FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2105707953> ?p ?o ?g. }

• W2105707953 abstract "High grade soft tissue sarcomas often show histological invasion to adjacent compartment including bone and vessel. This study aimed to evaluate histological invasion in high grade soft tissue sarcomas, clarify its impact on prognosis and devise treatment strategies. We retrospectively reviewed 133 patients with non-small round cell high grade soft tissue sarcomas surgically treated between 2001 and 2011. Clinical and histological factors examined for prognostic value included age, gender, size, depth, location, adjuvant therapy and invasion to adjacent compartment. Study endpoints included overall survival rate, event free survival rate and local recurrence free survival rate, estimated by the Kaplan-Meier method. Univariate and multivariate analyses were performed using the log-rank test and Cox proportional hazards model. Local recurrence was recognized in 14 cases (11%). The 5-year overall survival rate and 5-year event free survival rate were 82.2% and 63.6% respectively. The metastasis-free survival rate at 5 years and local recurrence-free survival rate at 5 years were 69.8% and 86.8% respectively. Histological invasion to adjacent compartment was noted in 52 cases (39%), and was significantly correlated with histological type (p = 0.01), tumor size (p = 0.009), and depth (p < 0.05). In multivariate analyses, we showed that tumor size and histological invasion were significant independent predictors of OS (hazard ratio 8.1/2.5) and EFS (hazard ratio 5.5/2.2), while only tumor size was a significant independent predictor of LRFS (hazard ratio 4.0). We evaluated the relation between histological invasion and the oncological outcomes of high grade soft tissue sarcomas. In multivariate analyses, histological invasion was found to be an independent adverse prognostic factor with hazard ratios of 2.2-2.5, suggesting that a detailed assessment of these factors is essential. Histological invasion showed a correlation with tumor size and histological type, and the surgical margin should be decided based on these factors." @default.
• W2105707953 created "2016-06-24" @default.
• W2105707953 creator A5023589754 @default.
• W2105707953 creator A5027207215 @default.
• W2105707953 creator A5038827887 @default.
• W2105707953 creator A5054828220 @default.
• W2105707953 creator A5089659933 @default.
• W2105707953 date "2014-09-22" @default.
• W2105707953 modified "2023-09-27" @default.
• W2105707953 title "Prognostic significance of histological invasion in high grade soft tissue sarcomas" @default.
• W2105707953 cites W1584305089 @default.
• W2105707953 cites W1831255489 @default.
• W2105707953 cites W1862666273 @default.
• W2105707953 cites W1918248799 @default.
• W2105707953 cites W1971106078 @default.
• W2105707953 cites W1982355570 @default.
• W2105707953 cites W1983206829 @default.
• W2105707953 cites W2011170946 @default.
• W2105707953 cites W2034660548 @default.
• W2105707953 cites W2035348714 @default.
• W2105707953 cites W2040135111 @default.
• W2105707953 cites W2045383704 @default.
• W2105707953 cites W2056843329 @default.
• W2105707953 cites W2075485315 @default.
• W2105707953 cites W2077237731 @default.
• W2105707953 cites W2081229528 @default.
• W2105707953 cites W2089755974 @default.
• W2105707953 cites W2099653103 @default.
• W2105707953 cites W2104213181 @default.
• W2105707953 cites W2114774464 @default.
• W2105707953 cites W2139131750 @default.
• W2105707953 cites W2146604827 @default.
• W2105707953 cites W2170101119 @default.
• W2105707953 cites W4239498373 @default.
• W2105707953 doi "https://doi.org/10.1186/2193-1801-3-544" @default.
• W2105707953 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4179641" @default.
• W2105707953 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25279332" @default.
• W2105707953 hasPublicationYear "2014" @default.
• W2105707953 type Work @default.
• W2105707953 sameAs 2105707953 @default.
• W2105707953 citedByCount "16" @default.
• W2105707953 countsByYear W21057079532015 @default.
• W2105707953 countsByYear W21057079532016 @default.
• W2105707953 countsByYear W21057079532017 @default.
• W2105707953 countsByYear W21057079532018 @default.
• W2105707953 countsByYear W21057079532020 @default.
• W2105707953 countsByYear W21057079532021 @default.
• W2105707953 countsByYear W21057079532023 @default.
• W2105707953 crossrefType "journal-article" @default.
• W2105707953 hasAuthorship W2105707953A5023589754 @default.
• W2105707953 hasAuthorship W2105707953A5027207215 @default.
• W2105707953 hasAuthorship W2105707953A5038827887 @default.
• W2105707953 hasAuthorship W2105707953A5054828220 @default.
• W2105707953 hasAuthorship W2105707953A5089659933 @default.
• W2105707953 hasBestOaLocation W21057079531 @default.
• W2105707953 hasConcept C10515644 @default.
• W2105707953 hasConcept C126322002 @default.
• W2105707953 hasConcept C136948725 @default.
• W2105707953 hasConcept C142724271 @default.
• W2105707953 hasConcept C143998085 @default.
• W2105707953 hasConcept C144301174 @default.
• W2105707953 hasConcept C207103383 @default.
• W2105707953 hasConcept C2776283816 @default.
• W2105707953 hasConcept C3019894029 @default.
• W2105707953 hasConcept C38180746 @default.
• W2105707953 hasConcept C44249647 @default.
• W2105707953 hasConcept C50382708 @default.
• W2105707953 hasConcept C57742111 @default.
• W2105707953 hasConcept C66339696 @default.
• W2105707953 hasConcept C71924100 @default.
• W2105707953 hasConceptScore W2105707953C10515644 @default.
• W2105707953 hasConceptScore W2105707953C126322002 @default.
• W2105707953 hasConceptScore W2105707953C136948725 @default.
• W2105707953 hasConceptScore W2105707953C142724271 @default.
• W2105707953 hasConceptScore W2105707953C143998085 @default.
• W2105707953 hasConceptScore W2105707953C144301174 @default.
• W2105707953 hasConceptScore W2105707953C207103383 @default.
• W2105707953 hasConceptScore W2105707953C2776283816 @default.
• W2105707953 hasConceptScore W2105707953C3019894029 @default.
• W2105707953 hasConceptScore W2105707953C38180746 @default.
• W2105707953 hasConceptScore W2105707953C44249647 @default.
• W2105707953 hasConceptScore W2105707953C50382708 @default.
• W2105707953 hasConceptScore W2105707953C57742111 @default.
• W2105707953 hasConceptScore W2105707953C66339696 @default.
• W2105707953 hasConceptScore W2105707953C71924100 @default.
• W2105707953 hasIssue "1" @default.
• W2105707953 hasLocation W21057079531 @default.
• W2105707953 hasLocation W21057079532 @default.
• W2105707953 hasLocation W21057079533 @default.
• W2105707953 hasLocation W21057079534 @default.
• W2105707953 hasOpenAccess W2105707953 @default.
• W2105707953 hasPrimaryLocation W21057079531 @default.
• W2105707953 hasRelatedWork W2096525432 @default.
• W2105707953 hasRelatedWork W2138506229 @default.
• W2105707953 hasRelatedWork W2357428483 @default.
• W2105707953 hasRelatedWork W2378171567 @default.
• W2105707953 hasRelatedWork W2390704523 @default.
• W2105707953 hasRelatedWork W2392151514 @default.
• W2105707953 hasRelatedWork W2395438194 @default.
• W2105707953 hasRelatedWork W2751913398 @default.

• next