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• W2106037701 abstract "Background and Aim Several studies suggest that non‐polypoid lesions ( NPL ) show higher aggressiveness than polypoid lesions, particularly depressed lesions. The present study aimed to assess the prevalence of NPL and the presence of advanced histology in a B razilian population. Methods Two thousand and sixty‐seven superficial neoplastic lesions diagnosed in 1135 patients were analyzed. Lesions were classified as polypoid and non‐polypoid (flat and depressed) types, and evaluated for site, size, and histology (adenoma with grade of dysplasia, or early cancer). Results Prevalence of NPL was 46.5%. NPL predominated in the right colon (62.9%), whereas polypoid lesions were detected mainly in the left colon (53.2%) ( P < 0.001). NPL had a 34% higher probability of occurring in the right colon than polypoid lesions ( P < 0.001). NPL were smaller than polypoid lesions ( P = 0.03). There were 208 lesions >10 mm, of which 40 (19.2%) had advanced histology: 13% (18/138) of polypoid lesions; 27.3% (18/66) of flat lesions; and 100% (4/4) of depressed lesions ( P < 0.001). Among 1859 neoplasms ≤10 mm, only 18 (1%) had advanced histology, and 15 of them were depressed lesions ( P < 0.001). Advanced histology was more commonly detected in NPL than in polypoid lesions ( P = 0.007), with significant difference in size ( P < 0.001). NPL showed more advanced histology than polypoid lesions ( OR 2.06; P = 0.01), especially depressed lesions ( OR 36.35; P < 0.001). Among all neoplasms, the prevalence of depressed lesions was 2.2%. Conclusion NPL showed high prevalence and higher aggressiveness than polypoid lesions, especially the depressed type." @default.
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• W2106037701 date "2014-09-24" @default.
• W2106037701 modified "2023-10-17" @default.
• W2106037701 title "Prevalence of non‐polypoid colorectal neoplasms in southern <scp>B</scp>razil" @default.
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• W2106037701 doi "https://doi.org/10.1111/den.12346" @default.
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