FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2106233388> ?p ?o ?g. }

• W2106233388 endingPage "37" @default.
• W2106233388 startingPage "27" @default.
• W2106233388 abstract "“Bendectin”1 Bendectin is the US trademark for a combination of doxylamine and dicyclomine used for the treatment of nausea and vomiting of pregnancy. Prior to 1977, it also contained pyridoxine. Analogous products were distributed in the United Kingdom under the trademark “Debendox” and in Germany under the trademark “Lenotan.” (Doxylamine/Dicyclomine/Pyridoxine) was widely used for the treatment of nausea and vomiting of pregnancy until 1983, when production was discontinued in the face of lawsuits alleging that the drug caused congenital malformations. We have conducted a meta-analysis of the 16 cohort and 11 case-control studies that report birth defects from Bendectin-exposed pregnancies. This meta-analysis provides an estimate of the relative risk of malformation at birth in association with Bendectin exposure. The pooled estimate of the relative risk of any malformation at birth in association with exposure to Bendectin in the first trimester was 0. 95 (95% Cl 0. 88 to 1. 04). Separate analyses were undertaken for cardiac defects, central nervous system defects, neural tube defects, limb reductions, oral clefts, and genital tract malformations. In these categories, the pooled estimates of relative risk ranged from 0. 81 for oral clefts to 1. 11 for limb reductions, with all 95% confidence intervals enclosing unity. With the exception of studies for oral clefts and for pyloristenosis, tests for heterogeneity of association indicated for each table that all studies were estimating the same odds ratio. These studies, as a group, showed no difference in the risk of birth defects between those infants whose mothers had taken Bendectin during the first trimester of pregnancy and those infants whose mothers had not. It is unlikely that Bendectin exposure contributed to the prevalence of congenital malformations in the population.© 1994 Wiley-Liss, Inc." @default.
• W2106233388 created "2016-06-24" @default.
• W2106233388 creator A5039750697 @default.
• W2106233388 creator A5045092409 @default.
• W2106233388 creator A5068113049 @default.
• W2106233388 creator A5075394996 @default.
• W2106233388 date "1994-07-01" @default.
• W2106233388 modified "2023-09-26" @default.
• W2106233388 title "Bendectin and birth defects: I. A meta-analysis of the epidemiologic studies" @default.
• W2106233388 cites W114494166 @default.
• W2106233388 cites W124264984 @default.
• W2106233388 cites W1496824121 @default.
• W2106233388 cites W153146129 @default.
• W2106233388 cites W1533051529 @default.
• W2106233388 cites W1838960985 @default.
• W2106233388 cites W1893986155 @default.
• W2106233388 cites W1964387971 @default.
• W2106233388 cites W1968411380 @default.
• W2106233388 cites W1972427998 @default.
• W2106233388 cites W1972901922 @default.
• W2106233388 cites W1974546287 @default.
• W2106233388 cites W1983182797 @default.
• W2106233388 cites W2019336047 @default.
• W2106233388 cites W2023232505 @default.
• W2106233388 cites W2030269002 @default.
• W2106233388 cites W2042732005 @default.
• W2106233388 cites W2043406379 @default.
• W2106233388 cites W2046323669 @default.
• W2106233388 cites W2067151668 @default.
• W2106233388 cites W2082648614 @default.
• W2106233388 cites W2094620730 @default.
• W2106233388 cites W2102704463 @default.
• W2106233388 cites W2164071690 @default.
• W2106233388 cites W2268856865 @default.
• W2106233388 cites W2272466511 @default.
• W2106233388 cites W2400187501 @default.
• W2106233388 cites W2405117596 @default.
• W2106233388 cites W4238379213 @default.
• W2106233388 cites W4293874313 @default.
• W2106233388 doi "https://doi.org/10.1002/tera.1420500105" @default.
• W2106233388 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7974252" @default.
• W2106233388 hasPublicationYear "1994" @default.
• W2106233388 type Work @default.
• W2106233388 sameAs 2106233388 @default.
• W2106233388 citedByCount "170" @default.
• W2106233388 countsByYear W21062333882012 @default.
• W2106233388 countsByYear W21062333882013 @default.
• W2106233388 countsByYear W21062333882014 @default.
• W2106233388 countsByYear W21062333882015 @default.
• W2106233388 countsByYear W21062333882016 @default.
• W2106233388 countsByYear W21062333882017 @default.
• W2106233388 countsByYear W21062333882018 @default.
• W2106233388 countsByYear W21062333882019 @default.
• W2106233388 countsByYear W21062333882021 @default.
• W2106233388 countsByYear W21062333882022 @default.
• W2106233388 crossrefType "journal-article" @default.
• W2106233388 hasAuthorship W2106233388A5039750697 @default.
• W2106233388 hasAuthorship W2106233388A5045092409 @default.
• W2106233388 hasAuthorship W2106233388A5068113049 @default.
• W2106233388 hasAuthorship W2106233388A5075394996 @default.
• W2106233388 hasConcept C126322002 @default.
• W2106233388 hasConcept C131872663 @default.
• W2106233388 hasConcept C141071460 @default.
• W2106233388 hasConcept C156957248 @default.
• W2106233388 hasConcept C187212893 @default.
• W2106233388 hasConcept C2779234561 @default.
• W2106233388 hasConcept C2780580376 @default.
• W2106233388 hasConcept C2780852908 @default.
• W2106233388 hasConcept C44249647 @default.
• W2106233388 hasConcept C46973012 @default.
• W2106233388 hasConcept C54355233 @default.
• W2106233388 hasConcept C65290608 @default.
• W2106233388 hasConcept C71924100 @default.
• W2106233388 hasConcept C82789193 @default.
• W2106233388 hasConcept C86803240 @default.
• W2106233388 hasConceptScore W2106233388C126322002 @default.
• W2106233388 hasConceptScore W2106233388C131872663 @default.
• W2106233388 hasConceptScore W2106233388C141071460 @default.
• W2106233388 hasConceptScore W2106233388C156957248 @default.
• W2106233388 hasConceptScore W2106233388C187212893 @default.
• W2106233388 hasConceptScore W2106233388C2779234561 @default.
• W2106233388 hasConceptScore W2106233388C2780580376 @default.
• W2106233388 hasConceptScore W2106233388C2780852908 @default.
• W2106233388 hasConceptScore W2106233388C44249647 @default.
• W2106233388 hasConceptScore W2106233388C46973012 @default.
• W2106233388 hasConceptScore W2106233388C54355233 @default.
• W2106233388 hasConceptScore W2106233388C65290608 @default.
• W2106233388 hasConceptScore W2106233388C71924100 @default.
• W2106233388 hasConceptScore W2106233388C82789193 @default.
• W2106233388 hasConceptScore W2106233388C86803240 @default.
• W2106233388 hasIssue "1" @default.
• W2106233388 hasLocation W21062333881 @default.
• W2106233388 hasLocation W21062333882 @default.
• W2106233388 hasOpenAccess W2106233388 @default.
• W2106233388 hasPrimaryLocation W21062333881 @default.
• W2106233388 hasRelatedWork W1526443923 @default.
• W2106233388 hasRelatedWork W2015128831 @default.
• W2106233388 hasRelatedWork W2019294467 @default.

• next