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- W2105512489 abstract "Temperature gradient gel electrophoresis (TGGE) and related methods can separate DNA fragments that differ by a single base pair or defect. This article describes the basic features of TGGE, and reviews the theoretical model of DNA unwinding and its ability to predict DNA mobility in a temperature gradient gel. Recent applications of TGGE and related methods that were directed at detecting point mutations, and evaluating the effects of single site defects are also reported." @default.
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- W2105512489 date "1998-05-01" @default.
- W2105512489 modified "2023-10-10" @default.
- W2105512489 title "Detecting single base substitutions, mismatches and bulges in DNA by temperature gradient gel electrophoresis and related methods" @default.
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- W2105512489 doi "https://doi.org/10.1016/s0021-9673(98)00149-6" @default.
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