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- W2105979881 abstract "In his Commentary Levine1Levine MM Oral vaccines against cholera: lessons from Vietnam and elsewhere.Lancet. 1997; 349: 220-221Summary Full Text Full Text PDF PubMed Scopus (12) Google Scholar refers to our paper2Bastan A Evans P Milstien JB The crisis in vaccine supply.Vaccine. 1994; 12: 963-965Crossref PubMed Scopus (15) Google Scholar and states that “local production of vaccine has been proposed as a possible means of lowering costs and expediting the introduction of vaccines. The oral killed cholera vaccine locally produced in Vietnam demonstrates the feasibility of this approach”. Although production of vaccines in developing countries has the potential to assist access to new technologies, local production is not a panacea. Our assessments of several vaccine producers in developing countries indicate that quality and sustainability are a cause for concern. Governments who want to consider local production as an alternative strategy for vaccine supply should show their commitment to this route by first allocating resources to establish and maintain independent and functional national control authorities. Such authorities are needed to: continually monitor the quality of vaccines, develop a strategy for realistic production cost estimates, establish the legal and management structures to allow efficient staffing and maintenance of the manufacturing facility, and explore the product portfolio that will best meet national needs. Without this minimum commitment, local production of vaccines is not viable.3Milstien J, Batson A, Meaney W. A systematic method for evaluating the potential viability of local vaccine producers. Vaccine (in press).Google Scholar." @default.
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- W2105979881 date "1997-03-01" @default.
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- W2105979881 title "Cholera vaccines: lessons from Rwanda and elsewhere" @default.
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- W2105979881 doi "https://doi.org/10.1016/s0140-6736(05)62740-7" @default.
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