FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2105616482> ?p ?o ?g. }

• W2105616482 endingPage "492" @default.
• W2105616482 startingPage "481" @default.
• W2105616482 abstract "1. Gastric motility and neurotransmitter release in response to vagal stimulation were studied using a vascularly isolated perfused rat stomach. Gastric motor responses were recorded by a strain gauge force transducer implanted on the proximal stomach. 2. Electrical stimulation of vagal trunk (0.5-20 Hz) produced a triphasic response which was composed of a rapid transient relaxation (first phase) followed by a phasic contraction (second phase) and a delayed prolonged relaxation (third phase). Maximum responses of the first, second and third phase were observed at 2.5, 5 and 10 Hz, respectively. Intra-arterial infusion of tetrodotoxin (0.1 microM) or hexamethonium (100 microM) completely abolished the triphasic response. 3. The nitric oxide (NO) biosynthesis inhibitor NG-nitro-L-arginine (L-NNA; 100 microM) significantly antagonized the rapid relaxation but had no effect on the delayed relaxation, while vasoactive intestinal polypeptide (VIP) antagonist (1 microM) significantly reduced the delayed relaxation without affecting the rapid relaxation. 4. In response to vagal stimulation, NO production ([3H]citrulline formation in gastric tissue preloaded with [3H]arginine) was maximum at 2.5 Hz, whereas VIP release into the venous effluent was largest at 10 Hz. Hexamethonium abolished vagal-stimulated NO production and VIP release. L-NNA had no effect on VIP release in response to vagal stimulation. 5. The nicotinic receptor agonist 1,1-dimethyl-4-phenylpiperizinium (DMPP; 100 microM) also caused a triphasic response similar to that observed with vagal stimulation and produced a significant increase in VIP and NO formation. DMPP-evoked VIP release was not affected by L-NNA. Similarly, DMPP-evoked NO production was not antagonized by VIP antagonist. 6. These results suggest that vagus nerve stimulation evokes NO and VIP release via nicotinic synapses which cause different modes of relaxation of the stomach. There is no interaction between NO and VIP release in response to vagal stimulation." @default.
• W2105616482 created "2016-06-24" @default.
• W2105616482 creator A5023526632 @default.
• W2105616482 creator A5086272334 @default.
• W2105616482 date "1995-04-15" @default.
• W2105616482 modified "2023-10-18" @default.
• W2105616482 title "Vagal control of nitric oxide and vasoactive intestinal polypeptide release in the regulation of gastric relaxation in rat." @default.
• W2105616482 cites W146615651 @default.
• W2105616482 cites W1486626431 @default.
• W2105616482 cites W1561385461 @default.
• W2105616482 cites W1715841309 @default.
• W2105616482 cites W1966322594 @default.
• W2105616482 cites W1966733094 @default.
• W2105616482 cites W1976572358 @default.
• W2105616482 cites W1978062669 @default.
• W2105616482 cites W1982321188 @default.
• W2105616482 cites W1986674917 @default.
• W2105616482 cites W1992234383 @default.
• W2105616482 cites W1992718978 @default.
• W2105616482 cites W1994632633 @default.
• W2105616482 cites W1996709911 @default.
• W2105616482 cites W1998016976 @default.
• W2105616482 cites W2006675249 @default.
• W2105616482 cites W2013086524 @default.
• W2105616482 cites W2020013537 @default.
• W2105616482 cites W2026981844 @default.
• W2105616482 cites W2031029466 @default.
• W2105616482 cites W2040934798 @default.
• W2105616482 cites W2042865941 @default.
• W2105616482 cites W2051031104 @default.
• W2105616482 cites W2051871841 @default.
• W2105616482 cites W2057975848 @default.
• W2105616482 cites W2058423368 @default.
• W2105616482 cites W2061882884 @default.
• W2105616482 cites W2064433058 @default.
• W2105616482 cites W2082435849 @default.
• W2105616482 cites W2085996595 @default.
• W2105616482 cites W2088388072 @default.
• W2105616482 cites W2089790709 @default.
• W2105616482 cites W2093912965 @default.
• W2105616482 cites W2128635872 @default.
• W2105616482 cites W2147802001 @default.
• W2105616482 cites W2166100895 @default.
• W2105616482 cites W2167023752 @default.
• W2105616482 cites W2246284382 @default.
• W2105616482 cites W2276199432 @default.
• W2105616482 cites W2278300840 @default.
• W2105616482 cites W2288780669 @default.
• W2105616482 cites W2340483209 @default.
• W2105616482 cites W2340705612 @default.
• W2105616482 cites W2409368196 @default.
• W2105616482 cites W2417930383 @default.
• W2105616482 doi "https://doi.org/10.1113/jphysiol.1995.sp020680" @default.
• W2105616482 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1157909" @default.
• W2105616482 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7602539" @default.
• W2105616482 hasPublicationYear "1995" @default.
• W2105616482 type Work @default.
• W2105616482 sameAs 2105616482 @default.
• W2105616482 citedByCount "142" @default.
• W2105616482 countsByYear W21056164822012 @default.
• W2105616482 countsByYear W21056164822013 @default.
• W2105616482 countsByYear W21056164822014 @default.
• W2105616482 countsByYear W21056164822015 @default.
• W2105616482 countsByYear W21056164822016 @default.
• W2105616482 countsByYear W21056164822017 @default.
• W2105616482 countsByYear W21056164822018 @default.
• W2105616482 countsByYear W21056164822019 @default.
• W2105616482 countsByYear W21056164822020 @default.
• W2105616482 countsByYear W21056164822021 @default.
• W2105616482 countsByYear W21056164822023 @default.
• W2105616482 crossrefType "journal-article" @default.
• W2105616482 hasAuthorship W2105616482A5023526632 @default.
• W2105616482 hasAuthorship W2105616482A5086272334 @default.
• W2105616482 hasBestOaLocation W21056164822 @default.
• W2105616482 hasConcept C118303440 @default.
• W2105616482 hasConcept C126322002 @default.
• W2105616482 hasConcept C134018914 @default.
• W2105616482 hasConcept C170493617 @default.
• W2105616482 hasConcept C185592680 @default.
• W2105616482 hasConcept C24998067 @default.
• W2105616482 hasConcept C2775893369 @default.
• W2105616482 hasConcept C2776741303 @default.
• W2105616482 hasConcept C2781404750 @default.
• W2105616482 hasConcept C519581460 @default.
• W2105616482 hasConcept C71924100 @default.
• W2105616482 hasConcept C8330315 @default.
• W2105616482 hasConceptScore W2105616482C118303440 @default.
• W2105616482 hasConceptScore W2105616482C126322002 @default.
• W2105616482 hasConceptScore W2105616482C134018914 @default.
• W2105616482 hasConceptScore W2105616482C170493617 @default.
• W2105616482 hasConceptScore W2105616482C185592680 @default.
• W2105616482 hasConceptScore W2105616482C24998067 @default.
• W2105616482 hasConceptScore W2105616482C2775893369 @default.
• W2105616482 hasConceptScore W2105616482C2776741303 @default.
• W2105616482 hasConceptScore W2105616482C2781404750 @default.
• W2105616482 hasConceptScore W2105616482C519581460 @default.
• W2105616482 hasConceptScore W2105616482C71924100 @default.
• W2105616482 hasConceptScore W2105616482C8330315 @default.

• next