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- W2106237215 abstract "Letters5 August 2003Health Care–Associated Bloodstream InfectionsKeith S. Kaye, MD, MPH, N. Deborah Friedman, MBBS, and Daniel J. Sexton, MDKeith S. Kaye, MD, MPHDuke University Medical Center; Durham, NC 27710 (Kaye, Friedman, Sexton)Search for more papers by this author, N. Deborah Friedman, MBBSDuke University Medical Center; Durham, NC 27710 (Kaye, Friedman, Sexton)Search for more papers by this author, and Daniel J. Sexton, MDDuke University Medical Center; Durham, NC 27710 (Kaye, Friedman, Sexton)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-139-3-200308050-00018 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:The primary objective of our study was to develop a new classification scheme for bloodstream infection that distinguishes among community-acquired and health care–associated bloodstream infections. Dr. Zetola states that subgroups within the health care–associated category we proposed have not been proven to be associated with infection caused by antimicrobial-resistant bacteria and that use of unnecessary broad-spectrum antibiotics might harm patients by leading to resistance. The most significant antimicrobial-resistant pathogen isolated in our study was methicillin-resistant S. aureus (MRSA). This was the infecting pathogen in 19% of patients with health care–associated bacteremia and 20% of patients with nosocomial bacteremia ...References1. Morin CA, Hadler JL. Population-based incidence and characteristics of community-onset Staphylococcus aureus infections with bacteremia in 4 metropolitan Connecticut areas, 1998. J Infect Dis. 2001;184:1029-34. [PMID: 11574918] CrossrefMedlineGoogle Scholar2. Steinberg JP, Clark CC, Hackman BO. Nosocomial and community-acquired Staphylococcus aureus bacteremias from 1980 to 1993: impact of intravascular devices and methicillin resistance. Clin Infect Dis. 1996;23:255-9. [PMID: 8842259] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Duke University Medical Center; Durham, NC 27710 (Kaye, Friedman, Sexton) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoHealth Care–Associated Bloodstream Infections in Adults: A Reason To Change the Accepted Definition of Community-Acquired Infections N. Deborah Friedman , Keith S. Kaye , Jason E. Stout , Sarah A. McGarry , Sharon L. Trivette , Jane P. Briggs , Wanda Lamm , Connie Clark , Jennifer MacFarquhar , Aaron L. Walton , L. Barth Reller , and Daniel J. Sexton Health Care–Associated Bloodstream Infections Nicola M. Zetola Metrics Cited ByWas endothermy in amniotes induced by an early stop in growth during ontogeny?Role of leptin in energy expenditure: the hypothalamic perspectiveThe relation between changes in thyroid function and anthropometric indices during long-term follow-up of euthyroid subjects: the Tehran Thyroid Study (TTS)Free Thyroxine and Functional Mobility, Fitness, and Fatigue in Euthyroid Older Men and Women in the Baltimore Longitudinal Study of AgingEndocrine Disorders Associated with ObesityAssociation between thyroid hormones, thyroid antibodies and insulin resistance in euthyroid individuals: A population-based cohortThyroid hormone status affects expression of daily torpor and gene transcription in Djungarian hamsters (Phodopus sungorus)Median-lower normal levels of serum thyroxine are associated with low triiodothyronine levels and body temperature in patients with central hypothyroidismCoping with change: A framework for environmental signals and how neuroendocrine pathways might respondProstaglandin E synthase interacts with inducible heat shock protein 70 after heat stress in bovine primary dermal fibroblast cellsEndocrine Disorders Associated with ObesityPharmaceutical Studies of Levothyroxine Sodium Hydrate Suppository Provided as a Hospital PreparationSerum Concentrations of Ghrelin and Leptin according to Thyroid Hormone Condition, and Their Correlations with Insulin ResistanceA Case of Massive Levothyroxine Intoxication in a Patient with Total ThyroidectomyThermogenesis and longevity in mammals. Thyroxin model of accelerated agingEmerging Regulation and Function of BetatrophinTemporary forced oral breathing affects neonates oxygen consumption, carbon dioxide elimination, diaphragm muscles structure and physiological parametersHypothalamic effects of thyroid hormones on metabolismMECHANISMS IN ENDOCRINOLOGY: The crosstalk between thyroid gland and adipose tissue: signal integration in health and diseaseSeasonal Variation of Metabolic Thermogenesis in Eurasian Tree Sparrows ( Passer montanus ) over a Latitudinal GradientBody temperature and thermal environment in a generalized arboreal anthropoid, wild mantled howling monkeys ( Alouatta palliata )Association between Lower Normal Free Thyroxine Concentrations and Obesity Phenotype in Healthy Euthyroid SubjectsPrevalence and Risk Factors of Subclinical Thyroid DiseaseThe Significance of Alteration 2-[fluorine-18]fluoro-2-deoxy-d-glucose Uptake in the Liver and Skeletal Muscles of Patients with HyperthyroidismInappropriate heat dissipation ignites brown fat thermogenesis in mice with a mutant thyroid hormone receptor 1TSH and free triiodothyronine concentrations are associated with weight loss in a lifestyle intervention and weight regain afterwards in obese childrenHypothyroidism in the Adult Rat Causes Incremental Changes in Brain-Derived Neurotrophic Factor, Neuronal and Astrocyte Apoptosis, Gliosis, and Deterioration of Postsynaptic DensityMethods for Studying the Ecological Physiology of Feeding in Free-Ranging Howlers (Alouatta palliata) at La Pacifica, Costa RicaHuman EnergeticsAssociation of Metabolic Syndrome Parameters with TT3 and FT3/FT4 Ratio in Obese Turkish PopulationRole of the hypothalamus in the neuroendocrine regulation of body weight and composition during energy deficitAssociation Analyses of Variants in the DIO2 Gene with Early-Onset Type 2 Diabetes Mellitus in Pima IndiansMale Child with Van Wyk-Grumbach's Syndrome and Other Complications of Long-Standing Primary Hypothyroidism: A Case ReportEffects of short term forced oral breathing: Physiological changes and structural adaptation of diaphragm and orofacial muscles in ratsCentral neuropeptide Y infusion and melanocortin 4 receptor antagonism inhibit thyrotropic function by divergent pathwaysBrown adipose tissue in the treatment of obesity and diabetes: Are we hot enough?Embryonic control of heart rate: Examining developmental patterns and temperature and oxygenation influences using embryonic avian modelsThyroid hormone action on skinDirect effects of iodothyronines on excess fat storage in rat hepatocytesTreatment of paediatric hyperthyroidism but not hypothyroidism has a significant effect on weightNon-invasive measurement of thyroid hormone in feces of a diverse array of avian and mammalian speciesA high normal TSH is associated with the metabolic syndromeThyroid and Adrenal DisordersFree thyroxine is an independent predictor of subcutaneous fat in euthyroid individualsFunctional expression of the thyrotropin receptor in C cells: new insights into their involvement in the hypothalamic-pituitary-thyroid axisEndocrine and metabolic effects of smoking cessationPlasma total and acylated Ghrelin concentrations in patients with clinical and subclinical thyroid dysfunctionThyroid hormones and multiple organ dysfunction syndromeThe effect of heat stress on thyroid hormone response and meat quality in turkeys of two genetic linesThe influence of basal metabolic rate on blood pressure among indigenous SiberiansSerum Leptin and Ghrelin Levels in Premenopausal Women with Stable Body Mass Index during Treatment of Thyroid DysfunctionEffect of Levo-Thyroxine Treatment on Weight and Body Mass Index in Children with Acquired HypothyroidismNonequilibrium thermodynamics and energy efficiency in weight loss dietsInfluence of thyroid dysfunction on serum concentrations of adipocytokinesTargeting thyroid hormone receptor-beta agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic indexThermogenic and metabolic antiobesity drugs: rationale and opportunitiesThyrotrophin-Releasing Hormone Decreases Feeding and Increases Body Temperature, Activity and Oxygen Consumption in Siberian HamstersThermoregulationFoetal adaptation at birthFetal adaptation at birthNeuroendocrine implications for the association between cocaine- and amphetamine regulated transcript (CART) and hypophysiotropic thyrotropin-releasing hormone (TRH)Thyroid hormones increase liver and muscle thermogenic capacity in the little buntings (Emberiza pusilla)Effects of Thyroid Hormones on Serum Levels of Adipokines as Studied in Patients with Differentiated Thyroid Carcinoma During Thyroxine WithdrawalRole of melanocortin signaling in the regulation of the hypothalamic–pituitary–thyroid (HPT) axisObesity drugs and their targets: correlation of mouse knockout phenotypes with drug effects in vivoThe TRH neuron: a hypothalamic integrator of energy metabolismCentral Thyrotropin-Releasing Hormone Infusion Opposes Cardiovascular and Metabolic Suppression during Caloric RestrictionMembrane transporters for thyroid hormoneRole of Thyroid Hormone Deiodination in the HypothalamusThyroid hormones as molecular determinants of thermogenesisThyroid Hormone and the Energetic Cost of Keeping Body TemperatureControl and Regulatory Mechanisms Associated with Thermogenesis in Flying Insects and BirdsHypothyroidism in rats decreases peripheral glucose utilisation, a defect partially corrected by central leptin infusionHypothyroidism - an unexpected diagnosis following emergency treatment for heatstrokeMitochondria in nonalcoholic fatty liver disease 5 August 2003Volume 139, Issue 3Page: 233KeywordsAntibioticsBacteremiaMethicillin-resistant Staphylococcus aureusNosocomial infectionsNursing homesPathogensPrevention, policy, and public healthSputumUrineVancomycin ePublished: 5 August 2003 Issue Published: 5 August 2003 CopyrightCopyright © 2003 by American College of Physicians. 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