Matches in SemOpenAlex for { <https://semopenalex.org/work/W2106062954> ?p ?o ?g. }
- W2106062954 endingPage "7290.2011.00004" @default.
- W2106062954 startingPage "7290.2011.00004" @default.
- W2106062954 abstract "Tumor-targeted fluorescence imaging for cancer diagnosis and treatment is an evolving field of research that is on the verge of clinical implementation. As each tumor has its unique biologic profile, selection of the most promising targets is essential. In this review, we focus on target finding in ovarian cancer, a disease in which fluorescence imaging may be of value in both adequate staging and in improving cytoreductive efforts, and as such may have a beneficial effect on prognosis. Thus far, tumor-targeted imaging for ovarian cancer has been applied only in animal models. For clinical implementation, the five most prominent targets were identified: folate receptor α, vascular endothelial growth factor, epidermal growth factor receptor, chemokine receptor 4, and matrix metalloproteinase. These targets were selected based on expression rates in ovarian cancer, availability of an antibody or substrate aimed at the target approved by the Food and Drug Administration, and the likelihood of translation to human use. The purpose of this review is to present requirements for intraoperative imaging and to discuss possible tumor-specific targets for ovarian cancer, prioritizing for targets with substrates ready for introduction into the clinic." @default.
- W2106062954 created "2016-06-24" @default.
- W2106062954 creator A5028689548 @default.
- W2106062954 creator A5041099300 @default.
- W2106062954 creator A5043749733 @default.
- W2106062954 creator A5059066948 @default.
- W2106062954 creator A5066146057 @default.
- W2106062954 creator A5067520596 @default.
- W2106062954 creator A5074386778 @default.
- W2106062954 creator A5077189629 @default.
- W2106062954 date "2011-07-01" @default.
- W2106062954 modified "2023-10-16" @default.
- W2106062954 title "Intraoperative Imaging in Ovarian Cancer: Fact or Fiction?" @default.
- W2106062954 cites W1493048246 @default.
- W2106062954 cites W1534824305 @default.
- W2106062954 cites W1842570318 @default.
- W2106062954 cites W1963705659 @default.
- W2106062954 cites W1963747035 @default.
- W2106062954 cites W1968521979 @default.
- W2106062954 cites W1968627984 @default.
- W2106062954 cites W1970349562 @default.
- W2106062954 cites W1974842735 @default.
- W2106062954 cites W1975148998 @default.
- W2106062954 cites W1982985645 @default.
- W2106062954 cites W1984829593 @default.
- W2106062954 cites W1985589802 @default.
- W2106062954 cites W1992819900 @default.
- W2106062954 cites W1993012864 @default.
- W2106062954 cites W1993023401 @default.
- W2106062954 cites W1993215855 @default.
- W2106062954 cites W1997841964 @default.
- W2106062954 cites W1997889852 @default.
- W2106062954 cites W1998276951 @default.
- W2106062954 cites W2000469371 @default.
- W2106062954 cites W2003868955 @default.
- W2106062954 cites W2008644522 @default.
- W2106062954 cites W2015200065 @default.
- W2106062954 cites W2015589904 @default.
- W2106062954 cites W2016068562 @default.
- W2106062954 cites W2016255001 @default.
- W2106062954 cites W2016661024 @default.
- W2106062954 cites W2016731361 @default.
- W2106062954 cites W2018797399 @default.
- W2106062954 cites W2019925311 @default.
- W2106062954 cites W2027348031 @default.
- W2106062954 cites W2030369928 @default.
- W2106062954 cites W2031744300 @default.
- W2106062954 cites W2033044209 @default.
- W2106062954 cites W2033710219 @default.
- W2106062954 cites W2037698415 @default.
- W2106062954 cites W2041801015 @default.
- W2106062954 cites W2043103956 @default.
- W2106062954 cites W2047739083 @default.
- W2106062954 cites W2047763902 @default.
- W2106062954 cites W2048939588 @default.
- W2106062954 cites W2049490668 @default.
- W2106062954 cites W2056079520 @default.
- W2106062954 cites W2059167706 @default.
- W2106062954 cites W2059614428 @default.
- W2106062954 cites W2060459188 @default.
- W2106062954 cites W2060854087 @default.
- W2106062954 cites W2061658534 @default.
- W2106062954 cites W2062051005 @default.
- W2106062954 cites W2064047613 @default.
- W2106062954 cites W2067848116 @default.
- W2106062954 cites W2070963446 @default.
- W2106062954 cites W2072347219 @default.
- W2106062954 cites W2075890715 @default.
- W2106062954 cites W2077450760 @default.
- W2106062954 cites W2080660794 @default.
- W2106062954 cites W2081995389 @default.
- W2106062954 cites W2082851035 @default.
- W2106062954 cites W2084357980 @default.
- W2106062954 cites W2091007499 @default.
- W2106062954 cites W2092238116 @default.
- W2106062954 cites W2096811763 @default.
- W2106062954 cites W2099249925 @default.
- W2106062954 cites W2100398499 @default.
- W2106062954 cites W2105651363 @default.
- W2106062954 cites W2108329606 @default.
- W2106062954 cites W2111996228 @default.
- W2106062954 cites W2116018770 @default.
- W2106062954 cites W2116818526 @default.
- W2106062954 cites W2117402284 @default.
- W2106062954 cites W2119402989 @default.
- W2106062954 cites W2122668918 @default.
- W2106062954 cites W2123894943 @default.
- W2106062954 cites W2126930429 @default.
- W2106062954 cites W2127453233 @default.
- W2106062954 cites W2134741032 @default.
- W2106062954 cites W2136071069 @default.
- W2106062954 cites W2137317814 @default.
- W2106062954 cites W2137789329 @default.
- W2106062954 cites W2139576132 @default.
- W2106062954 cites W2139932830 @default.
- W2106062954 cites W2139937771 @default.
- W2106062954 cites W2140403679 @default.
- W2106062954 cites W2140853963 @default.