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• W2105658758 abstract "Tumor progression and pregnancy share many common features, such as immune tolerance and invasion. The invasion of trophoblasts in the placenta into the uterine wall is essential for fetal development, and is thus precisely regulated. Its deregulation has been implicated in preeclampsia, a leading cause for maternal and perinatal mortality and morbidity. Pathogenesis of preeclampsia remains to be defined. Microarray-based gene profiling has been widely used for identifying genes responsible for preeclampsia. In this review, we have summarized the recent data from the microarray studies with preeclamptic placentas. Despite the complex of gene signatures, suggestive of the heterogeneity of preeclampsia, these studies identified a number of differentially expressed genes associated with preeclampsia. Interestingly, most of them have been reported to be tightly involved in tumor progression. We have discussed these interesting genes and analyzed their potential molecular functions in preeclampsia, compared with their roles in malignancy development. Further investigations are warranted to explore the involvement in molecular network of each identified gene, which may provide not only novel strategies for prevention and therapy for preeclampsia but also a better understanding of cancer cells. The trophoblastic cells, with their capacity for proliferation and differentiation, apoptosis and survival, migration, angiogenesis and immune modulation by exploiting similar molecular pathways, make them a compelling model for cancer research." @default.
• W2105658758 created "2016-06-24" @default.
• W2105658758 creator A5030649015 @default.
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• W2105658758 creator A5064606841 @default.
• W2105658758 creator A5085682207 @default.
• W2105658758 date "2012-08-23" @default.
• W2105658758 modified "2023-10-13" @default.
• W2105658758 title "A lesson for cancer research: placental microarray gene analysis in preeclampsia" @default.
• W2105658758 cites W1523234270 @default.
• W2105658758 cites W1590112381 @default.
• W2105658758 cites W1809465031 @default.
• W2105658758 cites W1834505123 @default.
• W2105658758 cites W1838162872 @default.
• W2105658758 cites W1852534842 @default.
• W2105658758 cites W1926131824 @default.
• W2105658758 cites W1965098283 @default.
• W2105658758 cites W1965273919 @default.
• W2105658758 cites W1966930760 @default.
• W2105658758 cites W1970624991 @default.
• W2105658758 cites W1973093171 @default.
• W2105658758 cites W1975868044 @default.
• W2105658758 cites W1978591675 @default.
• W2105658758 cites W1984970610 @default.
• W2105658758 cites W1985804036 @default.
• W2105658758 cites W1986469266 @default.
• W2105658758 cites W1989978684 @default.
• W2105658758 cites W1992338344 @default.
• W2105658758 cites W1996191588 @default.
• W2105658758 cites W2000561567 @default.
• W2105658758 cites W2003608352 @default.
• W2105658758 cites W2003774981 @default.
• W2105658758 cites W2004067791 @default.
• W2105658758 cites W2005104217 @default.
• W2105658758 cites W2006885289 @default.
• W2105658758 cites W2008919922 @default.
• W2105658758 cites W2009172514 @default.
• W2105658758 cites W2010098090 @default.
• W2105658758 cites W2013558300 @default.
• W2105658758 cites W2016294374 @default.
• W2105658758 cites W2016956768 @default.
• W2105658758 cites W2017771409 @default.
• W2105658758 cites W2022431559 @default.
• W2105658758 cites W2022648554 @default.
• W2105658758 cites W2023509793 @default.
• W2105658758 cites W2024678567 @default.
• W2105658758 cites W2025499382 @default.
• W2105658758 cites W2026038921 @default.
• W2105658758 cites W2026196936 @default.
• W2105658758 cites W2028369131 @default.
• W2105658758 cites W2032095810 @default.
• W2105658758 cites W2032882287 @default.
• W2105658758 cites W2034511793 @default.
• W2105658758 cites W2035307313 @default.
• W2105658758 cites W2035483520 @default.
• W2105658758 cites W2035653659 @default.
• W2105658758 cites W2036469757 @default.
• W2105658758 cites W2040772454 @default.
• W2105658758 cites W2045287901 @default.
• W2105658758 cites W2047331757 @default.
• W2105658758 cites W2047844588 @default.
• W2105658758 cites W2048865153 @default.
• W2105658758 cites W2050087753 @default.
• W2105658758 cites W2054633892 @default.
• W2105658758 cites W2054684209 @default.
• W2105658758 cites W2056331644 @default.
• W2105658758 cites W2056939983 @default.
• W2105658758 cites W2057428741 @default.
• W2105658758 cites W2057531505 @default.
• W2105658758 cites W2060141872 @default.
• W2105658758 cites W2067532738 @default.
• W2105658758 cites W2070446470 @default.
• W2105658758 cites W2072756039 @default.
• W2105658758 cites W2074938026 @default.
• W2105658758 cites W2076543297 @default.
• W2105658758 cites W2081734842 @default.
• W2105658758 cites W2085524373 @default.
• W2105658758 cites W2086073438 @default.
• W2105658758 cites W2091562897 @default.
• W2105658758 cites W2094967868 @default.
• W2105658758 cites W2100446922 @default.
• W2105658758 cites W2102298863 @default.
• W2105658758 cites W2104123431 @default.
• W2105658758 cites W2105076216 @default.
• W2105658758 cites W2105632053 @default.
• W2105658758 cites W2105918084 @default.
• W2105658758 cites W2107933989 @default.
• W2105658758 cites W2108224203 @default.
• W2105658758 cites W2109289772 @default.
• W2105658758 cites W2115435274 @default.
• W2105658758 cites W2115664813 @default.
• W2105658758 cites W2117692326 @default.
• W2105658758 cites W2118475119 @default.
• W2105658758 cites W2118840886 @default.
• W2105658758 cites W2119519672 @default.
• W2105658758 cites W2120062423 @default.
• W2105658758 cites W2125742006 @default.

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