Matches in SemOpenAlex for { <https://semopenalex.org/work/W2106687572> ?p ?o ?g. }
- W2106687572 endingPage "112" @default.
- W2106687572 startingPage "105" @default.
- W2106687572 abstract "Moderate consumption of natural dietary polyphenolic compounds can reduce the risk of cardiovascular diseases. Here we investigated the protective effects of delphinidin against oxidized low-density lipoprotein (oxLDL)-induced damage in human umbilical vein endothelial cells (HUVECs). The MTT assay showed that 2h pre-incubation with delphinidin markedly restored the oxLDL-induced viability loss in HUVECs in a concentration-dependent manner. This effect was accompanied by a significant decrease in intracellular reactive oxygen species. Moreover, delphinidin imposed preventive effects on suppressing the production of lipid peroxidation, restoring the activities of endogenous antioxidants, and increasing the level of nitric oxide. Pre-incubation of delphinidin with HUVECs led to the reduction of apoptosis. Finally, delphinidin can efficiently prevent the down-regulation of Bcl-2 protein and up-regulation of Bax protein. Together, our findings suggest that delphinidin can effectively protect HUVECs against oxidative stress induced by oxLDL, which may be important for preventing both plaque development and stability in atherosclerosis." @default.
- W2106687572 created "2016-06-24" @default.
- W2106687572 creator A5006613124 @default.
- W2106687572 creator A5034471264 @default.
- W2106687572 creator A5042572280 @default.
- W2106687572 creator A5051198143 @default.
- W2106687572 creator A5069374998 @default.
- W2106687572 creator A5082703185 @default.
- W2106687572 creator A5084685500 @default.
- W2106687572 date "2010-01-01" @default.
- W2106687572 modified "2023-10-18" @default.
- W2106687572 title "Delphinidin attenuates stress injury induced by oxidized low-density lipoprotein in human umbilical vein endothelial cells" @default.
- W2106687572 cites W1964599275 @default.
- W2106687572 cites W1964617786 @default.
- W2106687572 cites W1964720110 @default.
- W2106687572 cites W1965261340 @default.
- W2106687572 cites W1971510408 @default.
- W2106687572 cites W1973368080 @default.
- W2106687572 cites W1975202491 @default.
- W2106687572 cites W1976476542 @default.
- W2106687572 cites W1977213671 @default.
- W2106687572 cites W1979399988 @default.
- W2106687572 cites W1980696093 @default.
- W2106687572 cites W1981143549 @default.
- W2106687572 cites W1992152105 @default.
- W2106687572 cites W2000342638 @default.
- W2106687572 cites W2001880177 @default.
- W2106687572 cites W2012458878 @default.
- W2106687572 cites W2013430931 @default.
- W2106687572 cites W2015620155 @default.
- W2106687572 cites W2024563812 @default.
- W2106687572 cites W2026341813 @default.
- W2106687572 cites W2026785870 @default.
- W2106687572 cites W2028401677 @default.
- W2106687572 cites W2042160477 @default.
- W2106687572 cites W2044837419 @default.
- W2106687572 cites W2045773814 @default.
- W2106687572 cites W2048020333 @default.
- W2106687572 cites W2057512208 @default.
- W2106687572 cites W2061142443 @default.
- W2106687572 cites W2064598952 @default.
- W2106687572 cites W2065175310 @default.
- W2106687572 cites W2068934649 @default.
- W2106687572 cites W2069018826 @default.
- W2106687572 cites W2070769983 @default.
- W2106687572 cites W2071152217 @default.
- W2106687572 cites W2072230362 @default.
- W2106687572 cites W2084611806 @default.
- W2106687572 cites W2087487832 @default.
- W2106687572 cites W2094597528 @default.
- W2106687572 cites W2097796010 @default.
- W2106687572 cites W2114918609 @default.
- W2106687572 cites W2119031668 @default.
- W2106687572 cites W2121208439 @default.
- W2106687572 cites W2127703608 @default.
- W2106687572 cites W2131464744 @default.
- W2106687572 cites W2133758259 @default.
- W2106687572 cites W2138521238 @default.
- W2106687572 cites W2153473625 @default.
- W2106687572 cites W2157603347 @default.
- W2106687572 cites W2162784999 @default.
- W2106687572 cites W2163239845 @default.
- W2106687572 cites W2164206876 @default.
- W2106687572 cites W2318667954 @default.
- W2106687572 doi "https://doi.org/10.1016/j.cbi.2009.09.024" @default.
- W2106687572 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19818742" @default.
- W2106687572 hasPublicationYear "2010" @default.
- W2106687572 type Work @default.
- W2106687572 sameAs 2106687572 @default.
- W2106687572 citedByCount "38" @default.
- W2106687572 countsByYear W21066875722012 @default.
- W2106687572 countsByYear W21066875722013 @default.
- W2106687572 countsByYear W21066875722014 @default.
- W2106687572 countsByYear W21066875722015 @default.
- W2106687572 countsByYear W21066875722016 @default.
- W2106687572 countsByYear W21066875722017 @default.
- W2106687572 countsByYear W21066875722018 @default.
- W2106687572 countsByYear W21066875722019 @default.
- W2106687572 countsByYear W21066875722020 @default.
- W2106687572 countsByYear W21066875722021 @default.
- W2106687572 countsByYear W21066875722022 @default.
- W2106687572 countsByYear W21066875722023 @default.
- W2106687572 crossrefType "journal-article" @default.
- W2106687572 hasAuthorship W2106687572A5006613124 @default.
- W2106687572 hasAuthorship W2106687572A5034471264 @default.
- W2106687572 hasAuthorship W2106687572A5042572280 @default.
- W2106687572 hasAuthorship W2106687572A5051198143 @default.
- W2106687572 hasAuthorship W2106687572A5069374998 @default.
- W2106687572 hasAuthorship W2106687572A5082703185 @default.
- W2106687572 hasAuthorship W2106687572A5084685500 @default.
- W2106687572 hasConcept C126322002 @default.
- W2106687572 hasConcept C185592680 @default.
- W2106687572 hasConcept C190283241 @default.
- W2106687572 hasConcept C202751555 @default.
- W2106687572 hasConcept C2776151105 @default.
- W2106687572 hasConcept C2777411675 @default.
- W2106687572 hasConcept C2777667348 @default.
- W2106687572 hasConcept C2778004101 @default.