FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2106543247> ?p ?o ?g. }

• W2106543247 endingPage "2791" @default.
• W2106543247 startingPage "2779" @default.
• W2106543247 abstract "The RING-type E3 ligase, Keep on Going (KEG), is required for early seedling establishment in Arabidopsis thaliana. Post-germination, KEG negatively regulates abscisic acid (ABA) signalling by targeting Abscisic Acid Insensitive 5 (ABI5) for ubiquitination and subsequent degradation. Previous reports suggest that the role of KEG during early seedling development is not limited to regulation of ABI5 abundance. Using a yeast two-hybrid screen, this study identified Calcineurin B-like Interacting Protein Kinase (CIPK) 26 as a KEG-interacting protein. In vitro pull-down and in planta bimolecular fluorescence complementation assays confirmed the interactions between CIPK26 and KEG. In planta experiments demonstrated that CIPK26 was ubiquitinated and degraded via the 26S proteasome. It was also found that turnover of CIPK26 was increased when KEG protein levels were elevated, suggesting that the RING-type E3 ligase is involved in targeting CIPK26 for degradation. CIPK26 was found to interact with the ABA signalling components ABI1, ABI2, and ABI5. In addition, CIPK26 was capable of phosphorylating ABI5 in vitro. Consistent with a role in ABA signalling, overexpression of CIPK26 increased the sensitivity of germinating seeds to the inhibitory effects of ABA. The data presented in this report suggest that KEG mediates the proteasomal degradation of CIPK26 and that CIPK26 is part of the ABA signalling network." @default.
• W2106543247 created "2016-06-24" @default.
• W2106543247 creator A5012227517 @default.
• W2106543247 creator A5019259869 @default.
• W2106543247 creator A5027499238 @default.
• W2106543247 creator A5063820246 @default.
• W2106543247 creator A5071985886 @default.
• W2106543247 date "2013-05-08" @default.
• W2106543247 modified "2023-10-13" @default.
• W2106543247 title "Arabidopsis CIPK26 interacts with KEG, components of the ABA signalling network and is degraded by the ubiquitin–proteasome system" @default.
• W2106543247 cites W1891374880 @default.
• W2106543247 cites W1922705769 @default.
• W2106543247 cites W1969757511 @default.
• W2106543247 cites W1975110054 @default.
• W2106543247 cites W1986627314 @default.
• W2106543247 cites W1987807183 @default.
• W2106543247 cites W1997038372 @default.
• W2106543247 cites W1997490422 @default.
• W2106543247 cites W2002821316 @default.
• W2106543247 cites W2005458067 @default.
• W2106543247 cites W2009748326 @default.
• W2106543247 cites W2013090884 @default.
• W2106543247 cites W2017472434 @default.
• W2106543247 cites W2034940025 @default.
• W2106543247 cites W2038593526 @default.
• W2106543247 cites W2060396596 @default.
• W2106543247 cites W2062937490 @default.
• W2106543247 cites W2078929441 @default.
• W2106543247 cites W2086473109 @default.
• W2106543247 cites W2094547279 @default.
• W2106543247 cites W2097305183 @default.
• W2106543247 cites W2098115340 @default.
• W2106543247 cites W2100126837 @default.
• W2106543247 cites W2106249858 @default.
• W2106543247 cites W2113160145 @default.
• W2106543247 cites W2113656016 @default.
• W2106543247 cites W2116122104 @default.
• W2106543247 cites W2117599191 @default.
• W2106543247 cites W2123393582 @default.
• W2106543247 cites W2130438091 @default.
• W2106543247 cites W2131636056 @default.
• W2106543247 cites W2136145421 @default.
• W2106543247 cites W2137985960 @default.
• W2106543247 cites W2141429272 @default.
• W2106543247 cites W2142711902 @default.
• W2106543247 cites W2145048774 @default.
• W2106543247 cites W2149402795 @default.
• W2106543247 cites W2156166308 @default.
• W2106543247 cites W2160252178 @default.
• W2106543247 cites W2163448850 @default.
• W2106543247 cites W2165902959 @default.
• W2106543247 cites W2167255717 @default.
• W2106543247 cites W2168455728 @default.
• W2106543247 cites W2169915963 @default.
• W2106543247 cites W2170154480 @default.
• W2106543247 cites W32924917 @default.
• W2106543247 doi "https://doi.org/10.1093/jxb/ert123" @default.
• W2106543247 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3697954" @default.
• W2106543247 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23658427" @default.
• W2106543247 hasPublicationYear "2013" @default.
• W2106543247 type Work @default.
• W2106543247 sameAs 2106543247 @default.
• W2106543247 citedByCount "120" @default.
• W2106543247 countsByYear W21065432472013 @default.
• W2106543247 countsByYear W21065432472014 @default.
• W2106543247 countsByYear W21065432472015 @default.
• W2106543247 countsByYear W21065432472016 @default.
• W2106543247 countsByYear W21065432472017 @default.
• W2106543247 countsByYear W21065432472018 @default.
• W2106543247 countsByYear W21065432472019 @default.
• W2106543247 countsByYear W21065432472020 @default.
• W2106543247 countsByYear W21065432472021 @default.
• W2106543247 countsByYear W21065432472022 @default.
• W2106543247 countsByYear W21065432472023 @default.
• W2106543247 crossrefType "journal-article" @default.
• W2106543247 hasAuthorship W2106543247A5012227517 @default.
• W2106543247 hasAuthorship W2106543247A5019259869 @default.
• W2106543247 hasAuthorship W2106543247A5027499238 @default.
• W2106543247 hasAuthorship W2106543247A5063820246 @default.
• W2106543247 hasAuthorship W2106543247A5071985886 @default.
• W2106543247 hasBestOaLocation W21065432471 @default.
• W2106543247 hasConcept C104317684 @default.
• W2106543247 hasConcept C123243835 @default.
• W2106543247 hasConcept C134459356 @default.
• W2106543247 hasConcept C143065580 @default.
• W2106543247 hasConcept C25602115 @default.
• W2106543247 hasConcept C27740335 @default.
• W2106543247 hasConcept C2775988993 @default.
• W2106543247 hasConcept C2779222958 @default.
• W2106543247 hasConcept C2779491563 @default.
• W2106543247 hasConcept C2779591172 @default.
• W2106543247 hasConcept C2992195973 @default.
• W2106543247 hasConcept C55493867 @default.
• W2106543247 hasConcept C86803240 @default.
• W2106543247 hasConcept C95444343 @default.
• W2106543247 hasConceptScore W2106543247C104317684 @default.
• W2106543247 hasConceptScore W2106543247C123243835 @default.
• W2106543247 hasConceptScore W2106543247C134459356 @default.

• next