FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2106641526> ?p ?o ?g. }

• W2106641526 abstract "Adefovir dipivoxil (ADV) is a nucleotide analogue that is known to be effective for lamivudine-resistant hepatitis B virus (HBV) mutants as well as wild-type HBV. The aim of this study is to assess the efficacy of ADV against lamivudine-resistant genotype C HBV mutants.Thirty-five patients with breakthrough hepatitis due to lamivudine-resistant HBV received ADV 10 mg daily with discontinuation of lamivudine. Quantitative HBV DNA, HBeAg, liver function test including alanine aminotransferase (ALT) was checked every 4-12 weeks to evaluate the efficacy of ADV.ADV was administered for a median of 48 weeks (range: 24-120 weeks). The rate of serum HBV DNA loss was 68.6%, 80.0%, 84.0%, and 88.2% at weeks 12, 24, 36, and 48, respectively. The rate of serum HBeAg seroconversion was 8.3% and 14.3% at weeks 24 and 48, respectively. The rate of serum ALT normalization at week 48 was 70.6%. Within 32 weeks after stopping ADV therapy, serum HBV DNA levels increased to a median of 378.9 pg/ml in 88.9% of patients, who were treated for a median of 40 weeks. Moreover, in some patients, the ALT level increased to more than five times the upper limit of normal.Administration of ADV is an effective option for the treatment of patients with lamivudine-resistant genotype C HBV infection." @default.
• W2106641526 created "2016-06-24" @default.
• W2106641526 creator A5019884554 @default.
• W2106641526 creator A5020060980 @default.
• W2106641526 creator A5032888224 @default.
• W2106641526 creator A5042826784 @default.
• W2106641526 creator A5048607899 @default.
• W2106641526 creator A5054417741 @default.
• W2106641526 creator A5071295748 @default.
• W2106641526 creator A5087390711 @default.
• W2106641526 creator A5088626105 @default.
• W2106641526 date "2007-02-01" @default.
• W2106641526 modified "2023-09-24" @default.
• W2106641526 title "Efficacy of adefovir dipivoxil in the treatment of lamivudine-resistant hepatitis B virus genotype C infection" @default.
• W2106641526 cites W1597477033 @default.
• W2106641526 cites W1964242359 @default.
• W2106641526 cites W1965258712 @default.
• W2106641526 cites W1965747579 @default.
• W2106641526 cites W1980912700 @default.
• W2106641526 cites W1985577568 @default.
• W2106641526 cites W2007423548 @default.
• W2106641526 cites W2027280548 @default.
• W2106641526 cites W2049234248 @default.
• W2106641526 cites W2057705273 @default.
• W2106641526 cites W2058388169 @default.
• W2106641526 cites W2093604720 @default.
• W2106641526 cites W2112150016 @default.
• W2106641526 cites W2124012164 @default.
• W2106641526 cites W2125312312 @default.
• W2106641526 cites W2137544368 @default.
• W2106641526 cites W2161280033 @default.
• W2106641526 cites W2393327590 @default.
• W2106641526 doi "https://doi.org/10.1111/j.1478-3231.2006.01407.x" @default.
• W2106641526 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17241380" @default.
• W2106641526 hasPublicationYear "2007" @default.
• W2106641526 type Work @default.
• W2106641526 sameAs 2106641526 @default.
• W2106641526 citedByCount "6" @default.
• W2106641526 countsByYear W21066415262016 @default.
• W2106641526 countsByYear W21066415262018 @default.
• W2106641526 crossrefType "journal-article" @default.
• W2106641526 hasAuthorship W2106641526A5019884554 @default.
• W2106641526 hasAuthorship W2106641526A5020060980 @default.
• W2106641526 hasAuthorship W2106641526A5032888224 @default.
• W2106641526 hasAuthorship W2106641526A5042826784 @default.
• W2106641526 hasAuthorship W2106641526A5048607899 @default.
• W2106641526 hasAuthorship W2106641526A5054417741 @default.
• W2106641526 hasAuthorship W2106641526A5071295748 @default.
• W2106641526 hasAuthorship W2106641526A5087390711 @default.
• W2106641526 hasAuthorship W2106641526A5088626105 @default.
• W2106641526 hasConcept C104317684 @default.
• W2106641526 hasConcept C126322002 @default.
• W2106641526 hasConcept C135763542 @default.
• W2106641526 hasConcept C159047783 @default.
• W2106641526 hasConcept C2522874641 @default.
• W2106641526 hasConcept C2775940106 @default.
• W2106641526 hasConcept C2776175608 @default.
• W2106641526 hasConcept C2777382497 @default.
• W2106641526 hasConcept C2777410769 @default.
• W2106641526 hasConcept C2777451964 @default.
• W2106641526 hasConcept C2777869810 @default.
• W2106641526 hasConcept C2779517838 @default.
• W2106641526 hasConcept C2780593183 @default.
• W2106641526 hasConcept C2992208098 @default.
• W2106641526 hasConcept C55493867 @default.
• W2106641526 hasConcept C71924100 @default.
• W2106641526 hasConcept C86803240 @default.
• W2106641526 hasConcept C90924648 @default.
• W2106641526 hasConceptScore W2106641526C104317684 @default.
• W2106641526 hasConceptScore W2106641526C126322002 @default.
• W2106641526 hasConceptScore W2106641526C135763542 @default.
• W2106641526 hasConceptScore W2106641526C159047783 @default.
• W2106641526 hasConceptScore W2106641526C2522874641 @default.
• W2106641526 hasConceptScore W2106641526C2775940106 @default.
• W2106641526 hasConceptScore W2106641526C2776175608 @default.
• W2106641526 hasConceptScore W2106641526C2777382497 @default.
• W2106641526 hasConceptScore W2106641526C2777410769 @default.
• W2106641526 hasConceptScore W2106641526C2777451964 @default.
• W2106641526 hasConceptScore W2106641526C2777869810 @default.
• W2106641526 hasConceptScore W2106641526C2779517838 @default.
• W2106641526 hasConceptScore W2106641526C2780593183 @default.
• W2106641526 hasConceptScore W2106641526C2992208098 @default.
• W2106641526 hasConceptScore W2106641526C55493867 @default.
• W2106641526 hasConceptScore W2106641526C71924100 @default.
• W2106641526 hasConceptScore W2106641526C86803240 @default.
• W2106641526 hasConceptScore W2106641526C90924648 @default.
• W2106641526 hasLocation W21066415261 @default.
• W2106641526 hasLocation W21066415262 @default.
• W2106641526 hasOpenAccess W2106641526 @default.
• W2106641526 hasPrimaryLocation W21066415261 @default.
• W2106641526 hasRelatedWork W2350055268 @default.
• W2106641526 hasRelatedWork W2361783070 @default.
• W2106641526 hasRelatedWork W2363757513 @default.
• W2106641526 hasRelatedWork W2366294606 @default.
• W2106641526 hasRelatedWork W2372446678 @default.
• W2106641526 hasRelatedWork W2382309574 @default.
• W2106641526 hasRelatedWork W2390789776 @default.
• W2106641526 hasRelatedWork W2392267883 @default.
• W2106641526 hasRelatedWork W3030341579 @default.
• W2106641526 hasRelatedWork W3032888043 @default.

• next