FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2106361531> ?p ?o ?g. }

• W2106361531 endingPage "172" @default.
• W2106361531 startingPage "169" @default.
• W2106361531 abstract "Macrophage apoptosis plays important roles in atherosclerosis. Bcl-2 is a key cell survival molecule, but its role in macrophage apoptosis in atherosclerosis is not known. The goal herein was to determine the effect of macrophage-targeted deletion of Bcl-2 on macrophage apoptosis in atherosclerotic lesions of Apoe(-/-) mice.Bcl2(flox)-LysMCre mice were created as a model of macrophage Bcl-2 deficiency. Macrophages from these mice were more susceptible to apoptosis than those from control Bcl2(WT)-LysMCre mice. The mice were bred onto the Apoe(-/-) background and fed a Western-type diet for 4 or 10 weeks. Apoptotic cells were equally very rare in the lesions of both groups of the 4-week-diet mice, and there was no difference in lesion area. However, Bcl2(flox)-LysMCre;Apoe(-/-) plaques from the 10-week-diet protocol had a 40% to 45% increase in apoptotic cells and, in female mice, a approximately 25% increase in plaque necrosis (P<0.05) compared with Bcl2(WT)-LysMCre lesions.Macrophage Bcl-2 plays a protective role against macrophage apoptosis specifically in advanced atherosclerotic lesions of Apoe(-/-) mice." @default.
• W2106361531 created "2016-06-24" @default.
• W2106361531 creator A5027947816 @default.
• W2106361531 creator A5039333564 @default.
• W2106361531 creator A5045490604 @default.
• W2106361531 creator A5049356706 @default.
• W2106361531 creator A5052197199 @default.
• W2106361531 creator A5077497330 @default.
• W2106361531 creator A5078662102 @default.
• W2106361531 creator A5088448170 @default.
• W2106361531 date "2009-02-01" @default.
• W2106361531 modified "2023-09-24" @default.
• W2106361531 title "Brief Report: Increased Apoptosis in Advanced Atherosclerotic Lesions of <i>Apoe</i> ^−/− Mice Lacking Macrophage Bcl-2" @default.
• W2106361531 cites W1589415602 @default.
• W2106361531 cites W1944486346 @default.
• W2106361531 cites W1970037895 @default.
• W2106361531 cites W1980473071 @default.
• W2106361531 cites W1999166344 @default.
• W2106361531 cites W2019109323 @default.
• W2106361531 cites W2057330104 @default.
• W2106361531 cites W2085420819 @default.
• W2106361531 cites W2103566243 @default.
• W2106361531 cites W2115457290 @default.
• W2106361531 cites W2163327518 @default.
• W2106361531 cites W2169349825 @default.
• W2106361531 doi "https://doi.org/10.1161/atvbaha.108.176495" @default.
• W2106361531 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2731712" @default.
• W2106361531 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18988889" @default.
• W2106361531 hasPublicationYear "2009" @default.
• W2106361531 type Work @default.
• W2106361531 sameAs 2106361531 @default.
• W2106361531 citedByCount "87" @default.
• W2106361531 countsByYear W21063615312012 @default.
• W2106361531 countsByYear W21063615312013 @default.
• W2106361531 countsByYear W21063615312014 @default.
• W2106361531 countsByYear W21063615312015 @default.
• W2106361531 countsByYear W21063615312016 @default.
• W2106361531 countsByYear W21063615312017 @default.
• W2106361531 countsByYear W21063615312018 @default.
• W2106361531 countsByYear W21063615312019 @default.
• W2106361531 countsByYear W21063615312020 @default.
• W2106361531 countsByYear W21063615312021 @default.
• W2106361531 countsByYear W21063615312022 @default.
• W2106361531 countsByYear W21063615312023 @default.
• W2106361531 crossrefType "journal-article" @default.
• W2106361531 hasAuthorship W2106361531A5027947816 @default.
• W2106361531 hasAuthorship W2106361531A5039333564 @default.
• W2106361531 hasAuthorship W2106361531A5045490604 @default.
• W2106361531 hasAuthorship W2106361531A5049356706 @default.
• W2106361531 hasAuthorship W2106361531A5052197199 @default.
• W2106361531 hasAuthorship W2106361531A5077497330 @default.
• W2106361531 hasAuthorship W2106361531A5078662102 @default.
• W2106361531 hasAuthorship W2106361531A5088448170 @default.
• W2106361531 hasBestOaLocation W21063615311 @default.
• W2106361531 hasConcept C142724271 @default.
• W2106361531 hasConcept C190283241 @default.
• W2106361531 hasConcept C202751555 @default.
• W2106361531 hasConcept C203014093 @default.
• W2106361531 hasConcept C2776914184 @default.
• W2106361531 hasConcept C2779134260 @default.
• W2106361531 hasConcept C2779244956 @default.
• W2106361531 hasConcept C2781156865 @default.
• W2106361531 hasConcept C502942594 @default.
• W2106361531 hasConcept C503630168 @default.
• W2106361531 hasConcept C55493867 @default.
• W2106361531 hasConcept C57089818 @default.
• W2106361531 hasConcept C71924100 @default.
• W2106361531 hasConcept C86803240 @default.
• W2106361531 hasConceptScore W2106361531C142724271 @default.
• W2106361531 hasConceptScore W2106361531C190283241 @default.
• W2106361531 hasConceptScore W2106361531C202751555 @default.
• W2106361531 hasConceptScore W2106361531C203014093 @default.
• W2106361531 hasConceptScore W2106361531C2776914184 @default.
• W2106361531 hasConceptScore W2106361531C2779134260 @default.
• W2106361531 hasConceptScore W2106361531C2779244956 @default.
• W2106361531 hasConceptScore W2106361531C2781156865 @default.
• W2106361531 hasConceptScore W2106361531C502942594 @default.
• W2106361531 hasConceptScore W2106361531C503630168 @default.
• W2106361531 hasConceptScore W2106361531C55493867 @default.
• W2106361531 hasConceptScore W2106361531C57089818 @default.
• W2106361531 hasConceptScore W2106361531C71924100 @default.
• W2106361531 hasConceptScore W2106361531C86803240 @default.
• W2106361531 hasIssue "2" @default.
• W2106361531 hasLocation W21063615311 @default.
• W2106361531 hasLocation W21063615312 @default.
• W2106361531 hasLocation W21063615313 @default.
• W2106361531 hasLocation W21063615314 @default.
• W2106361531 hasOpenAccess W2106361531 @default.
• W2106361531 hasPrimaryLocation W21063615311 @default.
• W2106361531 hasRelatedWork W2046804643 @default.
• W2106361531 hasRelatedWork W2086326291 @default.
• W2106361531 hasRelatedWork W2106361531 @default.
• W2106361531 hasRelatedWork W2160208825 @default.
• W2106361531 hasRelatedWork W2163287848 @default.
• W2106361531 hasRelatedWork W2343669194 @default.
• W2106361531 hasRelatedWork W2356400710 @default.
• W2106361531 hasRelatedWork W2380715989 @default.
• W2106361531 hasRelatedWork W2576982802 @default.

• next