Matches in SemOpenAlex for { <https://semopenalex.org/work/W2105979763> ?p ?o ?g. }
- W2105979763 endingPage "359" @default.
- W2105979763 startingPage "349" @default.
- W2105979763 abstract "Although HIV-infected individuals harbour multiple strains of oral Candida albicans , little is known of their micro-evolution over time. Therefore, a prospective study was conducted with 16 HIV-infected ethnic Chinese individuals with and without symptoms of oropharyngeal candidiasis to evaluate the genotype distribution of oral C. albicans isolates during HIV disease progression. Oral-rinse samples were obtained from all individuals and up to five C. albicans colonies were selected for each visit, over a 12 month period of multiple visits. After identification of isolates using standard mycological criteria, the genetic similarities of yeast isolates within and between sequential clones of C. albicans were assessed by DNA fingerprinting through random amplification of polymorphic DNA (RAPD). The results of RAPD gel profiles and the lineage of each isolate were further analysed using commercially available software. RAPD studies revealed the prevalence of up to 14 different genotypes per individual during the study period, with multiple genotypes isolated simultaneously from a single oral rinse. Computer analysis of RAPD profiles revealed that yeasts isolated over sequential visits from symptomatic individuals demonstrated a striking level of relatedness compared with isolates from asymptomatic individuals. Genetically identical C. albicans strains also formed ‘loosely’ connected subclusters that overlapped multiple visits, implying genetic ‘shuffling’ in these isolates during disease progression. These data point to varying evolutionary genetic trends in C. albicans associated with symptomatic oral candidiasis and asymptomatic carriage in HIV disease." @default.
- W2105979763 created "2016-06-24" @default.
- W2105979763 creator A5001756807 @default.
- W2105979763 creator A5003019565 @default.
- W2105979763 creator A5036035572 @default.
- W2105979763 creator A5063008352 @default.
- W2105979763 creator A5063933604 @default.
- W2105979763 creator A5072300300 @default.
- W2105979763 creator A5082579429 @default.
- W2105979763 date "2003-04-01" @default.
- W2105979763 modified "2023-09-30" @default.
- W2105979763 title "`Genotypic shuffling’ of sequential clones of Candida albicans in HIV-infected individuals with and without symptomatic oral candidiasis" @default.
- W2105979763 cites W1487143634 @default.
- W2105979763 cites W1501806116 @default.
- W2105979763 cites W1508013021 @default.
- W2105979763 cites W1517805154 @default.
- W2105979763 cites W1531346399 @default.
- W2105979763 cites W1534171183 @default.
- W2105979763 cites W1536146563 @default.
- W2105979763 cites W1618514419 @default.
- W2105979763 cites W1670513352 @default.
- W2105979763 cites W1707146695 @default.
- W2105979763 cites W1789896313 @default.
- W2105979763 cites W1792359407 @default.
- W2105979763 cites W1799871145 @default.
- W2105979763 cites W1859242199 @default.
- W2105979763 cites W1911474240 @default.
- W2105979763 cites W1919939449 @default.
- W2105979763 cites W1945207787 @default.
- W2105979763 cites W1968208372 @default.
- W2105979763 cites W1973697574 @default.
- W2105979763 cites W1979513686 @default.
- W2105979763 cites W1982063085 @default.
- W2105979763 cites W2001756812 @default.
- W2105979763 cites W2009184137 @default.
- W2105979763 cites W2014775699 @default.
- W2105979763 cites W2019835459 @default.
- W2105979763 cites W2020674473 @default.
- W2105979763 cites W2026948783 @default.
- W2105979763 cites W2031686290 @default.
- W2105979763 cites W2062727898 @default.
- W2105979763 cites W2064804732 @default.
- W2105979763 cites W2093673695 @default.
- W2105979763 cites W2104181327 @default.
- W2105979763 cites W2106646481 @default.
- W2105979763 cites W2114055030 @default.
- W2105979763 cites W2117945463 @default.
- W2105979763 cites W2118488893 @default.
- W2105979763 cites W2129006376 @default.
- W2105979763 cites W2131387858 @default.
- W2105979763 cites W2135911708 @default.
- W2105979763 cites W2144715700 @default.
- W2105979763 cites W2151481540 @default.
- W2105979763 cites W2159216645 @default.
- W2105979763 cites W2161531503 @default.
- W2105979763 cites W2164822214 @default.
- W2105979763 cites W2165001863 @default.
- W2105979763 cites W2331757579 @default.
- W2105979763 cites W4211108534 @default.
- W2105979763 doi "https://doi.org/10.1099/jmm.0.04972-0" @default.
- W2105979763 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12676875" @default.
- W2105979763 hasPublicationYear "2003" @default.
- W2105979763 type Work @default.
- W2105979763 sameAs 2105979763 @default.
- W2105979763 citedByCount "40" @default.
- W2105979763 countsByYear W21059797632012 @default.
- W2105979763 countsByYear W21059797632013 @default.
- W2105979763 countsByYear W21059797632014 @default.
- W2105979763 countsByYear W21059797632016 @default.
- W2105979763 countsByYear W21059797632019 @default.
- W2105979763 crossrefType "journal-article" @default.
- W2105979763 hasAuthorship W2105979763A5001756807 @default.
- W2105979763 hasAuthorship W2105979763A5003019565 @default.
- W2105979763 hasAuthorship W2105979763A5036035572 @default.
- W2105979763 hasAuthorship W2105979763A5063008352 @default.
- W2105979763 hasAuthorship W2105979763A5063933604 @default.
- W2105979763 hasAuthorship W2105979763A5072300300 @default.
- W2105979763 hasAuthorship W2105979763A5082579429 @default.
- W2105979763 hasBestOaLocation W21059797631 @default.
- W2105979763 hasConcept C104317684 @default.
- W2105979763 hasConcept C135763542 @default.
- W2105979763 hasConcept C145081991 @default.
- W2105979763 hasConcept C159047783 @default.
- W2105979763 hasConcept C172777353 @default.
- W2105979763 hasConcept C2780917455 @default.
- W2105979763 hasConcept C2908647359 @default.
- W2105979763 hasConcept C54355233 @default.
- W2105979763 hasConcept C68873052 @default.
- W2105979763 hasConcept C71924100 @default.
- W2105979763 hasConcept C81977670 @default.
- W2105979763 hasConcept C84623179 @default.
- W2105979763 hasConcept C86803240 @default.
- W2105979763 hasConcept C89423630 @default.
- W2105979763 hasConcept C99454951 @default.
- W2105979763 hasConceptScore W2105979763C104317684 @default.
- W2105979763 hasConceptScore W2105979763C135763542 @default.
- W2105979763 hasConceptScore W2105979763C145081991 @default.
- W2105979763 hasConceptScore W2105979763C159047783 @default.