FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2106355635> ?p ?o ?g. }

• W2106355635 endingPage "1086" @default.
• W2106355635 startingPage "1076" @default.
• W2106355635 abstract "Benign prostatic hyperplasia (BPH) is a complex disease that is progressive in many men. BPH is commonly associated with bothersome lower urinary tract symptoms; progressive disease can also result in complications such as acute urinary retention (AUR) and BPH-related surgery. It is therefore important to identify men at increased risk of BPH progression to optimise therapy. Several factors are associated with progression, including age and prostate volume (PV). Serum prostate-specific antigen level is closely correlated with PV, making it useful for determining the risk of BPH progression. Medical therapy is the most frequently used treatment for BPH. 5-alpha-reductase inhibitors impact the underlying disease and decrease PV; this results in improved symptoms, urinary flow and quality of life, and a reduced risk of AUR and BPH-related surgery. Alpha-blockers achieve rapid symptom relief but do not reduce the overall risk of AUR or BPH-related surgery, presumably because they have no effect on PV. Combination therapy provides greater and more durable benefits than either monotherapy and is a recommended option in treatment guidelines. The Combination of Avodart and Tamsulosin (CombAT) study is currently evaluating the combination of dutasteride with tamsulosin over 4 years in a population of men at increased risk of BPH progression. A preplanned 2-year analysis has shown sustained symptom improvement with combination therapy, significantly greater than with either monotherapy. CombAT is also the first study to show benefit in improving BPH symptoms for combination therapy over the alpha-blocker, tamsulosin, from 9 months of treatment." @default.
• W2106355635 created "2016-06-24" @default.
• W2106355635 creator A5007873173 @default.
• W2106355635 creator A5043464512 @default.
• W2106355635 creator A5045922756 @default.
• W2106355635 creator A5061481176 @default.
• W2106355635 creator A5083172675 @default.
• W2106355635 creator A5064537464 @default.
• W2106355635 date "2008-05-08" @default.
• W2106355635 modified "2023-10-13" @default.
• W2106355635 title "Benign prostatic hyperplasia as a progressive disease: a guide to the risk factors and options for medical management" @default.
• W2106355635 cites W100997517 @default.
• W2106355635 cites W1524454035 @default.
• W2106355635 cites W1546910242 @default.
• W2106355635 cites W1569455139 @default.
• W2106355635 cites W1583264770 @default.
• W2106355635 cites W1966345715 @default.
• W2106355635 cites W1976070027 @default.
• W2106355635 cites W1977948413 @default.
• W2106355635 cites W1978111452 @default.
• W2106355635 cites W1979870734 @default.
• W2106355635 cites W1980309257 @default.
• W2106355635 cites W1981127873 @default.
• W2106355635 cites W1982951328 @default.
• W2106355635 cites W1999847015 @default.
• W2106355635 cites W2005166051 @default.
• W2106355635 cites W2011962188 @default.
• W2106355635 cites W2017065464 @default.
• W2106355635 cites W2020105514 @default.
• W2106355635 cites W2025055831 @default.
• W2106355635 cites W2026635055 @default.
• W2106355635 cites W2029261589 @default.
• W2106355635 cites W2029280248 @default.
• W2106355635 cites W2030698665 @default.
• W2106355635 cites W2038056618 @default.
• W2106355635 cites W2038112038 @default.
• W2106355635 cites W2042565581 @default.
• W2106355635 cites W2045486511 @default.
• W2106355635 cites W2051592657 @default.
• W2106355635 cites W2054855511 @default.
• W2106355635 cites W2066674875 @default.
• W2106355635 cites W2081313560 @default.
• W2106355635 cites W2088406017 @default.
• W2106355635 cites W2089030366 @default.
• W2106355635 cites W2090839011 @default.
• W2106355635 cites W2091895306 @default.
• W2106355635 cites W2092885298 @default.
• W2106355635 cites W2096563779 @default.
• W2106355635 cites W2106455438 @default.
• W2106355635 cites W2121759271 @default.
• W2106355635 cites W2123278711 @default.
• W2106355635 cites W2126104986 @default.
• W2106355635 cites W2135421268 @default.
• W2106355635 cites W2143802633 @default.
• W2106355635 cites W2147450987 @default.
• W2106355635 cites W2148027243 @default.
• W2106355635 cites W2151094563 @default.
• W2106355635 cites W2160699421 @default.
• W2106355635 cites W2165635016 @default.
• W2106355635 cites W2171793779 @default.
• W2106355635 cites W2331302678 @default.
• W2106355635 cites W2768448209 @default.
• W2106355635 cites W2804551733 @default.
• W2106355635 cites W2907622422 @default.
• W2106355635 cites W3135529189 @default.
• W2106355635 cites W4236163484 @default.
• W2106355635 cites W4299485640 @default.
• W2106355635 cites W4362207783 @default.
• W2106355635 doi "https://doi.org/10.1111/j.1742-1241.2008.01785.x" @default.
• W2106355635 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2440415" @default.
• W2106355635 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18479366" @default.
• W2106355635 hasPublicationYear "2008" @default.
• W2106355635 type Work @default.
• W2106355635 sameAs 2106355635 @default.
• W2106355635 citedByCount "123" @default.
• W2106355635 countsByYear W21063556352012 @default.
• W2106355635 countsByYear W21063556352013 @default.
• W2106355635 countsByYear W21063556352014 @default.
• W2106355635 countsByYear W21063556352015 @default.
• W2106355635 countsByYear W21063556352016 @default.
• W2106355635 countsByYear W21063556352017 @default.
• W2106355635 countsByYear W21063556352018 @default.
• W2106355635 countsByYear W21063556352019 @default.
• W2106355635 countsByYear W21063556352020 @default.
• W2106355635 countsByYear W21063556352021 @default.
• W2106355635 countsByYear W21063556352022 @default.
• W2106355635 countsByYear W21063556352023 @default.
• W2106355635 crossrefType "journal-article" @default.
• W2106355635 hasAuthorship W2106355635A5007873173 @default.
• W2106355635 hasAuthorship W2106355635A5043464512 @default.
• W2106355635 hasAuthorship W2106355635A5045922756 @default.
• W2106355635 hasAuthorship W2106355635A5061481176 @default.
• W2106355635 hasAuthorship W2106355635A5064537464 @default.
• W2106355635 hasAuthorship W2106355635A5083172675 @default.
• W2106355635 hasBestOaLocation W21063556351 @default.
• W2106355635 hasConcept C121608353 @default.
• W2106355635 hasConcept C126322002 @default.
• W2106355635 hasConcept C126894567 @default.

• next