FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2106196303> ?p ?o ?g. }

• W2106196303 endingPage "2108" @default.
• W2106196303 startingPage "2103" @default.
• W2106196303 abstract "Interferon (IFN)-gamma, a key immunoregulatory cytokine, has been thought to be produced solely by activated T cells and natural killer cells. In this study, we show that murine bone marrow- derived macrophages (BMMPhi) secrete large amounts of IFN-gamma upon appropriate stimulation. Although interleukin (IL)-12 and IL-18 alone induce low levels of IFN-gamma mRNA transcripts, the combined stimulation of BMMPhi with both cytokines leads to the efficient production of IFN-gamma protein. The macrophage-derived IFN-gamma is biologically active as shown by induction of inducible nitric oxide synthase as well as upregulation of CD40 in macrophages. Our findings uncover a novel pathway of autocrine macrophage activation by demonstrating that the macrophage is not only a key cell type responding to IFN-gamma but also a potent IFN-gamma-producing cell." @default.
• W2106196303 created "2016-06-24" @default.
• W2106196303 creator A5009040158 @default.
• W2106196303 creator A5016153688 @default.
• W2106196303 creator A5041374198 @default.
• W2106196303 creator A5073623750 @default.
• W2106196303 date "1998-06-15" @default.
• W2106196303 modified "2023-10-10" @default.
• W2106196303 title "Murine Macrophages Secrete Interferon γ upon Combined Stimulation with Interleukin (IL)-12 and IL-18: A Novel Pathway of Autocrine Macrophage Activation" @default.
• W2106196303 cites W1579094233 @default.
• W2106196303 cites W1905805852 @default.
• W2106196303 cites W1964323924 @default.
• W2106196303 cites W1984188855 @default.
• W2106196303 cites W1988820544 @default.
• W2106196303 cites W1991137313 @default.
• W2106196303 cites W2022049443 @default.
• W2106196303 cites W2023803780 @default.
• W2106196303 cites W2068871282 @default.
• W2106196303 cites W2069967614 @default.
• W2106196303 cites W2108473659 @default.
• W2106196303 cites W2124576546 @default.
• W2106196303 cites W2134768631 @default.
• W2106196303 cites W2134812217 @default.
• W2106196303 cites W2143576308 @default.
• W2106196303 cites W2149200346 @default.
• W2106196303 cites W2151925533 @default.
• W2106196303 cites W2152420574 @default.
• W2106196303 cites W2167922967 @default.
• W2106196303 cites W2171831396 @default.
• W2106196303 cites W4294216491 @default.
• W2106196303 doi "https://doi.org/10.1084/jem.187.12.2103" @default.
• W2106196303 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2212367" @default.
• W2106196303 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9625771" @default.
• W2106196303 hasPublicationYear "1998" @default.
• W2106196303 type Work @default.
• W2106196303 sameAs 2106196303 @default.
• W2106196303 citedByCount "580" @default.
• W2106196303 countsByYear W21061963032012 @default.
• W2106196303 countsByYear W21061963032013 @default.
• W2106196303 countsByYear W21061963032014 @default.
• W2106196303 countsByYear W21061963032015 @default.
• W2106196303 countsByYear W21061963032016 @default.
• W2106196303 countsByYear W21061963032017 @default.
• W2106196303 countsByYear W21061963032018 @default.
• W2106196303 countsByYear W21061963032019 @default.
• W2106196303 countsByYear W21061963032020 @default.
• W2106196303 countsByYear W21061963032021 @default.
• W2106196303 countsByYear W21061963032022 @default.
• W2106196303 countsByYear W21061963032023 @default.
• W2106196303 crossrefType "journal-article" @default.
• W2106196303 hasAuthorship W2106196303A5009040158 @default.
• W2106196303 hasAuthorship W2106196303A5016153688 @default.
• W2106196303 hasAuthorship W2106196303A5041374198 @default.
• W2106196303 hasAuthorship W2106196303A5073623750 @default.
• W2106196303 hasBestOaLocation W21061963031 @default.
• W2106196303 hasConcept C128240485 @default.
• W2106196303 hasConcept C134018914 @default.
• W2106196303 hasConcept C202751555 @default.
• W2106196303 hasConcept C203014093 @default.
• W2106196303 hasConcept C24998067 @default.
• W2106196303 hasConcept C2776178377 @default.
• W2106196303 hasConcept C2778690821 @default.
• W2106196303 hasConcept C2779244956 @default.
• W2106196303 hasConcept C2780841837 @default.
• W2106196303 hasConcept C49039625 @default.
• W2106196303 hasConcept C519581460 @default.
• W2106196303 hasConcept C54355233 @default.
• W2106196303 hasConcept C55493867 @default.
• W2106196303 hasConcept C81885089 @default.
• W2106196303 hasConcept C86803240 @default.
• W2106196303 hasConcept C95444343 @default.
• W2106196303 hasConceptScore W2106196303C128240485 @default.
• W2106196303 hasConceptScore W2106196303C134018914 @default.
• W2106196303 hasConceptScore W2106196303C202751555 @default.
• W2106196303 hasConceptScore W2106196303C203014093 @default.
• W2106196303 hasConceptScore W2106196303C24998067 @default.
• W2106196303 hasConceptScore W2106196303C2776178377 @default.
• W2106196303 hasConceptScore W2106196303C2778690821 @default.
• W2106196303 hasConceptScore W2106196303C2779244956 @default.
• W2106196303 hasConceptScore W2106196303C2780841837 @default.
• W2106196303 hasConceptScore W2106196303C49039625 @default.
• W2106196303 hasConceptScore W2106196303C519581460 @default.
• W2106196303 hasConceptScore W2106196303C54355233 @default.
• W2106196303 hasConceptScore W2106196303C55493867 @default.
• W2106196303 hasConceptScore W2106196303C81885089 @default.
• W2106196303 hasConceptScore W2106196303C86803240 @default.
• W2106196303 hasConceptScore W2106196303C95444343 @default.
• W2106196303 hasIssue "12" @default.
• W2106196303 hasLocation W21061963031 @default.
• W2106196303 hasLocation W21061963032 @default.
• W2106196303 hasLocation W21061963033 @default.
• W2106196303 hasLocation W21061963034 @default.
• W2106196303 hasOpenAccess W2106196303 @default.
• W2106196303 hasPrimaryLocation W21061963031 @default.
• W2106196303 hasRelatedWork W1969354036 @default.
• W2106196303 hasRelatedWork W2036970031 @default.
• W2106196303 hasRelatedWork W2042234954 @default.
• W2106196303 hasRelatedWork W2059685024 @default.

• next