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- W2105660444 abstract "Hyperglycemia plays an important role in the pathogenesis of type 2 diabetes mellitus, i.e., glucotoxicity, and it also is the major risk factor for microvascular complications. Thus, effective glycemic control will not only reduce the incidence of microvascular complications but also correct some of the metabolic abnormalities that contribute to the progression of the disease. Achieving durable tight glycemic control is challenging because of progressive β-cell failure and is hampered by increased frequency of side effects, e.g., hypoglycemia and weight gain. Most recently, inhibitors of the renal sodium-glucose cotransporter have been developed to produce glucosuria and reduce the plasma glucose concentration. These oral antidiabetic agents have the potential to improve glycemic control while avoiding hypoglycemia, to correct the glucotoxicity, and to promote weight loss. In this review, we will summarize the available data concerning the mechanism of action, efficacy, and safety of this novel antidiabetic therapeutic approach." @default.
- W2105660444 created "2016-06-24" @default.
- W2105660444 creator A5005726509 @default.
- W2105660444 creator A5041583991 @default.
- W2105660444 date "2011-05-23" @default.
- W2105660444 modified "2023-10-09" @default.
- W2105660444 title "Role of Sodium-Glucose Cotransporter 2 (SGLT 2) Inhibitors in the Treatment of Type 2 Diabetes" @default.
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- W2105660444 cites W1963931057 @default.
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- W2105660444 cites W1983055281 @default.
- W2105660444 cites W1986117742 @default.
- W2105660444 cites W1992835945 @default.
- W2105660444 cites W1994768261 @default.
- W2105660444 cites W1997746154 @default.
- W2105660444 cites W2000047428 @default.
- W2105660444 cites W2002078774 @default.
- W2105660444 cites W2002760082 @default.
- W2105660444 cites W2003176723 @default.
- W2105660444 cites W2013766983 @default.
- W2105660444 cites W2026609170 @default.
- W2105660444 cites W2031484324 @default.
- W2105660444 cites W2038961236 @default.
- W2105660444 cites W2039955263 @default.
- W2105660444 cites W2041780259 @default.
- W2105660444 cites W2046096086 @default.
- W2105660444 cites W2048870206 @default.
- W2105660444 cites W2054866483 @default.
- W2105660444 cites W2062351818 @default.
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- W2105660444 cites W2063169804 @default.
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- W2105660444 cites W2078992128 @default.
- W2105660444 cites W2086812198 @default.
- W2105660444 cites W2091203103 @default.
- W2105660444 cites W2092411706 @default.
- W2105660444 cites W2096329362 @default.
- W2105660444 cites W2100968639 @default.
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- W2105660444 cites W2126894905 @default.
- W2105660444 cites W2127833912 @default.
- W2105660444 cites W2130400490 @default.
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- W2105660444 cites W2159610388 @default.
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- W2105660444 cites W2337454357 @default.
- W2105660444 cites W2406992900 @default.
- W2105660444 cites W2411842944 @default.
- W2105660444 cites W2949977409 @default.
- W2105660444 cites W4210559565 @default.
- W2105660444 cites W4212888272 @default.
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- W2105660444 doi "https://doi.org/10.1210/er.2010-0029" @default.
- W2105660444 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21606218" @default.
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