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- W2105487622 abstract "Migraine patients present increased risks of vascular diseases such as high blood pressure, insulin resistance, metabolic syndrome, stroke and coronary heart disease. Oxidative stress (OS) is increasingly being studied in relation to the pathophysiology of migraine, stimulated by the described association with the most frequent migraine comorbidities. Because many of the gene-encoded players of the OS balance are characterized by functional polymorphisms, it is supposed that the individual genomic profile could affect susceptibility to OS and to related pathophysiological conditions. This study aimed to characterize a panel of 10 polymorphisms in 8 OS-related genes in a chronic migraine (CM) population and healthy controls, to recognize a genetic risk in the process of migraine chronification. The sample consisted of 45 healthy women and 96 women diagnosed with CM. No deviations from the Hardy-Weinberg equilibrium were detected, or in the overall population, or in the CM group or in the control group." @default.
- W2105487622 created "2016-06-24" @default.
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- W2105487622 creator A5035469274 @default.
- W2105487622 creator A5053801851 @default.
- W2105487622 creator A5065178874 @default.
- W2105487622 date "2015-01-14" @default.
- W2105487622 modified "2023-10-15" @default.
- W2105487622 title "Lack of association between oxidative stress-related gene polymorphisms and chronic migraine in an Italian population" @default.
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- W2105487622 doi "https://doi.org/10.1586/14737175.2015.1001748" @default.
- W2105487622 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25585507" @default.
- W2105487622 hasPublicationYear "2015" @default.
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