- W2105448443 cites W2046944378 @default.
- W2105448443 cites W2049529636 @default.
- W2105448443 cites W2051679452 @default.
- W2105448443 cites W2053465471 @default.
- W2105448443 cites W2054928751 @default.
- W2105448443 cites W2057629807 @default.
- W2105448443 cites W2060214204 @default.
- W2105448443 cites W2061830778 @default.
- W2105448443 cites W2063150510 @default.
- W2105448443 cites W2066654039 @default.
- W2105448443 cites W2067811565 @default.
- W2105448443 cites W2068957613 @default.
- W2105448443 cites W2070487938 @default.
- W2105448443 cites W2071895538 @default.
- W2105448443 cites W2075061197 @default.
- W2105448443 cites W2076529461 @default.
- W2105448443 cites W2077890795 @default.
- W2105448443 cites W2078846149 @default.
- W2105448443 cites W2083435697 @default.
- W2105448443 cites W2085127178 @default.
- W2105448443 cites W2086494068 @default.
- W2105448443 cites W2087543590 @default.
- W2105448443 cites W2089290166 @default.
- W2105448443 cites W2089398667 @default.
- W2105448443 cites W2092072237 @default.
- W2105448443 cites W2094473847 @default.
- W2105448443 cites W2095678963 @default.
- W2105448443 cites W2096600563 @default.
- W2105448443 cites W2097293181 @default.
- W2105448443 cites W2099801548 @default.
- W2105448443 cites W2104343945 @default.
- W2105448443 cites W2110079652 @default.
- W2105448443 cites W2110348760 @default.
- W2105448443 cites W2111257586 @default.
- W2105448443 cites W2113653347 @default.
- W2105448443 cites W2114891247 @default.
- W2105448443 cites W2115045605 @default.
- W2105448443 cites W2115980401 @default.
- W2105448443 cites W2116476586 @default.
- W2105448443 cites W2118475498 @default.
- W2105448443 cites W2118493727 @default.
- W2105448443 cites W2122083735 @default.
- W2105448443 cites W2130820062 @default.
- W2105448443 cites W2131708234 @default.
- W2105448443 cites W2139609147 @default.
- W2105448443 cites W2144784671 @default.
- W2105448443 cites W2145188316 @default.
- W2105448443 cites W2147382630 @default.
- W2105448443 cites W2153266666 @default.
- W2105448443 cites W2154901790 @default.
- W2105448443 cites W2157381851 @default.
- W2105448443 cites W2161045147 @default.
- W2105448443 cites W2161379171 @default.