FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2105863456> ?p ?o ?g. }

• W2105863456 endingPage "379" @default.
• W2105863456 startingPage "371" @default.
• W2105863456 abstract "Purpose:To evaluate in vivo a new drug-eluting biodegradable vascular stent with respect to biocompatibility, neointimal hyperplasia formation, and reliability. Methods:Self-expanding biodegradable poly-96L/4D-lactic acid (PLA) stents with 2 drugs (PLA + dexamethasone [DEX] and PLA + simvastatin [SIM]) and 2 different coatings (PLA + P(D,L)LA and PLA + polycaprolactone [PCL]) were compared with a self-expanding stainless steel Wallstent. The stents were implanted in both common iliac arteries of 8 pigs. Prior to sacrifice at 1 month, angiography was performed to determine patency. Specimens were harvested for quantitative histomorphometry; vascular injury and inflammation scores were assigned to the stented iliac segments. Results:All stented arteries were angiographically patent. The mean luminal diameter (3.05 mm) and area (30.36 mm2) of DEX-eluting PLA stents were decreased compared to other stents (PLA + P(D,L)LA: 3.66 mm and 43.92 mm2 PLA + SIM: 4.21 mm and 56.48 mm2 PLA + PCL: 4.19 mm and 54.64 mm2 Wallstent: 5.01 mm and 81.19 mm2). Wallstents and DEX-eluting PLA stents induced minimal intimal hyperplasia: PLA + DEX: 0.16 mm, PLA + P(D,L)LA: 0.35 mm, PLA + SIM: 0.33 mm, PLA + PCL: 0.29 mm, and Wallstent: 0.18 mm. The vascular injury scores demonstrated only mild vascular trauma for all stents. Only mild to moderate inflammatory reaction was noted around stent struts with a vascular inflammation score. Conclusions:Biodegradable polymer stents appear to be biocompatible and reliable, causing minimal neointimal hyperplasia. Furthermore, the new biodegradable poly-D/L-lactic acid stent can be used as a local drug delivery vehicle. The DEX-eluting PLA stent reduces neointimal hyperplasia. The findings show a need for further investigation to prove the efficacy and safety of this new biodegradable drug-eluting stent." @default.
• W2105863456 created "2016-06-24" @default.
• W2105863456 creator A5014623140 @default.
• W2105863456 creator A5023848489 @default.
• W2105863456 creator A5037820841 @default.
• W2105863456 creator A5051797910 @default.
• W2105863456 creator A5051968535 @default.
• W2105863456 creator A5057045778 @default.
• W2105863456 creator A5080250273 @default.
• W2105863456 creator A5083859158 @default.
• W2105863456 date "2005-06-01" @default.
• W2105863456 modified "2023-10-11" @default.
• W2105863456 title "<b>Drug-Eluting Biodegradable Poly-D/L-Lactic Acid Vascular Stents:</b>An Experimental Pilot Study" @default.
• W2105863456 cites W1490250650 @default.
• W2105863456 cites W162501764 @default.
• W2105863456 cites W1965139285 @default.
• W2105863456 cites W1978881081 @default.
• W2105863456 cites W1986858103 @default.
• W2105863456 cites W1995157123 @default.
• W2105863456 cites W2000105699 @default.
• W2105863456 cites W2003005498 @default.
• W2105863456 cites W2004473920 @default.
• W2105863456 cites W2007564058 @default.
• W2105863456 cites W2010094572 @default.
• W2105863456 cites W2015070193 @default.
• W2105863456 cites W2020906145 @default.
• W2105863456 cites W2032881237 @default.
• W2105863456 cites W2061672125 @default.
• W2105863456 cites W2069465511 @default.
• W2105863456 cites W2074919956 @default.
• W2105863456 cites W2079818105 @default.
• W2105863456 cites W2081554071 @default.
• W2105863456 cites W2082667344 @default.
• W2105863456 cites W2083630382 @default.
• W2105863456 cites W2086716664 @default.
• W2105863456 cites W2087713847 @default.
• W2105863456 cites W2089696104 @default.
• W2105863456 cites W2094202003 @default.
• W2105863456 cites W2102374129 @default.
• W2105863456 cites W2110352874 @default.
• W2105863456 cites W2135227814 @default.
• W2105863456 cites W2140025564 @default.
• W2105863456 cites W2146249767 @default.
• W2105863456 cites W2149898702 @default.
• W2105863456 cites W2154503508 @default.
• W2105863456 cites W2166932054 @default.
• W2105863456 cites W2169000150 @default.
• W2105863456 cites W2324489407 @default.
• W2105863456 cites W2910748611 @default.
• W2105863456 cites W4234610775 @default.
• W2105863456 cites W76422404 @default.
• W2105863456 doi "https://doi.org/10.1583/05-1525.1" @default.
• W2105863456 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15943514" @default.
• W2105863456 hasPublicationYear "2005" @default.
• W2105863456 type Work @default.
• W2105863456 sameAs 2105863456 @default.
• W2105863456 citedByCount "60" @default.
• W2105863456 countsByYear W21058634562012 @default.
• W2105863456 countsByYear W21058634562013 @default.
• W2105863456 countsByYear W21058634562014 @default.
• W2105863456 countsByYear W21058634562015 @default.
• W2105863456 countsByYear W21058634562017 @default.
• W2105863456 countsByYear W21058634562018 @default.
• W2105863456 countsByYear W21058634562019 @default.
• W2105863456 countsByYear W21058634562021 @default.
• W2105863456 countsByYear W21058634562022 @default.
• W2105863456 crossrefType "journal-article" @default.
• W2105863456 hasAuthorship W2105863456A5014623140 @default.
• W2105863456 hasAuthorship W2105863456A5023848489 @default.
• W2105863456 hasAuthorship W2105863456A5037820841 @default.
• W2105863456 hasAuthorship W2105863456A5051797910 @default.
• W2105863456 hasAuthorship W2105863456A5051968535 @default.
• W2105863456 hasAuthorship W2105863456A5057045778 @default.
• W2105863456 hasAuthorship W2105863456A5080250273 @default.
• W2105863456 hasAuthorship W2105863456A5083859158 @default.
• W2105863456 hasConcept C126322002 @default.
• W2105863456 hasConcept C126838900 @default.
• W2105863456 hasConcept C126894567 @default.
• W2105863456 hasConcept C141071460 @default.
• W2105863456 hasConcept C150903083 @default.
• W2105863456 hasConcept C159985019 @default.
• W2105863456 hasConcept C191897082 @default.
• W2105863456 hasConcept C192562407 @default.
• W2105863456 hasConcept C207001950 @default.
• W2105863456 hasConcept C2777230088 @default.
• W2105863456 hasConcept C2777339539 @default.
• W2105863456 hasConcept C2778095995 @default.
• W2105863456 hasConcept C2778283817 @default.
• W2105863456 hasConcept C2778583881 @default.
• W2105863456 hasConcept C2779751240 @default.
• W2105863456 hasConcept C2780326628 @default.
• W2105863456 hasConcept C2992686903 @default.
• W2105863456 hasConcept C45211672 @default.
• W2105863456 hasConcept C521977710 @default.
• W2105863456 hasConcept C71924100 @default.
• W2105863456 hasConcept C86803240 @default.
• W2105863456 hasConceptScore W2105863456C126322002 @default.
• W2105863456 hasConceptScore W2105863456C126838900 @default.

• next