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- W2106202344 abstract "<h3>BACKGROUND AND PURPOSE:</h3> PCMR, widely used for the evaluation of blood flow, has been adopted for the assessment of cerebrospinal fluid flow in a variety of disorders. The purpose of this study was to evaluate the accuracy and reproducibility of 2 fast PCMR techniques for measuring CSF flow. <h3>MATERIALS AND METHODS:</h3> Velocities were calculated from RPC and CPC images of fluid flowing in a tube at a constant velocity. Error and the COV were computed for average and peak velocities. Additionally, measurements of sinusoidally fluctuating flow and of CSF flow in 5 healthy volunteers were acquired with the RPC and CPC acquisitions. <h3>RESULTS:</h3> For constant velocity experiments, error for the RPC and CPC acquisitions averaged +1.15% and +8.91% and COVs averaged 1.29% and 3.01%, respectively. For peak velocities of ≥12.6 cm/s, error with RPC or CPC ranged from −33.3% to −36.9% and COVs were 0%–4% for RPC and 1%–7% for CPC. For peak velocities of ≤6.4 cm/s, RPC and CPC overestimated velocity by >250%. For fluctuating flow, both acquisitions showed similar flow patterns. In volunteer studies, peak systolic and diastolic velocities were not significantly different. <h3>CONCLUSIONS:</h3> The RPC and CPC sequences measure velocities on the order of CSF flow with an average error of ≥9%. The 2 techniques significantly overestimate peak velocities <6.4 cm/s, with maximum errors of 209% and 276% and maximum COVs of 100% and 73% for the RPC and CPC sequences, respectively. Measurements of CSF velocities in human volunteers and of sinusoidally fluctuating phantom velocities did not differ significantly between the 2 techniques." @default.
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- W2106202344 date "2009-03-01" @default.
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- W2106202344 title "Transgenerational inheritance of environmental obesogens" @default.
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- W2106202344 doi "https://doi.org/10.1136/oem.2008.043307" @default.
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