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- W2106656273 abstract "Dysprosium-165-ferric hydroxide macroaggregates (165Dy-FHMA) was used as an agent of radiation synovectomy in an antigen-induced arthritis model in New Zealand white rabbits. Animals were killed up to 6 months after treatment. 165Dy-FHMA was found to have a potent but temporary antiinflammatory effect on synovium for up to 3 months after treatment. Treated knees also showed significant preservation of articular cartilage architecture and proteoglycan content compared with untreated controls, but only during the first 3 months after treatment. In animals killed 3 and 6 months after treatment there were only minimal differences between the treated and untreated knees, indicating that the antiinflammatory effects on synovial tissue and articular cartilage preservation were not sustained." @default.
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- W2106656273 date "1989-01-01" @default.
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- W2106656273 title "Treatment of antigen-induced arthritis in rabbits with dysprosium-165-ferric hydroxide macroaggregates" @default.
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- W2106656273 doi "https://doi.org/10.1002/jor.1100070108" @default.
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