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• W2105521787 abstract "This study was designed to prospectively investigate the efficacy and cognitive adverse effects of stereotactic bilateral anterior cingulotomy as a treatment for refractory obsessive-compulsive (OCD) patients for 12 months.Patients were eligible if they had severe OCD and rigorous treatments had been unsuccessful. Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Clinical Global Impression (CGI) and neuropsychological tests were used to assess the efficacy and cognitive changes of cingulotomy before and 12 months after operation.The mean improvement rate of the Y-BOCS scores achieved from baseline was 36.0%. Out of 14 patients six met responder criteria; 35% or higher improvement rate on Y-BOCS and CGI improvement of very much or much better at 12-month follow-up. There was no significant cognitive dysfunction after cingulotomy.Anterior cingulotomy shows few cognitive adverse effects, with about half of the OCD patients demonstrating significant symptomatic improvement." @default.
• W2105521787 created "2016-06-24" @default.
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• W2105521787 date "2003-03-27" @default.
• W2105521787 modified "2023-10-17" @default.
• W2105521787 title "Anterior cingulotomy for refractory obsessive-compulsive disorder" @default.
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• W2105521787 doi "https://doi.org/10.1034/j.1600-0447.2003.00087.x" @default.
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