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• W2106607837 abstract "The Triggering Receptors Expressed on Myeloid cells (TREM) are a family of cell-surface molecules that control inflammation, bone homeostasis, neurological development and blood coagulation. TREM-1 and TREM-2, the best-characterized receptors so far, play divergent roles in several infectious diseases. In the intestine, TREM-1 is highly expressed by macrophages, contributing to inflammatory bowel disease (IBD) pathogenesis. Contrary to current understanding, TREM-2 also promotes inflammation in IBD by fueling dendritic cell functions. This review will focus specifically on recent insights into the role of TREM proteins in IBD development, and discuss opportunities for novel treatment approaches." @default.
• W2106607837 created "2016-06-24" @default.
• W2106607837 creator A5029407987 @default.
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• W2106607837 date "2014-10-28" @default.
• W2106607837 modified "2023-10-16" @default.
• W2106607837 title "The triggering receptor expressed on myeloid cells (TREM) in inflammatory bowel disease pathogenesis" @default.
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• W2106607837 doi "https://doi.org/10.1186/s12967-014-0293-z" @default.
• W2106607837 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4231187" @default.
• W2106607837 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25347935" @default.
• W2106607837 hasPublicationYear "2014" @default.
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