FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2106552103> ?p ?o ?g. }

• W2106552103 endingPage "e140" @default.
• W2106552103 startingPage "e140" @default.
• W2106552103 abstract "We describe here a mass spectrometry (MS)-based analytical platform of RNA, which combines direct nano-flow reversed-phase liquid chromatography (RPLC) on a spray tip column and a high-resolution LTQ-Orbitrap mass spectrometer. Operating RPLC under a very low flow rate with volatile solvents and MS in the negative mode, we could estimate highly accurate mass values sufficient to predict the nucleotide composition of a approximately 21-nucleotide small interfering RNA, detect post-transcriptional modifications in yeast tRNA, and perform collision-induced dissociation/tandem MS-based structural analysis of nucleolytic fragments of RNA at a sub-femtomole level. Importantly, the method allowed the identification and chemical analysis of small RNAs in ribonucleoprotein (RNP) complex, such as the pre-spliceosomal RNP complex, which was pulled down from cultured cells with a tagged protein cofactor as bait. We have recently developed a unique genome-oriented database search engine, Ariadne, which allows tandem MS-based identification of RNAs in biological samples. Thus, the method presented here has broad potential for automated analysis of RNA; it complements conventional molecular biology-based techniques and is particularly suited for simultaneous analysis of the composition, structure, interaction, and dynamics of RNA and protein components in various cellular RNP complexes." @default.
• W2106552103 created "2016-06-24" @default.
• W2106552103 creator A5011865780 @default.
• W2106552103 creator A5019620890 @default.
• W2106552103 creator A5021428297 @default.
• W2106552103 creator A5024186970 @default.
• W2106552103 creator A5051273148 @default.
• W2106552103 creator A5077124170 @default.
• W2106552103 creator A5079654577 @default.
• W2106552103 creator A5084039663 @default.
• W2106552103 date "2009-09-09" @default.
• W2106552103 modified "2023-10-14" @default.
• W2106552103 title "An analytical platform for mass spectrometry-based identification and chemical analysis of RNA in ribonucleoprotein complexes" @default.
• W2106552103 cites W1532644721 @default.
• W2106552103 cites W1556249430 @default.
• W2106552103 cites W1841435798 @default.
• W2106552103 cites W1967404904 @default.
• W2106552103 cites W1970070502 @default.
• W2106552103 cites W1970908974 @default.
• W2106552103 cites W1975390562 @default.
• W2106552103 cites W1976043435 @default.
• W2106552103 cites W1979566118 @default.
• W2106552103 cites W1985863431 @default.
• W2106552103 cites W1988391179 @default.
• W2106552103 cites W1989547144 @default.
• W2106552103 cites W1990214042 @default.
• W2106552103 cites W1991284817 @default.
• W2106552103 cites W1997517873 @default.
• W2106552103 cites W2000904576 @default.
• W2106552103 cites W2002025698 @default.
• W2106552103 cites W2006124679 @default.
• W2106552103 cites W2010102836 @default.
• W2106552103 cites W2016548334 @default.
• W2106552103 cites W2017570593 @default.
• W2106552103 cites W2020747171 @default.
• W2106552103 cites W2022831271 @default.
• W2106552103 cites W2023164416 @default.
• W2106552103 cites W2025612803 @default.
• W2106552103 cites W2031483194 @default.
• W2106552103 cites W2033045608 @default.
• W2106552103 cites W2033583580 @default.
• W2106552103 cites W2034947201 @default.
• W2106552103 cites W2035398832 @default.
• W2106552103 cites W2041703851 @default.
• W2106552103 cites W2042306236 @default.
• W2106552103 cites W2042714411 @default.
• W2106552103 cites W2044586246 @default.
• W2106552103 cites W2045193818 @default.
• W2106552103 cites W2047529648 @default.
• W2106552103 cites W2057162139 @default.
• W2106552103 cites W2057412586 @default.
• W2106552103 cites W2060390444 @default.
• W2106552103 cites W2063041271 @default.
• W2106552103 cites W2069393978 @default.
• W2106552103 cites W2069815887 @default.
• W2106552103 cites W2071753136 @default.
• W2106552103 cites W2073424121 @default.
• W2106552103 cites W2073688200 @default.
• W2106552103 cites W2074183834 @default.
• W2106552103 cites W2079461444 @default.
• W2106552103 cites W2082300861 @default.
• W2106552103 cites W2082386961 @default.
• W2106552103 cites W2085954575 @default.
• W2106552103 cites W2088017477 @default.
• W2106552103 cites W2091576301 @default.
• W2106552103 cites W2093629039 @default.
• W2106552103 cites W2096433880 @default.
• W2106552103 cites W2100573143 @default.
• W2106552103 cites W2104191998 @default.
• W2106552103 cites W2104496647 @default.
• W2106552103 cites W2106305155 @default.
• W2106552103 cites W2108787892 @default.
• W2106552103 cites W2110277124 @default.
• W2106552103 cites W2110886961 @default.
• W2106552103 cites W2120353932 @default.
• W2106552103 cites W2121661890 @default.
• W2106552103 cites W2122885571 @default.
• W2106552103 cites W2126219914 @default.
• W2106552103 cites W2129776684 @default.
• W2106552103 cites W2136615690 @default.
• W2106552103 cites W2137557128 @default.
• W2106552103 cites W2140995557 @default.
• W2106552103 cites W2149676146 @default.
• W2106552103 cites W2152956996 @default.
• W2106552103 cites W2157099873 @default.
• W2106552103 cites W2161355984 @default.
• W2106552103 cites W2162682342 @default.
• W2106552103 cites W2492456842 @default.
• W2106552103 cites W2917136151 @default.
• W2106552103 doi "https://doi.org/10.1093/nar/gkp732" @default.
• W2106552103 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2790879" @default.
• W2106552103 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19740761" @default.
• W2106552103 hasPublicationYear "2009" @default.
• W2106552103 type Work @default.
• W2106552103 sameAs 2106552103 @default.
• W2106552103 citedByCount "50" @default.
• W2106552103 countsByYear W21065521032012 @default.
• W2106552103 countsByYear W21065521032013 @default.

• next