FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2106215183> ?p ?o ?g. }

• W2106215183 endingPage "2224" @default.
• W2106215183 startingPage "2213" @default.
• W2106215183 abstract "Amid the explosion of fundamental knowledge generated from transgenic animal models, a small group of scientists has been producing transgenic livestock with goals of improving animal production efficiency and generating new products. The ability to modify mammary-specific genes provides an opportunity to pursue several distinctly different avenues of research. The objective of the emerging gene pharming industry is to produce pharmaceuticals for treating human diseases. It is argued that mammary glands are an ideal site for producing complex bioactive proteins that can be cost effectively harvested and purified. Consequently, during the past decade, approximately a dozen companies have been created to capture the US market for pharmaceuticals produced from transgenic bioreactors estimated at $3 billion annually. Several products produced in this way are now in human clinical trials. Another research direction, which has been widely discussed but has received less attention in the laboratory, is genetic engineering of the bovine mammary gland to alter the composition of milk destined for human consumption. Proposals include increasing or altering endogenous proteins, decreasing fat, and altering milk composition to resemble that of human milk. Initial studies using transgenic mice to investigate the feasibility of enhancing manufacturing properties of milk have been encouraging. The potential profitability of gene pharming seems clear, as do the benefits of transgenic cows producing milk that has been optimized for food products. To take full advantage of enhanced milk, it may be desirable to restructure the method by which dairy producers are compensated. However, the cost of producing functional transgenic cattle will remain a severe limitation to realizing the potential of transgenic cattle until inefficiencies of transgenic technology are overcome. These inefficiencies include low rates of gene integration, poor embryo survival, and unpredictable transgene behavior." @default.
• W2106215183 created "2016-06-24" @default.
• W2106215183 creator A5021969645 @default.
• W2106215183 creator A5028397274 @default.
• W2106215183 creator A5068281338 @default.
• W2106215183 date "1997-09-01" @default.
• W2106215183 modified "2023-10-14" @default.
• W2106215183 title "Transgenic Dairy Cattle: Genetic Engineering on a Large Scale" @default.
• W2106215183 cites W1249413574 @default.
• W2106215183 cites W1522330173 @default.
• W2106215183 cites W1671211416 @default.
• W2106215183 cites W1918549573 @default.
• W2106215183 cites W1963524555 @default.
• W2106215183 cites W1964311222 @default.
• W2106215183 cites W1965937576 @default.
• W2106215183 cites W1968283357 @default.
• W2106215183 cites W1968444257 @default.
• W2106215183 cites W1968458490 @default.
• W2106215183 cites W1979111113 @default.
• W2106215183 cites W1984124191 @default.
• W2106215183 cites W1991298002 @default.
• W2106215183 cites W1991758422 @default.
• W2106215183 cites W1994435996 @default.
• W2106215183 cites W1994796442 @default.
• W2106215183 cites W2000894587 @default.
• W2106215183 cites W2001062265 @default.
• W2106215183 cites W2004595716 @default.
• W2106215183 cites W2005374266 @default.
• W2106215183 cites W2021598200 @default.
• W2106215183 cites W2022677304 @default.
• W2106215183 cites W2024920454 @default.
• W2106215183 cites W2026364069 @default.
• W2106215183 cites W2033163944 @default.
• W2106215183 cites W2034690498 @default.
• W2106215183 cites W2035670990 @default.
• W2106215183 cites W2036091357 @default.
• W2106215183 cites W2036510455 @default.
• W2106215183 cites W2039690063 @default.
• W2106215183 cites W2040415371 @default.
• W2106215183 cites W2041782104 @default.
• W2106215183 cites W2043381873 @default.
• W2106215183 cites W2044613450 @default.
• W2106215183 cites W2049858733 @default.
• W2106215183 cites W2052575270 @default.
• W2106215183 cites W2060602978 @default.
• W2106215183 cites W2065983616 @default.
• W2106215183 cites W2068044379 @default.
• W2106215183 cites W2070416150 @default.
• W2106215183 cites W2074565496 @default.
• W2106215183 cites W2074611792 @default.
• W2106215183 cites W2081419743 @default.
• W2106215183 cites W2084773650 @default.
• W2106215183 cites W2086264824 @default.
• W2106215183 cites W2088135095 @default.
• W2106215183 cites W2092720597 @default.
• W2106215183 cites W2097958363 @default.
• W2106215183 cites W2098919318 @default.
• W2106215183 cites W2101311932 @default.
• W2106215183 cites W2114339139 @default.
• W2106215183 cites W2118299921 @default.
• W2106215183 cites W2122538846 @default.
• W2106215183 cites W2140338297 @default.
• W2106215183 cites W2146948025 @default.
• W2106215183 cites W2148598734 @default.
• W2106215183 cites W2151012377 @default.
• W2106215183 cites W2155747503 @default.
• W2106215183 cites W2167002098 @default.
• W2106215183 cites W2169318769 @default.
• W2106215183 cites W2171457459 @default.
• W2106215183 cites W2171892478 @default.
• W2106215183 cites W2401884707 @default.
• W2106215183 cites W2405762537 @default.
• W2106215183 cites W2769705160 @default.
• W2106215183 doi "https://doi.org/10.3168/jds.s0022-0302(97)76170-8" @default.
• W2106215183 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9313167" @default.
• W2106215183 hasPublicationYear "1997" @default.
• W2106215183 type Work @default.
• W2106215183 sameAs 2106215183 @default.
• W2106215183 citedByCount "142" @default.
• W2106215183 countsByYear W21062151832012 @default.
• W2106215183 countsByYear W21062151832013 @default.
• W2106215183 countsByYear W21062151832014 @default.
• W2106215183 countsByYear W21062151832015 @default.
• W2106215183 countsByYear W21062151832016 @default.
• W2106215183 countsByYear W21062151832017 @default.
• W2106215183 countsByYear W21062151832018 @default.
• W2106215183 countsByYear W21062151832020 @default.
• W2106215183 countsByYear W21062151832021 @default.
• W2106215183 countsByYear W21062151832022 @default.
• W2106215183 countsByYear W21062151832023 @default.
• W2106215183 crossrefType "journal-article" @default.
• W2106215183 hasAuthorship W2106215183A5021969645 @default.
• W2106215183 hasAuthorship W2106215183A5028397274 @default.
• W2106215183 hasAuthorship W2106215183A5068281338 @default.
• W2106215183 hasBestOaLocation W21062151831 @default.
• W2106215183 hasConcept C10138342 @default.
• W2106215183 hasConcept C102230213 @default.
• W2106215183 hasConcept C104317684 @default.

• next