FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2106604563> ?p ?o ?g. }

• W2106604563 endingPage "542" @default.
• W2106604563 startingPage "535" @default.
• W2106604563 abstract "A series of 76 cases of gastrointestinal tract endocrine tumors, including 21 poorly differentiated endocrine carcinomas (PDECs, small cell carcinomas) and 55 well-differentiated endocrine neoplasms (WDENs, carcinoids), 18 metastatic and 37 nonmetastatic rectal carcinoids, were examined by immunohistochemical analysis for p16INK4a, cyclin D1, and retinoblastoma protein (pRB) expression. Overexpression of p16INK4a was noted in 16 (76%) of the PDECs and none of the WDENs (P < .0001). Loss of pRB expression was demonstrated in 14 (67%) of the PDECs and 17 (31%) of the WDENs (P = .004). Overexpression of cyclin D1 was noted in 49 (89%) of the WDENs and 3 (14%) of the PDECs (P < .0001). Loss of pRB expression was noted in 11 (61%) of 18 metastatic WDENs and only 6 (16%) of 37 nonmetastatic WDENs (P = .001). The p16INK4a/cyclin D1/pRB pathway was altered in gastrointestinal tract endocrine tumors, and the loss of expression of pRB may be helpful in identifying patients at high risk of metastasis in rectal WDENs." @default.
• W2106604563 created "2016-06-24" @default.
• W2106604563 creator A5010425229 @default.
• W2106604563 creator A5024262449 @default.
• W2106604563 creator A5029962699 @default.
• W2106604563 creator A5039307730 @default.
• W2106604563 creator A5069123703 @default.
• W2106604563 creator A5073663097 @default.
• W2106604563 date "2008-10-01" @default.
• W2106604563 modified "2023-10-16" @default.
• W2106604563 title "Alterations in the<i>p16</i><i>^INK4a</i><i>/Cyclin D1/RB</i>Pathway in Gastrointestinal Tract Endocrine Tumors" @default.
• W2106604563 cites W1489229313 @default.
• W2106604563 cites W1964390522 @default.
• W2106604563 cites W1971863507 @default.
• W2106604563 cites W1973191748 @default.
• W2106604563 cites W1977727795 @default.
• W2106604563 cites W1987025782 @default.
• W2106604563 cites W1990318166 @default.
• W2106604563 cites W1990509102 @default.
• W2106604563 cites W1996339349 @default.
• W2106604563 cites W2001956505 @default.
• W2106604563 cites W2011566438 @default.
• W2106604563 cites W2011761477 @default.
• W2106604563 cites W2026030746 @default.
• W2106604563 cites W2032953029 @default.
• W2106604563 cites W2053114741 @default.
• W2106604563 cites W2054794990 @default.
• W2106604563 cites W2056959168 @default.
• W2106604563 cites W2060012478 @default.
• W2106604563 cites W2061985406 @default.
• W2106604563 cites W2080448046 @default.
• W2106604563 cites W2081412587 @default.
• W2106604563 cites W2088357353 @default.
• W2106604563 cites W2093104063 @default.
• W2106604563 cites W2093364695 @default.
• W2106604563 cites W2103043986 @default.
• W2106604563 cites W2140335303 @default.
• W2106604563 cites W2143578264 @default.
• W2106604563 cites W2153586332 @default.
• W2106604563 cites W2170054665 @default.
• W2106604563 cites W2330621493 @default.
• W2106604563 cites W2512906422 @default.
• W2106604563 cites W259875475 @default.
• W2106604563 cites W624674342 @default.
• W2106604563 doi "https://doi.org/10.1309/tllvxk9hva89chpe" @default.
• W2106604563 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18794045" @default.
• W2106604563 hasPublicationYear "2008" @default.
• W2106604563 type Work @default.
• W2106604563 sameAs 2106604563 @default.
• W2106604563 citedByCount "18" @default.
• W2106604563 countsByYear W21066045632012 @default.
• W2106604563 countsByYear W21066045632014 @default.
• W2106604563 countsByYear W21066045632015 @default.
• W2106604563 countsByYear W21066045632016 @default.
• W2106604563 countsByYear W21066045632020 @default.
• W2106604563 countsByYear W21066045632021 @default.
• W2106604563 countsByYear W21066045632022 @default.
• W2106604563 countsByYear W21066045632023 @default.
• W2106604563 crossrefType "journal-article" @default.
• W2106604563 hasAuthorship W2106604563A5010425229 @default.
• W2106604563 hasAuthorship W2106604563A5024262449 @default.
• W2106604563 hasAuthorship W2106604563A5029962699 @default.
• W2106604563 hasAuthorship W2106604563A5039307730 @default.
• W2106604563 hasAuthorship W2106604563A5069123703 @default.
• W2106604563 hasAuthorship W2106604563A5073663097 @default.
• W2106604563 hasBestOaLocation W21066045631 @default.
• W2106604563 hasConcept C103395026 @default.
• W2106604563 hasConcept C104317684 @default.
• W2106604563 hasConcept C11882975 @default.
• W2106604563 hasConcept C121608353 @default.
• W2106604563 hasConcept C126322002 @default.
• W2106604563 hasConcept C142724271 @default.
• W2106604563 hasConcept C143998085 @default.
• W2106604563 hasConcept C199835354 @default.
• W2106604563 hasConcept C204232928 @default.
• W2106604563 hasConcept C2776062698 @default.
• W2106604563 hasConcept C2779013556 @default.
• W2106604563 hasConcept C2780103800 @default.
• W2106604563 hasConcept C2780512811 @default.
• W2106604563 hasConcept C29537977 @default.
• W2106604563 hasConcept C46699223 @default.
• W2106604563 hasConcept C502942594 @default.
• W2106604563 hasConcept C526805850 @default.
• W2106604563 hasConcept C55493867 @default.
• W2106604563 hasConcept C71315377 @default.
• W2106604563 hasConcept C71924100 @default.
• W2106604563 hasConcept C86803240 @default.
• W2106604563 hasConcept C9743823 @default.
• W2106604563 hasConceptScore W2106604563C103395026 @default.
• W2106604563 hasConceptScore W2106604563C104317684 @default.
• W2106604563 hasConceptScore W2106604563C11882975 @default.
• W2106604563 hasConceptScore W2106604563C121608353 @default.
• W2106604563 hasConceptScore W2106604563C126322002 @default.
• W2106604563 hasConceptScore W2106604563C142724271 @default.
• W2106604563 hasConceptScore W2106604563C143998085 @default.
• W2106604563 hasConceptScore W2106604563C199835354 @default.
• W2106604563 hasConceptScore W2106604563C204232928 @default.
• W2106604563 hasConceptScore W2106604563C2776062698 @default.

• next