FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2105855231> ?p ?o ?g. }

• W2105855231 endingPage "591" @default.
• W2105855231 startingPage "579" @default.
• W2105855231 abstract "Background: Pollen from trees of the order Fagales are important allergen sources in most parts of the world. Clinical, immunochemical, and molecular biology studies indicate that they contain cross-reactive allergens. The major birch pollen allergen, Bet v 1, and birch profilin, Bet v 2, a highly cross-reactive allergen, have been cloned and expressed in Escherichia coli. Objective: The purpose of this study was to demonstrate the presence of allergens in Fagales pollens that share IgE epitopes with recombinant Bet v 1 and Bet v 2 and to determine the percentage of birch, alder, hornbeam, hazel, and oak pollen–specific IgE that can be preabsorbed with rBet v 1 and rBet v 2 from 102 sera of different populations of subjects allergic to Fagales tree pollen. Methods: The presence of rBet v 1– and rBet v 2–homologous allergens in tree pollen extracts was investigated by IgE immunoblot inhibition experiments, and the percentage of tree (birch, alder, hornbeam, hazel, and oak) pollen–specific IgE that was bound by a mixture of rBet v 1 and rBet v 2 was determined by RAST-based quantitative IgE inhibition experiments. The clinical significance of IgE antibody cross-reactivity was studied by skin prick testing with rBet v 1, rBet v 2, and Fagales pollen extracts. Results: Natural birch, alder, hornbeam, hazel, and oak pollen contain allergens that share IgE epitopes with rBet v 1 and rBet v 2. A combination of rBet v 1 and rBet v 2 accounted for 82% of tree pollen–specific IgE on average. Most of the tree pollen–specific IgE was directed against rBet v 1. Conclusion: rBet v 1 and rBet v 2 contain most of the Fagales pollen–specific IgE epitopes and may therefore substitute natural tree pollen extracts not only for diagnosis but also for patient-tailored immunotherapy of tree pollen allergy. (J Allergy Clin Immunol 1998;102:579-91.)" @default.
• W2105855231 created "2016-06-24" @default.
• W2105855231 creator A5010955441 @default.
• W2105855231 creator A5018719393 @default.
• W2105855231 creator A5025909718 @default.
• W2105855231 creator A5037217815 @default.
• W2105855231 creator A5043589158 @default.
• W2105855231 creator A5050048947 @default.
• W2105855231 creator A5054661531 @default.
• W2105855231 creator A5073115445 @default.
• W2105855231 date "1998-10-01" @default.
• W2105855231 modified "2023-09-30" @default.
• W2105855231 title "Recombinant birch pollen allergens (rBet v 1 and rBet v 2) contain most of the IgE epitopes present in birch, alder, hornbeam, hazel, and oak pollen: A quantitative IgE inhibition study with sera from different populations☆☆☆★★★" @default.
• W2105855231 cites W1668142298 @default.
• W2105855231 cites W1751860473 @default.
• W2105855231 cites W1968756485 @default.
• W2105855231 cites W1968801496 @default.
• W2105855231 cites W1970021701 @default.
• W2105855231 cites W1970672159 @default.
• W2105855231 cites W1978216986 @default.
• W2105855231 cites W1983065058 @default.
• W2105855231 cites W1984260844 @default.
• W2105855231 cites W1999811293 @default.
• W2105855231 cites W2000279446 @default.
• W2105855231 cites W2003902333 @default.
• W2105855231 cites W2004802511 @default.
• W2105855231 cites W2008848238 @default.
• W2105855231 cites W2008921531 @default.
• W2105855231 cites W2009048532 @default.
• W2105855231 cites W2011576536 @default.
• W2105855231 cites W2015425755 @default.
• W2105855231 cites W2018517200 @default.
• W2105855231 cites W2020170582 @default.
• W2105855231 cites W2021747766 @default.
• W2105855231 cites W2022103314 @default.
• W2105855231 cites W2022708664 @default.
• W2105855231 cites W2032611208 @default.
• W2105855231 cites W2047150341 @default.
• W2105855231 cites W2049465161 @default.
• W2105855231 cites W2051548814 @default.
• W2105855231 cites W2052233059 @default.
• W2105855231 cites W2053973011 @default.
• W2105855231 cites W2064519865 @default.
• W2105855231 cites W2065354034 @default.
• W2105855231 cites W2073352341 @default.
• W2105855231 cites W2076096345 @default.
• W2105855231 cites W2084636378 @default.
• W2105855231 cites W2089339054 @default.
• W2105855231 cites W2094943959 @default.
• W2105855231 cites W2100837269 @default.
• W2105855231 cites W2101108802 @default.
• W2105855231 cites W2103903862 @default.
• W2105855231 cites W2104289972 @default.
• W2105855231 cites W2105259124 @default.
• W2105855231 cites W2109593104 @default.
• W2105855231 cites W2128635872 @default.
• W2105855231 cites W2130886030 @default.
• W2105855231 cites W2137801310 @default.
• W2105855231 cites W2150200156 @default.
• W2105855231 cites W2151322766 @default.
• W2105855231 cites W2165029064 @default.
• W2105855231 cites W2168522749 @default.
• W2105855231 cites W2582398023 @default.
• W2105855231 cites W3133895878 @default.
• W2105855231 cites W3143776549 @default.
• W2105855231 cites W2460484988 @default.
• W2105855231 doi "https://doi.org/10.1016/s0091-6749(98)70273-8" @default.
• W2105855231 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9802365" @default.
• W2105855231 hasPublicationYear "1998" @default.
• W2105855231 type Work @default.
• W2105855231 sameAs 2105855231 @default.
• W2105855231 citedByCount "175" @default.
• W2105855231 countsByYear W21058552312012 @default.
• W2105855231 countsByYear W21058552312013 @default.
• W2105855231 countsByYear W21058552312014 @default.
• W2105855231 countsByYear W21058552312015 @default.
• W2105855231 countsByYear W21058552312016 @default.
• W2105855231 countsByYear W21058552312017 @default.
• W2105855231 countsByYear W21058552312018 @default.
• W2105855231 countsByYear W21058552312019 @default.
• W2105855231 countsByYear W21058552312020 @default.
• W2105855231 countsByYear W21058552312021 @default.
• W2105855231 countsByYear W21058552312022 @default.
• W2105855231 countsByYear W21058552312023 @default.
• W2105855231 crossrefType "journal-article" @default.
• W2105855231 hasAuthorship W2105855231A5010955441 @default.
• W2105855231 hasAuthorship W2105855231A5018719393 @default.
• W2105855231 hasAuthorship W2105855231A5025909718 @default.
• W2105855231 hasAuthorship W2105855231A5037217815 @default.
• W2105855231 hasAuthorship W2105855231A5043589158 @default.
• W2105855231 hasAuthorship W2105855231A5050048947 @default.
• W2105855231 hasAuthorship W2105855231A5054661531 @default.
• W2105855231 hasAuthorship W2105855231A5073115445 @default.
• W2105855231 hasConcept C141105273 @default.
• W2105855231 hasConcept C159654299 @default.
• W2105855231 hasConcept C203014093 @default.
• W2105855231 hasConcept C207480886 @default.
• W2105855231 hasConcept C2776500793 @default.

• next