Matches in SemOpenAlex for { <https://semopenalex.org/work/W2105558855> ?p ?o ?g. }
- W2105558855 endingPage "13636" @default.
- W2105558855 startingPage "13627" @default.
- W2105558855 abstract "ABSTRACT Computational and biological approaches were undertaken to characterize the role of the human astrovirus nonstructural protein nsP1a/4, located at the C-terminal fragment of nsP1a. Computer analysis reveals sequence similarities to other nonstructural viral proteins involved in RNA replication and/or transcription and allows the identification of a glutamine- and proline-rich region, the prediction of many phosphorylation and O-glycosylation sites, and the occurrence of a KKXX-like endoplasmic reticulum retention signal. Immunoprecipitation analysis with an antibody against a synthetic peptide of the nsP1a/4 sequence detected polyprotein precursors of 160, 75, and 38 to 40 kDa as well as five smaller proteins in the range of 21 to 27 kDa. Immunofluorescence labeling showed that the nsP1a/4 protein is accumulated at the perinuclear region, in association with the endoplasmic reticulum and the viral RNA. These results suggest the involvement of nsP1a/4 protein in the RNA replication process in endoplasmic reticulum-derived intracellular membranes." @default.
- W2105558855 created "2016-06-24" @default.
- W2105558855 creator A5025261666 @default.
- W2105558855 creator A5074521300 @default.
- W2105558855 creator A5086259786 @default.
- W2105558855 creator A5090897438 @default.
- W2105558855 date "2004-12-15" @default.
- W2105558855 modified "2023-10-13" @default.
- W2105558855 title "C-Terminal nsP1a Protein of Human Astrovirus Colocalizes with the Endoplasmic Reticulum and Viral RNA" @default.
- W2105558855 cites W1482767536 @default.
- W2105558855 cites W1508800810 @default.
- W2105558855 cites W1541022484 @default.
- W2105558855 cites W1595673144 @default.
- W2105558855 cites W1723843641 @default.
- W2105558855 cites W1735561674 @default.
- W2105558855 cites W1762084525 @default.
- W2105558855 cites W1791702149 @default.
- W2105558855 cites W1818479639 @default.
- W2105558855 cites W1907806866 @default.
- W2105558855 cites W1920378431 @default.
- W2105558855 cites W1957867949 @default.
- W2105558855 cites W1965144201 @default.
- W2105558855 cites W1969864109 @default.
- W2105558855 cites W1974719543 @default.
- W2105558855 cites W1980219499 @default.
- W2105558855 cites W1993290654 @default.
- W2105558855 cites W1998495837 @default.
- W2105558855 cites W2001115857 @default.
- W2105558855 cites W2008068385 @default.
- W2105558855 cites W2008399824 @default.
- W2105558855 cites W2010822247 @default.
- W2105558855 cites W2014892069 @default.
- W2105558855 cites W2020183125 @default.
- W2105558855 cites W2023332774 @default.
- W2105558855 cites W2038163496 @default.
- W2105558855 cites W2049050714 @default.
- W2105558855 cites W2050690072 @default.
- W2105558855 cites W2053418558 @default.
- W2105558855 cites W2079074163 @default.
- W2105558855 cites W2079232213 @default.
- W2105558855 cites W2081849195 @default.
- W2105558855 cites W2084466582 @default.
- W2105558855 cites W2085206941 @default.
- W2105558855 cites W2087064593 @default.
- W2105558855 cites W2094127705 @default.
- W2105558855 cites W2099946731 @default.
- W2105558855 cites W2106039034 @default.
- W2105558855 cites W2106882534 @default.
- W2105558855 cites W2107566186 @default.
- W2105558855 cites W2108660849 @default.
- W2105558855 cites W2112704704 @default.
- W2105558855 cites W2114126592 @default.
- W2105558855 cites W2118892564 @default.
- W2105558855 cites W2129965627 @default.
- W2105558855 cites W2131344097 @default.
- W2105558855 cites W2140557481 @default.
- W2105558855 cites W2141503209 @default.
- W2105558855 cites W2148066741 @default.
- W2105558855 cites W2156522253 @default.
- W2105558855 cites W2163868178 @default.
- W2105558855 cites W2164739739 @default.
- W2105558855 cites W2166629953 @default.
- W2105558855 cites W2167754234 @default.
- W2105558855 cites W2170215368 @default.
- W2105558855 cites W2226647378 @default.
- W2105558855 cites W2285978083 @default.
- W2105558855 cites W2916193864 @default.
- W2105558855 cites W4243228481 @default.
- W2105558855 doi "https://doi.org/10.1128/jvi.78.24.13627-13636.2004" @default.
- W2105558855 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/533902" @default.
- W2105558855 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15564473" @default.
- W2105558855 hasPublicationYear "2004" @default.
- W2105558855 type Work @default.
- W2105558855 sameAs 2105558855 @default.
- W2105558855 citedByCount "44" @default.
- W2105558855 countsByYear W21055588552012 @default.
- W2105558855 countsByYear W21055588552013 @default.
- W2105558855 countsByYear W21055588552014 @default.
- W2105558855 countsByYear W21055588552015 @default.
- W2105558855 countsByYear W21055588552016 @default.
- W2105558855 countsByYear W21055588552017 @default.
- W2105558855 countsByYear W21055588552018 @default.
- W2105558855 countsByYear W21055588552019 @default.
- W2105558855 countsByYear W21055588552020 @default.
- W2105558855 countsByYear W21055588552021 @default.
- W2105558855 countsByYear W21055588552022 @default.
- W2105558855 countsByYear W21055588552023 @default.
- W2105558855 crossrefType "journal-article" @default.
- W2105558855 hasAuthorship W2105558855A5025261666 @default.
- W2105558855 hasAuthorship W2105558855A5074521300 @default.
- W2105558855 hasAuthorship W2105558855A5086259786 @default.
- W2105558855 hasAuthorship W2105558855A5090897438 @default.
- W2105558855 hasBestOaLocation W21055588551 @default.
- W2105558855 hasConcept C104317684 @default.
- W2105558855 hasConcept C10858879 @default.
- W2105558855 hasConcept C153911025 @default.
- W2105558855 hasConcept C158617107 @default.
- W2105558855 hasConcept C162740809 @default.