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• W2106403755 startingPage "280" @default.
• W2106403755 abstract "Some patients with early-onset Alzheimer's disease (AD) present with a distinct phenotype. Typically, the first and most salient characteristic of AD is episodic memory impairment. A few patients, however, present with focal cortical, non-memory symptoms, such as difficulties with language, visuospatial, or executive functions. These presentations are associated with specific patterns of atrophy and frequently with a young age at onset. Age is not, however, the only determinant of phenotype; underlying factors, especially genetic factors, seem also to affect phenotype and predispose patients to younger or older age at onset. Importantly, patients with atypical early-onset disease seldom carry the APOE ɛ4 allele, which is the most important risk factor for lowering the age of onset in patients with AD. Additionally, theAPOE ɛ4 genotype seems to predispose patients to vulnerability in the medial temporal areas, which leads to memory loss. Conversely, patients negative for the APOE ɛ4 allele and with early-onset AD are more likely to be predisposed to vulnerability of cerebral networks beyond the medial temporal lobes. Other factors are probably involved in determining the pattern of atrophy, but these are currently unknown." @default.
• W2106403755 created "2016-06-24" @default.
• W2106403755 creator A5018836358 @default.
• W2106403755 creator A5025870220 @default.
• W2106403755 creator A5038926287 @default.
• W2106403755 creator A5059183048 @default.
• W2106403755 date "2011-03-01" @default.
• W2106403755 modified "2023-10-11" @default.
• W2106403755 title "Early-onset versus late-onset Alzheimer's disease: the case of the missing APOE ɛ4 allele" @default.
• W2106403755 cites W1486380975 @default.
• W2106403755 cites W1539826184 @default.
• W2106403755 cites W1966283817 @default.
• W2106403755 cites W1968954730 @default.
• W2106403755 cites W1969431952 @default.
• W2106403755 cites W1971565607 @default.
• W2106403755 cites W1978522491 @default.
• W2106403755 cites W1979587499 @default.
• W2106403755 cites W1980727483 @default.
• W2106403755 cites W1982097130 @default.
• W2106403755 cites W1989178832 @default.
• W2106403755 cites W1989274511 @default.
• W2106403755 cites W1989451265 @default.
• W2106403755 cites W1994514180 @default.
• W2106403755 cites W2001688761 @default.
• W2106403755 cites W2004284975 @default.
• W2106403755 cites W2007350172 @default.
• W2106403755 cites W2007929153 @default.
• W2106403755 cites W2008002833 @default.
• W2106403755 cites W2009088633 @default.
• W2106403755 cites W2010827885 @default.
• W2106403755 cites W2010925911 @default.
• W2106403755 cites W2014247959 @default.
• W2106403755 cites W2014459814 @default.
• W2106403755 cites W2014930223 @default.
• W2106403755 cites W2017456650 @default.
• W2106403755 cites W2017654651 @default.
• W2106403755 cites W2017859333 @default.
• W2106403755 cites W2021913585 @default.
• W2106403755 cites W2023131797 @default.
• W2106403755 cites W2028588822 @default.
• W2106403755 cites W2030619286 @default.
• W2106403755 cites W2033221372 @default.
• W2106403755 cites W2033572099 @default.
• W2106403755 cites W2035057032 @default.
• W2106403755 cites W2041378923 @default.
• W2106403755 cites W2041394188 @default.
• W2106403755 cites W2042795487 @default.
• W2106403755 cites W2044565580 @default.
• W2106403755 cites W2050190016 @default.
• W2106403755 cites W2050255138 @default.
• W2106403755 cites W2052742260 @default.
• W2106403755 cites W2053116984 @default.
• W2106403755 cites W2053215546 @default.
• W2106403755 cites W2056966839 @default.
• W2106403755 cites W2057323230 @default.
• W2106403755 cites W2058949527 @default.
• W2106403755 cites W2059315042 @default.
• W2106403755 cites W2060492349 @default.
• W2106403755 cites W2061880941 @default.
• W2106403755 cites W2066977853 @default.
• W2106403755 cites W2068441330 @default.
• W2106403755 cites W2069461843 @default.
• W2106403755 cites W2069903612 @default.
• W2106403755 cites W2074109912 @default.
• W2106403755 cites W2074349167 @default.
• W2106403755 cites W2075993061 @default.
• W2106403755 cites W2077399174 @default.
• W2106403755 cites W2078718001 @default.
• W2106403755 cites W2079448664 @default.
• W2106403755 cites W2081138810 @default.
• W2106403755 cites W2084725130 @default.
• W2106403755 cites W2087610081 @default.
• W2106403755 cites W2089249114 @default.
• W2106403755 cites W2089760569 @default.
• W2106403755 cites W2096570098 @default.
• W2106403755 cites W2100988134 @default.
• W2106403755 cites W2102552130 @default.
• W2106403755 cites W2104750661 @default.
• W2106403755 cites W2104954974 @default.
• W2106403755 cites W2105068724 @default.
• W2106403755 cites W2105110308 @default.
• W2106403755 cites W2106217904 @default.
• W2106403755 cites W2108475007 @default.
• W2106403755 cites W2110003880 @default.
• W2106403755 cites W2112957305 @default.
• W2106403755 cites W2114791522 @default.
• W2106403755 cites W2115474152 @default.
• W2106403755 cites W2116608586 @default.
• W2106403755 cites W2118993423 @default.
• W2106403755 cites W2120068364 @default.
• W2106403755 cites W2134379460 @default.
• W2106403755 cites W2134766819 @default.
• W2106403755 cites W2136978757 @default.
• W2106403755 cites W2137897073 @default.
• W2106403755 cites W2140218187 @default.
• W2106403755 cites W2142244150 @default.
• W2106403755 cites W2142287887 @default.
• W2106403755 cites W2143060109 @default.

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