FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2105508603> ?p ?o ?g. }

• W2105508603 endingPage "e10932" @default.
• W2105508603 startingPage "e10932" @default.
• W2105508603 abstract "Clostridium perfringens enterotoxin (encoded by the cpe gene) contributes to several important human, and possibly veterinary, enteric diseases. The current study investigated whether cpe locus organization in type C or D isolates resembles one of the three (one chromosomal and two plasmid-borne) cpe loci commonly found amongst type A isolates. Multiplex PCR assays capable of detecting sequences in those type A cpe loci failed to amplify products from cpe-positive type C and D isolates, indicating these isolates possess different cpe locus arrangements. Therefore, restriction fragments containing the cpe gene were cloned and sequenced from two type C isolates and one type D isolate. The obtained cpe locus sequences were then used to construct an overlapping PCR assay to assess cpe locus diversity amongst other cpe-positive type C and D isolates. All seven surveyed cpe-positive type C isolates had a plasmid-borne cpe locus partially resembling the cpe locus of type A isolates carrying a chromosomal cpe gene. In contrast, all eight type D isolates shared the same plasmid-borne cpe locus, which differed substantially from the cpe locus present in other C. perfringens by containing two copies of an ORF with 67% identity to a transposase gene (COG4644) found in Tn1546, but not previously associated with the cpe gene. These results identify greater diversity amongst cpe locus organization than previously appreciated, providing new insights into cpe locus evolution. Finally, evidence for cpe gene mobilization was found for both type C and D isolates, which could explain their cpe plasmid diversity." @default.
• W2105508603 created "2016-06-24" @default.
• W2105508603 creator A5010898507 @default.
• W2105508603 creator A5070793093 @default.
• W2105508603 creator A5074555871 @default.
• W2105508603 creator A5089450547 @default.
• W2105508603 date "2010-06-03" @default.
• W2105508603 modified "2023-09-26" @default.
• W2105508603 title "Organization of the cpe Locus in CPE-Positive Clostridium perfringens Type C and D Isolates" @default.
• W2105508603 cites W1486649516 @default.
• W2105508603 cites W1542705459 @default.
• W2105508603 cites W1933260492 @default.
• W2105508603 cites W1966777133 @default.
• W2105508603 cites W1977892595 @default.
• W2105508603 cites W2041848175 @default.
• W2105508603 cites W2052199264 @default.
• W2105508603 cites W2064557781 @default.
• W2105508603 cites W2069431460 @default.
• W2105508603 cites W2087762882 @default.
• W2105508603 cites W2089483355 @default.
• W2105508603 cites W2100368223 @default.
• W2105508603 cites W2104606186 @default.
• W2105508603 cites W2106418680 @default.
• W2105508603 cites W2107906266 @default.
• W2105508603 cites W2110235981 @default.
• W2105508603 cites W2114196688 @default.
• W2105508603 cites W2115810316 @default.
• W2105508603 cites W2116598668 @default.
• W2105508603 cites W2119262069 @default.
• W2105508603 cites W2119530493 @default.
• W2105508603 cites W2120268627 @default.
• W2105508603 cites W2126028658 @default.
• W2105508603 cites W2127653170 @default.
• W2105508603 cites W2136842053 @default.
• W2105508603 cites W2137446111 @default.
• W2105508603 cites W2142697899 @default.
• W2105508603 cites W2145584773 @default.
• W2105508603 cites W2149062789 @default.
• W2105508603 cites W2149753744 @default.
• W2105508603 cites W2156168744 @default.
• W2105508603 cites W2165115357 @default.
• W2105508603 cites W2169071688 @default.
• W2105508603 cites W2324607028 @default.
• W2105508603 doi "https://doi.org/10.1371/journal.pone.0010932" @default.
• W2105508603 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2880595" @default.
• W2105508603 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20532170" @default.
• W2105508603 hasPublicationYear "2010" @default.
• W2105508603 type Work @default.
• W2105508603 sameAs 2105508603 @default.
• W2105508603 citedByCount "26" @default.
• W2105508603 countsByYear W21055086032012 @default.
• W2105508603 countsByYear W21055086032013 @default.
• W2105508603 countsByYear W21055086032014 @default.
• W2105508603 countsByYear W21055086032015 @default.
• W2105508603 countsByYear W21055086032016 @default.
• W2105508603 countsByYear W21055086032018 @default.
• W2105508603 countsByYear W21055086032019 @default.
• W2105508603 countsByYear W21055086032020 @default.
• W2105508603 countsByYear W21055086032021 @default.
• W2105508603 countsByYear W21055086032022 @default.
• W2105508603 countsByYear W21055086032023 @default.
• W2105508603 crossrefType "journal-article" @default.
• W2105508603 hasAuthorship W2105508603A5010898507 @default.
• W2105508603 hasAuthorship W2105508603A5070793093 @default.
• W2105508603 hasAuthorship W2105508603A5074555871 @default.
• W2105508603 hasAuthorship W2105508603A5089450547 @default.
• W2105508603 hasBestOaLocation W21055086031 @default.
• W2105508603 hasConcept C104317684 @default.
• W2105508603 hasConcept C22744801 @default.
• W2105508603 hasConcept C2779116991 @default.
• W2105508603 hasConcept C49105822 @default.
• W2105508603 hasConcept C523546767 @default.
• W2105508603 hasConcept C54355233 @default.
• W2105508603 hasConcept C84597430 @default.
• W2105508603 hasConcept C86803240 @default.
• W2105508603 hasConcept C89423630 @default.
• W2105508603 hasConcept C90583042 @default.
• W2105508603 hasConceptScore W2105508603C104317684 @default.
• W2105508603 hasConceptScore W2105508603C22744801 @default.
• W2105508603 hasConceptScore W2105508603C2779116991 @default.
• W2105508603 hasConceptScore W2105508603C49105822 @default.
• W2105508603 hasConceptScore W2105508603C523546767 @default.
• W2105508603 hasConceptScore W2105508603C54355233 @default.
• W2105508603 hasConceptScore W2105508603C84597430 @default.
• W2105508603 hasConceptScore W2105508603C86803240 @default.
• W2105508603 hasConceptScore W2105508603C89423630 @default.
• W2105508603 hasConceptScore W2105508603C90583042 @default.
• W2105508603 hasIssue "6" @default.
• W2105508603 hasLocation W21055086031 @default.
• W2105508603 hasLocation W21055086032 @default.
• W2105508603 hasLocation W21055086033 @default.
• W2105508603 hasLocation W21055086034 @default.
• W2105508603 hasLocation W21055086035 @default.
• W2105508603 hasOpenAccess W2105508603 @default.
• W2105508603 hasPrimaryLocation W21055086031 @default.
• W2105508603 hasRelatedWork W1571771606 @default.
• W2105508603 hasRelatedWork W1828691184 @default.
• W2105508603 hasRelatedWork W1886625688 @default.

• next