FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2105701607> ?p ?o ?g. }

• W2105701607 endingPage "651" @default.
• W2105701607 startingPage "641" @default.
• W2105701607 abstract "We have previously reported that rehabilitative reaching training initiated 4 days following an incomplete cervical spinal cord injury (SCI) in adult rats promotes plasticity and task-specific recovery. This training, however, also resulted in impairments in an untrained task. Here we examined whether delaying the rehabilitative training following cervical SCI is still effective in promoting task-specific recovery, but circumvents impairments in an untrained task, comparable to what has been reported in stroke models. Therefore, reaching training for a period of 6 weeks was initiated at Day 12 following a cervical dorso-lateral quadrant lesion. Thereupon the rats' ability to reach and to walk on a horizontal ladder (i.e. the untrained task) was assessed, and 8 weeks post-injury cortical map changes were investigated through microstimulation. Further, we examined changes in phospho protein kinase A (pPKA) levels following an immediate and a delayed onset of reaching training in rats with cervical SCI. We found that delayed rehabilitative training was comparably effective as immediate training in promoting task-specific recovery and sprouting of injured axons. Importantly, delayed training did not impair the performance on horizontal ladder walking. Strikingly, only delayed reaching training restored cortical PKA levels that had dropped significantly over 2 weeks post-injury. Additionally, delayed training did not influence cortical map changes following injury, but decreased white matter damage. In conclusion, our results show that a short delay in the onset of training in a forelimb task significantly alters our outcome measures, which should be considered in future rehabilitative approaches." @default.
• W2105701607 created "2016-06-24" @default.
• W2105701607 creator A5017444728 @default.
• W2105701607 creator A5033934135 @default.
• W2105701607 creator A5039582437 @default.
• W2105701607 creator A5059924244 @default.
• W2105701607 creator A5075971611 @default.
• W2105701607 date "2009-02-01" @default.
• W2105701607 modified "2023-10-18" @default.
• W2105701607 title "Advantages of delaying the onset of rehabilitative reaching training in rats with incomplete spinal cord injury" @default.
• W2105701607 cites W1482711476 @default.
• W2105701607 cites W1889533143 @default.
• W2105701607 cites W1939467907 @default.
• W2105701607 cites W1967987243 @default.
• W2105701607 cites W1970087762 @default.
• W2105701607 cites W1973726191 @default.
• W2105701607 cites W1973862785 @default.
• W2105701607 cites W1977612666 @default.
• W2105701607 cites W1979645662 @default.
• W2105701607 cites W1980608838 @default.
• W2105701607 cites W1981333952 @default.
• W2105701607 cites W1983080207 @default.
• W2105701607 cites W1986878360 @default.
• W2105701607 cites W1987130960 @default.
• W2105701607 cites W1994770860 @default.
• W2105701607 cites W1998882825 @default.
• W2105701607 cites W1999618730 @default.
• W2105701607 cites W2001101139 @default.
• W2105701607 cites W2003381774 @default.
• W2105701607 cites W2008265159 @default.
• W2105701607 cites W2013402377 @default.
• W2105701607 cites W2021518416 @default.
• W2105701607 cites W2023053568 @default.
• W2105701607 cites W2029871266 @default.
• W2105701607 cites W2032323291 @default.
• W2105701607 cites W2035730645 @default.
• W2105701607 cites W2052440244 @default.
• W2105701607 cites W2053218399 @default.
• W2105701607 cites W2055187509 @default.
• W2105701607 cites W2055508174 @default.
• W2105701607 cites W2056712232 @default.
• W2105701607 cites W2060373786 @default.
• W2105701607 cites W2066013426 @default.
• W2105701607 cites W2070436191 @default.
• W2105701607 cites W2070545661 @default.
• W2105701607 cites W2070970988 @default.
• W2105701607 cites W2071872645 @default.
• W2105701607 cites W2075112177 @default.
• W2105701607 cites W2076016439 @default.
• W2105701607 cites W2076492394 @default.
• W2105701607 cites W2077739433 @default.
• W2105701607 cites W2082463733 @default.
• W2105701607 cites W2084357882 @default.
• W2105701607 cites W2084527441 @default.
• W2105701607 cites W2093203706 @default.
• W2105701607 cites W2094308504 @default.
• W2105701607 cites W2096816417 @default.
• W2105701607 cites W2096988407 @default.
• W2105701607 cites W2098995517 @default.
• W2105701607 cites W2103966320 @default.
• W2105701607 cites W2105598374 @default.
• W2105701607 cites W2109398572 @default.
• W2105701607 cites W2115028023 @default.
• W2105701607 cites W2124146923 @default.
• W2105701607 cites W2135094753 @default.
• W2105701607 cites W2141766263 @default.
• W2105701607 cites W2152786417 @default.
• W2105701607 cites W2159053023 @default.
• W2105701607 cites W2161475511 @default.
• W2105701607 cites W2171759509 @default.
• W2105701607 cites W2214569581 @default.
• W2105701607 cites W2256745758 @default.
• W2105701607 doi "https://doi.org/10.1111/j.1460-9568.2008.06600.x" @default.
• W2105701607 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19222562" @default.
• W2105701607 hasPublicationYear "2009" @default.
• W2105701607 type Work @default.
• W2105701607 sameAs 2105701607 @default.
• W2105701607 citedByCount "52" @default.
• W2105701607 countsByYear W21057016072012 @default.
• W2105701607 countsByYear W21057016072013 @default.
• W2105701607 countsByYear W21057016072014 @default.
• W2105701607 countsByYear W21057016072015 @default.
• W2105701607 countsByYear W21057016072016 @default.
• W2105701607 countsByYear W21057016072017 @default.
• W2105701607 countsByYear W21057016072018 @default.
• W2105701607 countsByYear W21057016072019 @default.
• W2105701607 countsByYear W21057016072020 @default.
• W2105701607 countsByYear W21057016072021 @default.
• W2105701607 countsByYear W21057016072022 @default.
• W2105701607 countsByYear W21057016072023 @default.
• W2105701607 crossrefType "journal-article" @default.
• W2105701607 hasAuthorship W2105701607A5017444728 @default.
• W2105701607 hasAuthorship W2105701607A5033934135 @default.
• W2105701607 hasAuthorship W2105701607A5039582437 @default.
• W2105701607 hasAuthorship W2105701607A5059924244 @default.
• W2105701607 hasAuthorship W2105701607A5075971611 @default.
• W2105701607 hasConcept C105702510 @default.
• W2105701607 hasConcept C115490710 @default.

• next