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- W2105832491 endingPage "416" @default.
- W2105832491 startingPage "401" @default.
- W2105832491 abstract "The authors review current research on the safety and tolerability of anticonvulsant medications used for individuals over the age of 60 years with affective disorders, agitation and other psychiatric disorders. Three anticonvulsants currently approved in the US for treatment of bipolar affective disorder are reviewed: valproate, lamotrigine and extended-release carbamazepine. The authors discuss the pharmacokinetics, pharmacodynamics, drug–drug interactions and the impact of ageing for each drug. There are few studies of anticonvulsant medications in elderly patients with bipolar disorder or other psychiatric conditions. Therefore, the authors summarise adverse events of greatest prevalence and/or greatest severity based on data derived predominately from studies of geriatric patients with epilepsy and/or other non-psychiatric indications. Guidelines are offered for the safe use of these medications in the elderly, based on research literature." @default.
- W2105832491 created "2016-06-24" @default.
- W2105832491 creator A5008363188 @default.
- W2105832491 creator A5037145712 @default.
- W2105832491 creator A5046547929 @default.
- W2105832491 creator A5059634453 @default.
- W2105832491 date "2006-04-13" @default.
- W2105832491 modified "2023-09-26" @default.
- W2105832491 title "Safety and tolerability of mood-stabilising anticonvulsants in the elderly" @default.
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