FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2105887212> ?p ?o ?g. }

• W2105887212 endingPage "3260" @default.
• W2105887212 startingPage "3260" @default.
• W2105887212 abstract "The crystal structure of a (-) gamma-lactamase from an Aureobacterium species showed a molecule bound covalently to the active site serine residue. This enzyme complex represented the first structure of a stably bound tetrahedral intermediate for an alpha/beta hydrolase fold enzyme. The structural elucidation of tetrahedral intermediates is important for the understanding of enzymatic mechanism, substrate recognition and enzyme inhibition. In this paper, we report the synthesis and subsequent characterisation of (3aR,7aS)-3a,4,7,7a-tetrahydrobenzo-[1,3]-dioxol-2-one (BD1), the molecule modelled into the Aureobacterium (-) gamma-lactamase active site. This molecule has been confirmed to be an inhibitor and to be displaced from the enzyme by the racemic gamma-lactam substrate." @default.
• W2105887212 created "2016-06-24" @default.
• W2105887212 creator A5012072623 @default.
• W2105887212 creator A5022061330 @default.
• W2105887212 creator A5032907808 @default.
• W2105887212 creator A5089726977 @default.
• W2105887212 date "2005-01-01" @default.
• W2105887212 modified "2023-10-08" @default.
• W2105887212 title "Synthesis and characterisation of a ligand that forms a stable tetrahedral intermediate in the active site of the Aureobacterium species (–)γ-lactamase" @default.
• W2105887212 cites W1531748334 @default.
• W2105887212 cites W1973468358 @default.
• W2105887212 cites W2003541451 @default.
• W2105887212 cites W2017372573 @default.
• W2105887212 cites W2028336112 @default.
• W2105887212 cites W203617234 @default.
• W2105887212 cites W2086460666 @default.
• W2105887212 cites W2092115500 @default.
• W2105887212 cites W2101956847 @default.
• W2105887212 cites W2126742511 @default.
• W2105887212 cites W2952777068 @default.
• W2105887212 doi "https://doi.org/10.1039/b511078e" @default.
• W2105887212 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16132085" @default.
• W2105887212 hasPublicationYear "2005" @default.
• W2105887212 type Work @default.
• W2105887212 sameAs 2105887212 @default.
• W2105887212 citedByCount "10" @default.
• W2105887212 countsByYear W21058872122012 @default.
• W2105887212 countsByYear W21058872122013 @default.
• W2105887212 countsByYear W21058872122014 @default.
• W2105887212 countsByYear W21058872122015 @default.
• W2105887212 countsByYear W21058872122017 @default.
• W2105887212 countsByYear W21058872122018 @default.
• W2105887212 countsByYear W21058872122019 @default.
• W2105887212 crossrefType "journal-article" @default.
• W2105887212 hasAuthorship W2105887212A5012072623 @default.
• W2105887212 hasAuthorship W2105887212A5022061330 @default.
• W2105887212 hasAuthorship W2105887212A5032907808 @default.
• W2105887212 hasAuthorship W2105887212A5089726977 @default.
• W2105887212 hasConcept C105239961 @default.
• W2105887212 hasConcept C107824862 @default.
• W2105887212 hasConcept C111368507 @default.
• W2105887212 hasConcept C115624301 @default.
• W2105887212 hasConcept C116569031 @default.
• W2105887212 hasConcept C127313418 @default.
• W2105887212 hasConcept C161790260 @default.
• W2105887212 hasConcept C170493617 @default.
• W2105887212 hasConcept C178790620 @default.
• W2105887212 hasConcept C178907741 @default.
• W2105887212 hasConcept C180577832 @default.
• W2105887212 hasConcept C181199279 @default.
• W2105887212 hasConcept C185592680 @default.
• W2105887212 hasConcept C192604958 @default.
• W2105887212 hasConcept C2776414213 @default.
• W2105887212 hasConcept C2777289219 @default.
• W2105887212 hasConcept C2780120296 @default.
• W2105887212 hasConcept C2781338088 @default.
• W2105887212 hasConcept C32909587 @default.
• W2105887212 hasConcept C41183919 @default.
• W2105887212 hasConcept C55493867 @default.
• W2105887212 hasConcept C71240020 @default.
• W2105887212 hasConcept C8010536 @default.
• W2105887212 hasConceptScore W2105887212C105239961 @default.
• W2105887212 hasConceptScore W2105887212C107824862 @default.
• W2105887212 hasConceptScore W2105887212C111368507 @default.
• W2105887212 hasConceptScore W2105887212C115624301 @default.
• W2105887212 hasConceptScore W2105887212C116569031 @default.
• W2105887212 hasConceptScore W2105887212C127313418 @default.
• W2105887212 hasConceptScore W2105887212C161790260 @default.
• W2105887212 hasConceptScore W2105887212C170493617 @default.
• W2105887212 hasConceptScore W2105887212C178790620 @default.
• W2105887212 hasConceptScore W2105887212C178907741 @default.
• W2105887212 hasConceptScore W2105887212C180577832 @default.
• W2105887212 hasConceptScore W2105887212C181199279 @default.
• W2105887212 hasConceptScore W2105887212C185592680 @default.
• W2105887212 hasConceptScore W2105887212C192604958 @default.
• W2105887212 hasConceptScore W2105887212C2776414213 @default.
• W2105887212 hasConceptScore W2105887212C2777289219 @default.
• W2105887212 hasConceptScore W2105887212C2780120296 @default.
• W2105887212 hasConceptScore W2105887212C2781338088 @default.
• W2105887212 hasConceptScore W2105887212C32909587 @default.
• W2105887212 hasConceptScore W2105887212C41183919 @default.
• W2105887212 hasConceptScore W2105887212C55493867 @default.
• W2105887212 hasConceptScore W2105887212C71240020 @default.
• W2105887212 hasConceptScore W2105887212C8010536 @default.
• W2105887212 hasIssue "18" @default.
• W2105887212 hasLocation W21058872121 @default.
• W2105887212 hasLocation W21058872122 @default.
• W2105887212 hasOpenAccess W2105887212 @default.
• W2105887212 hasPrimaryLocation W21058872121 @default.
• W2105887212 hasRelatedWork W1965076805 @default.
• W2105887212 hasRelatedWork W1988471386 @default.
• W2105887212 hasRelatedWork W2068621468 @default.
• W2105887212 hasRelatedWork W2071239653 @default.
• W2105887212 hasRelatedWork W2073351880 @default.
• W2105887212 hasRelatedWork W2086460666 @default.
• W2105887212 hasRelatedWork W2110112655 @default.
• W2105887212 hasRelatedWork W2128740036 @default.
• W2105887212 hasRelatedWork W3010944730 @default.

• next