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- W2106332326 abstract "This study was carried out to elucidate whether apoptosis and p53 can be used to stratify oral cancer patients into groups with a favorable or unfavorable response to preoperative radiation therapy. Thirty-two patients were evaluated. The apoptosis index was 1.7±0.9% in the ineffective cases, and it was significantly lower than effective cases (3.2±1.2%). While 14 of 16 effective cases (86.7%) did not express p53, 13 of 16 ineffective cases (81.3%) overexpressed p53. These results suggest that mutated p53 in tumors is associated with a poor response to radiation which may be related to evasion of apoptosis in oral cancer." @default.
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- W2106332326 date "2000-06-01" @default.
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- W2106332326 title "Apoptosis and p53 are associated with effect of preoperative radiation in oral squamous cell carcinomas" @default.
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- W2106332326 doi "https://doi.org/10.1016/s0304-3835(00)00376-1" @default.
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