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- W2105492846 abstract "Hb Southampton (also known as Hb Casper) is characterized by the substitution of a leucine residue for a proline at codon β106 (CTG→CCG). This mutation breaks the G helix and severely distorts the tertiary structure of the molecule, producing an unstable hemoglobin (Hb) and severe hemolysis. We identified this hemoglobinopathy in a young patient with severe hemolytic anemia and hepatosplenomegaly." @default.
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- W2105492846 date "2006-01-01" @default.
- W2105492846 modified "2023-10-18" @default.
- W2105492846 title "Hb Southampton [β106(G8)Leu→Pro, C<i>T</i>G→C<i>C</i>G] in an Argentinean Boy" @default.
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- W2105492846 doi "https://doi.org/10.1080/03630260600755930" @default.
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