FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2106151944> ?p ?o ?g. }

• W2106151944 endingPage "304" @default.
• W2106151944 startingPage "300" @default.
• W2106151944 abstract "1. Noninvasive tests for the staging of chronic hepatitis C virus (HCV) infection would be an attractive alternative to liver biopsy. The 13C-aminopyrine breath test (ABT) has been proposed for the noninvasive assessment of hepatic function and partly correlates with fibrosis. We aimed to investigate causes for the lack of discriminatory power for different degrees of hepatic fibrosis. 2. Eighty-three patients (median age 49 years (28-78 years)) with chronic HCV infection underwent the ABT after an oral load of 75 mg N,N-dimethyl-13C-aminopyrine. Portal vein flow was assessed by duplex-Doppler and a laboratory index (aspartate aminotransferase to platelet ratio index or APRI) was calculated. Parameters were compared with liver histology. 3. The cumulative 13C-recovery differed significantly between patients without relevant fibrosis (fibrosis score 0-2) and cirrhosis (5-6), beginning after 30 min of sampling (P < 0.05). The ABT did not discriminate patients with fibrosis scores 3-4 from the remaining two patient groups. Sensitivity and specificity for the prediction of cirrhosis was 73.4-82.8% and 63.2-68.4%, depending on the sampling time. Compared with the fibrosis score (P = 0.04), patient age was a highly significant independent predictor for the 13C-recovery (P < 0.0001). Aspartate aminotransferase to platelet ratio index and duplex-Doppler predicted cirrhosis with 76.6%vs. 87.5% sensitivity and 63.2%vs. 68.4% specificity. 4. Our data suggest an age-dependent decrease of cytochrome P450 activity which probably accounts for the large overlap of ABT results that preclude clear differentiation. This is also consistent with former pharmacodynamic trials. Age-adapted reference ranges could improve ABT results." @default.
• W2106151944 created "2016-06-24" @default.
• W2106151944 creator A5003336645 @default.
• W2106151944 creator A5010474616 @default.
• W2106151944 creator A5020343474 @default.
• W2106151944 creator A5026804105 @default.
• W2106151944 creator A5039181755 @default.
• W2106151944 creator A5078231949 @default.
• W2106151944 creator A5080054296 @default.
• W2106151944 date "2006-03-16" @default.
• W2106151944 modified "2023-10-10" @default.
• W2106151944 title "PATIENT AGE IS A STRONG INDEPENDENT PREDICTOR OF 13C-AMINOPYRINE BREATH TEST RESULTS: A COMPARATIVE STUDY WITH HISTOLOGY, DUPLEX-DOPPLER AND A LABORATORY INDEX IN PATIENTS WITH CHRONIC HEPATITIS C VIRUS INFECTION" @default.
• W2106151944 cites W170189751 @default.
• W2106151944 cites W1964561230 @default.
• W2106151944 cites W1966050415 @default.
• W2106151944 cites W1966467761 @default.
• W2106151944 cites W1981900811 @default.
• W2106151944 cites W1982443836 @default.
• W2106151944 cites W1982908754 @default.
• W2106151944 cites W1987881030 @default.
• W2106151944 cites W1995813950 @default.
• W2106151944 cites W1997865776 @default.
• W2106151944 cites W2000524760 @default.
• W2106151944 cites W2002693341 @default.
• W2106151944 cites W2017515989 @default.
• W2106151944 cites W2018979713 @default.
• W2106151944 cites W2025400870 @default.
• W2106151944 cites W2027498662 @default.
• W2106151944 cites W2034013430 @default.
• W2106151944 cites W2036536337 @default.
• W2106151944 cites W2044245630 @default.
• W2106151944 cites W2049974839 @default.
• W2106151944 cites W2084430452 @default.
• W2106151944 cites W2086889982 @default.
• W2106151944 cites W2087829753 @default.
• W2106151944 cites W2088740988 @default.
• W2106151944 cites W2116153849 @default.
• W2106151944 cites W2116874804 @default.
• W2106151944 cites W2118036010 @default.
• W2106151944 cites W2127557833 @default.
• W2106151944 cites W2330461642 @default.
• W2106151944 cites W2765799726 @default.
• W2106151944 doi "https://doi.org/10.1111/j.1440-1681.2006.04365.x" @default.
• W2106151944 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16620291" @default.
• W2106151944 hasPublicationYear "2006" @default.
• W2106151944 type Work @default.
• W2106151944 sameAs 2106151944 @default.
• W2106151944 citedByCount "20" @default.
• W2106151944 countsByYear W21061519442012 @default.
• W2106151944 countsByYear W21061519442013 @default.
• W2106151944 countsByYear W21061519442014 @default.
• W2106151944 countsByYear W21061519442015 @default.
• W2106151944 countsByYear W21061519442017 @default.
• W2106151944 crossrefType "journal-article" @default.
• W2106151944 hasAuthorship W2106151944A5003336645 @default.
• W2106151944 hasAuthorship W2106151944A5010474616 @default.
• W2106151944 hasAuthorship W2106151944A5020343474 @default.
• W2106151944 hasAuthorship W2106151944A5026804105 @default.
• W2106151944 hasAuthorship W2106151944A5039181755 @default.
• W2106151944 hasAuthorship W2106151944A5078231949 @default.
• W2106151944 hasAuthorship W2106151944A5080054296 @default.
• W2106151944 hasConcept C126322002 @default.
• W2106151944 hasConcept C203014093 @default.
• W2106151944 hasConcept C2522874641 @default.
• W2106151944 hasConcept C2775934546 @default.
• W2106151944 hasConcept C2775981797 @default.
• W2106151944 hasConcept C2776408679 @default.
• W2106151944 hasConcept C2776409635 @default.
• W2106151944 hasConcept C2777214474 @default.
• W2106151944 hasConcept C2777513400 @default.
• W2106151944 hasConcept C2777766500 @default.
• W2106151944 hasConcept C2780040827 @default.
• W2106151944 hasConcept C2780559512 @default.
• W2106151944 hasConcept C512861765 @default.
• W2106151944 hasConcept C71924100 @default.
• W2106151944 hasConcept C90924648 @default.
• W2106151944 hasConceptScore W2106151944C126322002 @default.
• W2106151944 hasConceptScore W2106151944C203014093 @default.
• W2106151944 hasConceptScore W2106151944C2522874641 @default.
• W2106151944 hasConceptScore W2106151944C2775934546 @default.
• W2106151944 hasConceptScore W2106151944C2775981797 @default.
• W2106151944 hasConceptScore W2106151944C2776408679 @default.
• W2106151944 hasConceptScore W2106151944C2776409635 @default.
• W2106151944 hasConceptScore W2106151944C2777214474 @default.
• W2106151944 hasConceptScore W2106151944C2777513400 @default.
• W2106151944 hasConceptScore W2106151944C2777766500 @default.
• W2106151944 hasConceptScore W2106151944C2780040827 @default.
• W2106151944 hasConceptScore W2106151944C2780559512 @default.
• W2106151944 hasConceptScore W2106151944C512861765 @default.
• W2106151944 hasConceptScore W2106151944C71924100 @default.
• W2106151944 hasConceptScore W2106151944C90924648 @default.
• W2106151944 hasIssue "4" @default.
• W2106151944 hasLocation W21061519441 @default.
• W2106151944 hasLocation W21061519442 @default.
• W2106151944 hasOpenAccess W2106151944 @default.
• W2106151944 hasPrimaryLocation W21061519441 @default.
• W2106151944 hasRelatedWork W1553503019 @default.
• W2106151944 hasRelatedWork W188112378 @default.

• next