FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2106342078> ?p ?o ?g. }

• W2106342078 endingPage "S34" @default.
• W2106342078 startingPage "S29" @default.
• W2106342078 abstract "Chronic venous insufficiency (CVI) is accompanied by a marked inflammatory response that is thought to contribute to the development and progression of the disorder. While compression therapy has long been considered the standard treatment for CVI, recent studies suggest that treatment with flavonoids may also be beneficial. The purpose of this review is to summarize how plant flavonoids attenuate inflammation and the immune response through their inhibition of important regulatory enzymes. Certain flavonoids are potent inhibitors of the production of prostaglandins, a group of powerful proinflammatory signaling molecules. Studies have shown that this effect is due to flavonoid inhibition of key enzymes involved in prostaglandin biosynthesis (i.e., lipoxygenase, phospholipase, and cyclooxygenase). Flavonoids also inhibit phosphodiesterases involved in cell activation. Much of this effect is upon the biosynthesis of protein cytokines that mediate adhesion of circulating leukocytes to sites of injury. The protein kinases are another class of regulatory enzymes affected by flavonoids. The inhibition of kinases is due to the competitive binding of flavonoids with ATP at catalytic sites on the enzymes. These modes of inhibition provide the mechanisms by which flavonoids inhibit the inflammation response and suggest that this class of molecules may be effective in the treatment of CVI." @default.
• W2106342078 created "2016-06-24" @default.
• W2106342078 creator A5079159368 @default.
• W2106342078 date "2000-12-01" @default.
• W2106342078 modified "2023-09-30" @default.
• W2106342078 title "Biological Properties of Flavonoids Pertaining to Inflammation" @default.
• W2106342078 cites W144641193 @default.
• W2106342078 cites W1564012501 @default.
• W2106342078 cites W1577086711 @default.
• W2106342078 cites W1807257653 @default.
• W2106342078 cites W1966766104 @default.
• W2106342078 cites W1972932252 @default.
• W2106342078 cites W1973123618 @default.
• W2106342078 cites W1973526235 @default.
• W2106342078 cites W1975084586 @default.
• W2106342078 cites W1975257561 @default.
• W2106342078 cites W1977633602 @default.
• W2106342078 cites W1978132751 @default.
• W2106342078 cites W1980506854 @default.
• W2106342078 cites W1993708945 @default.
• W2106342078 cites W1996760617 @default.
• W2106342078 cites W1998024482 @default.
• W2106342078 cites W2002889956 @default.
• W2106342078 cites W2005795522 @default.
• W2106342078 cites W2012169750 @default.
• W2106342078 cites W2017810609 @default.
• W2106342078 cites W2019398431 @default.
• W2106342078 cites W2020477110 @default.
• W2106342078 cites W2031390837 @default.
• W2106342078 cites W2036273263 @default.
• W2106342078 cites W2046279759 @default.
• W2106342078 cites W2049714951 @default.
• W2106342078 cites W2058161222 @default.
• W2106342078 cites W2060479161 @default.
• W2106342078 cites W2062399394 @default.
• W2106342078 cites W2064194276 @default.
• W2106342078 cites W2072937220 @default.
• W2106342078 cites W2076315733 @default.
• W2106342078 cites W2082458166 @default.
• W2106342078 cites W2083217753 @default.
• W2106342078 cites W2087075582 @default.
• W2106342078 cites W2097103756 @default.
• W2106342078 cites W2102715783 @default.
• W2106342078 cites W2118274268 @default.
• W2106342078 cites W2154162144 @default.
• W2106342078 cites W2155667260 @default.
• W2106342078 cites W2160653841 @default.
• W2106342078 cites W4253363877 @default.
• W2106342078 doi "https://doi.org/10.1111/j.1549-8719.2000.tb00148.x" @default.
• W2106342078 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11151968" @default.
• W2106342078 hasPublicationYear "2000" @default.
• W2106342078 type Work @default.
• W2106342078 sameAs 2106342078 @default.
• W2106342078 citedByCount "88" @default.
• W2106342078 countsByYear W21063420782012 @default.
• W2106342078 countsByYear W21063420782013 @default.
• W2106342078 countsByYear W21063420782014 @default.
• W2106342078 countsByYear W21063420782015 @default.
• W2106342078 countsByYear W21063420782016 @default.
• W2106342078 countsByYear W21063420782017 @default.
• W2106342078 countsByYear W21063420782018 @default.
• W2106342078 countsByYear W21063420782019 @default.
• W2106342078 countsByYear W21063420782020 @default.
• W2106342078 countsByYear W21063420782021 @default.
• W2106342078 countsByYear W21063420782022 @default.
• W2106342078 countsByYear W21063420782023 @default.
• W2106342078 crossrefType "journal-article" @default.
• W2106342078 hasAuthorship W2106342078A5079159368 @default.
• W2106342078 hasConcept C164027704 @default.
• W2106342078 hasConcept C181199279 @default.
• W2106342078 hasConcept C184235292 @default.
• W2106342078 hasConcept C185592680 @default.
• W2106342078 hasConcept C203014093 @default.
• W2106342078 hasConcept C2776551241 @default.
• W2106342078 hasConcept C2776914184 @default.
• W2106342078 hasConcept C2778078955 @default.
• W2106342078 hasConcept C2779689624 @default.
• W2106342078 hasConcept C2780857362 @default.
• W2106342078 hasConcept C55493867 @default.
• W2106342078 hasConcept C86803240 @default.
• W2106342078 hasConcept C90342290 @default.
• W2106342078 hasConcept C98274493 @default.
• W2106342078 hasConceptScore W2106342078C164027704 @default.
• W2106342078 hasConceptScore W2106342078C181199279 @default.
• W2106342078 hasConceptScore W2106342078C184235292 @default.
• W2106342078 hasConceptScore W2106342078C185592680 @default.
• W2106342078 hasConceptScore W2106342078C203014093 @default.
• W2106342078 hasConceptScore W2106342078C2776551241 @default.
• W2106342078 hasConceptScore W2106342078C2776914184 @default.
• W2106342078 hasConceptScore W2106342078C2778078955 @default.
• W2106342078 hasConceptScore W2106342078C2779689624 @default.
• W2106342078 hasConceptScore W2106342078C2780857362 @default.
• W2106342078 hasConceptScore W2106342078C55493867 @default.
• W2106342078 hasConceptScore W2106342078C86803240 @default.
• W2106342078 hasConceptScore W2106342078C90342290 @default.
• W2106342078 hasConceptScore W2106342078C98274493 @default.
• W2106342078 hasIssue "S1" @default.
• W2106342078 hasLocation W21063420781 @default.

• next