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- W2105628529 abstract "The present work was carried out with the purpose of evaluating the effect of β-cyclodextrin (β-CD), sodium lauryl sulfate (SLS) and polyethylene glycol 200 (PEG 200) on the solubilization of lamotrigine by means of phase-solublility studies and solubility prediction using Jouyban-Acree model. The experimental solubility values of various mixtures were fitted to the equation and fitting accuracy of solubility data to this model was evaluated. A quantitative relationship between the solubilizing agents was assessed and the predictive accuracy of the Jouyban-Acree model and its applicability assuring reliable prediction of the model in binary systems was studied. The significance of the simultaneous presence of SLS and β-CD on lamotrigine solubility was studied in binary solvent mixture." @default.
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- W2105628529 date "2016-01-01" @default.
- W2105628529 modified "2023-09-25" @default.
- W2105628529 title "Co-solubilization of Lamotrigine by Complexation and Micellization in Binary Solvent Mixtures" @default.
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- W2105628529 doi "https://doi.org/10.1016/j.cherd.2015.10.037" @default.
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