FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2105777827> ?p ?o ?g. }

• W2105777827 endingPage "405" @default.
• W2105777827 startingPage "401" @default.
• W2105777827 abstract "Human leukocyte antigens (HLA) play an important role in presenting virus antigens to immune cells that are responsible for the clearance of virus-infected cells and tumor cells. Herein, we evaluated whether genetic variants of HLA-DP and HLA-DQ are associated with cervical cancer risk.We genotyped four single nucleotide polymorphisms (SNPs) in HLA-DP (rs3077 and rs9277535) and HLA-DQ (rs2856718 and rs7453920) in a two-stage case-control study with a total of 2317 cervical cancer cases and 2109 cancer-free controls using TaqMan allelic discrimination assay.We found consistently significant associations of HLA-DP rs3077 and rs9277535 with increased risks of cervical cancer (dominant genetic model: adjusted OR=1.51, 95% CI=1.32-1.71 for rs3077; adjusted OR=1.29, 95% CI=1.12-1.49 for rs9277535). When combining the effects of HLA-DP rs3077 and rs9277535, subjects carrying ≥1 variant alleles had a 1.55-fold increased risk of cervical cancer (95% CI=1.32-1.81), compared with those carrying 0 variant allele. And cervical cancer risk significantly increased with the increasing number of variant alleles of the two SNPs in a dose-dependent manner (P for trend=4.33×10(-10)). However, there were no significant associations for HLA-DQ rs2856718 and rs7453920 in our population.These findings indicate that HLA-DP rs3077 and rs9277535 were candidate susceptibility markers for cervical cancer in Chinese females. Further validation studies with different ethnic background, biological function analyses and especially HPV typing together were needed." @default.
• W2105777827 created "2016-06-24" @default.
• W2105777827 creator A5001453048 @default.
• W2105777827 creator A5003850660 @default.
• W2105777827 creator A5006295324 @default.
• W2105777827 creator A5007704456 @default.
• W2105777827 creator A5012266709 @default.
• W2105777827 creator A5013744029 @default.
• W2105777827 creator A5017486433 @default.
• W2105777827 creator A5023250695 @default.
• W2105777827 creator A5029418945 @default.
• W2105777827 creator A5041948410 @default.
• W2105777827 creator A5050585924 @default.
• W2105777827 creator A5063481044 @default.
• W2105777827 creator A5068093752 @default.
• W2105777827 creator A5072024057 @default.
• W2105777827 creator A5078720822 @default.
• W2105777827 creator A5084213516 @default.
• W2105777827 date "2013-05-01" @default.
• W2105777827 modified "2023-09-23" @default.
• W2105777827 title "Genetic variants in HLA-DP/DQ contribute to risk of cervical cancer: A two-stage study in Chinese women" @default.
• W2105777827 cites W1973624321 @default.
• W2105777827 cites W1977223394 @default.
• W2105777827 cites W1985359926 @default.
• W2105777827 cites W1987350137 @default.
• W2105777827 cites W1988647224 @default.
• W2105777827 cites W2005654652 @default.
• W2105777827 cites W2009382271 @default.
• W2105777827 cites W2021438212 @default.
• W2105777827 cites W2024595202 @default.
• W2105777827 cites W2039906679 @default.
• W2105777827 cites W2044833878 @default.
• W2105777827 cites W2050673484 @default.
• W2105777827 cites W2083514525 @default.
• W2105777827 cites W2094025727 @default.
• W2105777827 cites W2094529863 @default.
• W2105777827 cites W2095353668 @default.
• W2105777827 cites W2095976339 @default.
• W2105777827 cites W2098765233 @default.
• W2105777827 cites W2106787323 @default.
• W2105777827 cites W2130726794 @default.
• W2105777827 cites W2134844770 @default.
• W2105777827 cites W2141921059 @default.
• W2105777827 cites W2145009181 @default.
• W2105777827 cites W2146193487 @default.
• W2105777827 cites W2161489192 @default.
• W2105777827 cites W2162565737 @default.
• W2105777827 cites W2166615931 @default.
• W2105777827 cites W2330204815 @default.
• W2105777827 cites W3143504308 @default.
• W2105777827 cites W4362208337 @default.
• W2105777827 doi "https://doi.org/10.1016/j.ygyno.2013.02.017" @default.
• W2105777827 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23428460" @default.
• W2105777827 hasPublicationYear "2013" @default.
• W2105777827 type Work @default.
• W2105777827 sameAs 2105777827 @default.
• W2105777827 citedByCount "17" @default.
• W2105777827 countsByYear W21057778272013 @default.
• W2105777827 countsByYear W21057778272014 @default.
• W2105777827 countsByYear W21057778272015 @default.
• W2105777827 countsByYear W21057778272016 @default.
• W2105777827 countsByYear W21057778272017 @default.
• W2105777827 countsByYear W21057778272018 @default.
• W2105777827 countsByYear W21057778272020 @default.
• W2105777827 countsByYear W21057778272021 @default.
• W2105777827 countsByYear W21057778272023 @default.
• W2105777827 crossrefType "journal-article" @default.
• W2105777827 hasAuthorship W2105777827A5001453048 @default.
• W2105777827 hasAuthorship W2105777827A5003850660 @default.
• W2105777827 hasAuthorship W2105777827A5006295324 @default.
• W2105777827 hasAuthorship W2105777827A5007704456 @default.
• W2105777827 hasAuthorship W2105777827A5012266709 @default.
• W2105777827 hasAuthorship W2105777827A5013744029 @default.
• W2105777827 hasAuthorship W2105777827A5017486433 @default.
• W2105777827 hasAuthorship W2105777827A5023250695 @default.
• W2105777827 hasAuthorship W2105777827A5029418945 @default.
• W2105777827 hasAuthorship W2105777827A5041948410 @default.
• W2105777827 hasAuthorship W2105777827A5050585924 @default.
• W2105777827 hasAuthorship W2105777827A5063481044 @default.
• W2105777827 hasAuthorship W2105777827A5068093752 @default.
• W2105777827 hasAuthorship W2105777827A5072024057 @default.
• W2105777827 hasAuthorship W2105777827A5078720822 @default.
• W2105777827 hasAuthorship W2105777827A5084213516 @default.
• W2105777827 hasConcept C104317684 @default.
• W2105777827 hasConcept C121608353 @default.
• W2105777827 hasConcept C126322002 @default.
• W2105777827 hasConcept C135763542 @default.
• W2105777827 hasConcept C143998085 @default.
• W2105777827 hasConcept C147483822 @default.
• W2105777827 hasConcept C153209595 @default.
• W2105777827 hasConcept C180754005 @default.
• W2105777827 hasConcept C188280979 @default.
• W2105777827 hasConcept C203014093 @default.
• W2105777827 hasConcept C2778220009 @default.
• W2105777827 hasConcept C2908647359 @default.
• W2105777827 hasConcept C54355233 @default.
• W2105777827 hasConcept C71924100 @default.
• W2105777827 hasConcept C86803240 @default.

• next