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- W2105954911 abstract "Cytokine-induced killer cells (CIKs) have been applied in multifarious cancer. Here, we address the connection between immune therapy and clinical responses by a systematic meta-analysis. A total of 385 patients (including 183 controls) were identified for renal cell cancer (RCC) in the seven selected trials. The estimated pooled complete response and partial response showed a significant improvement for patients receiving CIK immunotherapy compared with non-CIK therapy (p < 0.0001), which was up to 62% of clinical response. The overall analysis showed a significant survival benefit (1-year overall survival [OS]: p = 0.0002; 3-year OS: p < 0.0001) in favor of CIK-based therapy in RCC, thus a statistically significant effect of OS and clinical response was demonstrated in RCC patients." @default.
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- W2105954911 date "2014-06-01" @default.
- W2105954911 modified "2023-09-30" @default.
- W2105954911 title "Cytokine-induced killer cells in the treatment of patients with renal cell carcinoma: a pooled meta-analysis" @default.
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- W2105954911 doi "https://doi.org/10.2217/imt.14.41" @default.
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